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August 8, 2022

August 10, 2022

August 2, 2022
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Available Form:
Tablet
Manufacturer name:
Glaxosmithkline
Generic name:
naratriptan
Strength:
1mg, 2.5mg
Amerge (Naratriptan) belongs to a class of medications known as 5-hydroxytryptamine agonists. It is used to treat migraine attacks with or without aura (warning signs that occur prior to the onset of a migraine).
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Amerge (Naratriptan) belongs to a class of medications known as 5-hydroxytryptamine agonists. It is used to treat migraine attacks with or without aura (warning signs that occur prior to the onset of a migraine). It is not to be used for the prevention of migraine.
Migraine Headaches are thought to be caused by a widening of the blood vessels in the head. Amerge (Naratriptan) relieves migraine headaches by narrowing these vessels.
For most people, Amerge (Naratriptan) eliminates or reduces the symptoms of migraine including headache, nausea, vomiting, and sensitivity to light and sound.
Amerge (Naratriptan) may be available under multiple brand names and/or in several different forms. Any specific brand name of Amerge (Naratriptan) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Amerge (Naratriptan) may not be used for all of the conditions discussed here.
Your doctor may have suggested Amerge (Naratriptan) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Amerge (Naratriptan), speak to your doctor. Do not stop taking Amerge (Naratriptan) without consulting your doctor.
Do not give Amerge (Naratriptan) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Amerge (Naratriptan) if their doctor has not prescribed it.
The recommended adult single dose of Amerge (Naratriptan) ranges from 1 mg to 2.5 mg. The maximum recommended single dose is 2.5 mg.
Amerge (Naratriptan) should be taken as early as possible after the onset of a migraine headache, but is effective if taken at a later stage. A second tablet may be taken if the headache returns, but not sooner than 4 hours after the first tablet was taken. You should not take any more than 5 mg of Amerge (Naratriptan) in any 24-hour period (i.e., 2 of the 2.5 mg strength or 5 of the 1 mg strength).
If you do not get relief from the first dose of Amerge (Naratriptan), a second dose should not be taken for the same attack unless you talk with your doctor first, as it is unlikely to be of benefit.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
The tablets should be swallowed whole with fluids.
It is important to take Amerge (Naratriptan) exactly as prescribed. The safety of treating more than 4 migraines with Amerge (Naratriptan) in a 1-month period of time is not known. If you are experiencing more than 4 migraines in a month, contact your doctor.
Store Amerge (Naratriptan) at room temperature, protect it from light and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Amerge (Naratriptan). If you are concerned about side effects, discuss the risks and benefits of Amerge (Naratriptan) with your doctor.
The following side effects have been reported by at least 1% of people taking Amerge (Naratriptan). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
1 mg
Each white, film-coated, D-shaped tablet marked "GXCE3" on one side contains 1 mg of Amerge (Naratriptan). Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, titanium dioxide, and triacetin.
2.5 mg
Each green, film-coated, D-shaped tablet marked "GXCE5" on one side contains 2.5 mg of Amerge (Naratriptan). Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, indigo carmine aluminum lake (FD&C Blue No. 2), iron oxide yellow, lactose, magnesium stearate, microcrystalline cellulose, titanium dioxide, and triacetin.
Do not take Amerge (Naratriptan) if you:
There may be an interaction between Amerge (Naratriptan) and any of the following:
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If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Amerge (Naratriptan). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Amerge (Naratriptan).
Allergic reactions: If you are allergic to sulfonamides you may experience an allergic reaction to Amerge (Naratriptan). Reactions range from skin allergy to serious allergic reaction. Rarely, anaphylactic reactions to Amerge (Naratriptan) may occur. Because of the possibility of allergic reactions, people who are allergic to any of the other drugs of this class (5-hydroxytryptamine agonists) should not use Amerge (Naratriptan).
Blood pressure: Amerge (Naratriptan) may cause increases in blood pressure. If you have mild to moderately increased blood pressure, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
People with severe or uncontrolled high blood pressure should not take Amerge (Naratriptan).
Drowsiness/reduced alertness: Amerge (Naratriptan) may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how Amerge (Naratriptan) affects you.
Headache type: Amerge (Naratriptan) should only be used where there is a clear diagnosis of migraine headache.
Heart disease: There have been rare reports of heart attack and stroke occurring with people who have appeared to be otherwise healthy. If you have risk factors for heart disease, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
Risk factors for heart disease include high blood pressure, High Cholesterol levels, smoking, Obesity, Diabetes, a family history of heart disease, being male over 40 years old, or being a post-menopausal woman.
If you have heart disease you should not use Amerge (Naratriptan).
Kidney function: For people with reduced kidney function, it takes longer for Amerge (Naratriptan) to leave the body, which may result in an increase in side effects. If you have reduced kidney function or Kidney Disease, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
If you have severely reduced kidney function you should not use Amerge (Naratriptan).
Liver function: For people with reduced liver function, it takes longer for Amerge (Naratriptan) to leave the body, which may result in an increase in side effects. If you have reduced liver function or liver disease, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
If you have severely reduced liver function you should not use Amerge (Naratriptan).
Medication overuse headache: As with other medications for treating headaches, the overuse of Amerge (Naratriptan) may create a situation where the headache returns as the medication wears off, prompting the use of more medication. Do not take more Amerge (Naratriptan) than recommended by your doctor. If you require more than 5 mg of Amerge (Naratriptan) in a 24 hour period, or need to treat more than four headaches over 30 days, contact your doctor.
Medications containing ergotamine: After taking any ergotamine-containing preparation, wait at least 24 hours before taking Amerge (Naratriptan). Likewise, ergotamine-containing preparations should not be taken for at least 24 hours following Amerge (Naratriptan) administration.
Seizures: There have been rare reports of seizures occurring with Amerge (Naratriptan). If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
Serotonin syndrome: Severe reactions are possible when Amerge (Naratriptan) is combined with other medications that act on serotonin such as tricyclic antidepressants and serotonin reuptake inhibitors, medications used to treat Depression. These combinations must be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, changes in mental state including delirium and agitation. Coma and death are possible.
If you are taking antidepressants, discuss with your doctor how Amerge (Naratriptan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Amerge (Naratriptan), and whether any special monitoring is needed.
Pregnancy: Amerge (Naratriptan) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Amerge (Naratriptan), contact your doctor immediately.
Breast-feeding: It is not known if Amerge (Naratriptan) passes into breast milk. If you are a breast-feeding mother and are taking Amerge (Naratriptan), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Amerge (Naratriptan) have not been established for children, and its use by this age group is not recommended.
Seniors: There may be a higher risk of side effects such as high blood pressure and heart problems associated with the use of Amerge (Naratriptan) by people over the age of 65 years. The use of Amerge (Naratriptan) by people in this age group is not recommended.
References
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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