Ciprofloxacin is an antibiotic that belongs to the family of medications known as quinolones. It is used to treat infections caused by certain bacteria.
Available form
Injectable
Dosage
Manufacturer
Sandoz
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When ciprofloxacin is given by intravenous (into a vein) injection, the usual dose is 200 mg to 400 mg every 8 to 12 hours. The exact dose of ciprofloxacin depends on the condition being treated and other factors.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Ciprofloxacin Iv is always given in a setting with access to sterile equipment for preparation, usually in a hospital. If you are being treated at home, a health care professional will come to your home to set up each infusion.
It is important that Ciprofloxacin Iv be given exactly as recommended by your doctor. If you miss an appointment to receive ciprofloxacin, contact your doctor as soon as possible to reschedule your appointment.
Even if you start to feel better after the start of treatment, it's important to finish the entire amount that was prescribed. Store the intravenous solution at room temperature, protect it from light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who uses Ciprofloxacin Iv. If you are concerned about side effects, discuss the risks and benefits of Ciprofloxacin Iv with your doctor.
The following side effects have been reported by at least 1% of people using Ciprofloxacin Iv. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop using the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Ciprofloxacin Iv.
Ciprofloxacin injection USP by Sandoz is no longer being manufactured for sale in Canada. For brands that may still be available, search under ciprofloxacin. This article is being kept available for reference purposes only. If you are using Ciprofloxacin Iv, speak with your doctor or pharmacist for information about your treatment options.
Do not use ciprofloxacin if you:
There may be an interaction between ciprofloxacin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Ciprofloxacin Iv. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Ciprofloxacin Iv.
Health Canada has issued new restrictions concerning the use of ciprofloxacin. To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Allergic reactions: In rare cases, some people may develop an allergic reaction to Ciprofloxacin Iv. Signs of an allergic reaction include a severe rash, swollen face, or difficulty breathing. If these occur, get immediate medical attention.
Antibiotic-related diarrhea: Ciprofloxacin Iv, like other antibiotics, can cause a potentially dangerous, severe form of diarrhea called antibiotic-associated colitis or pseudomembranous colitis. Symptoms include severe, watery diarrhea that may be bloody. If you notice these symptoms, stop taking ciprofloxacin and contact your doctor as soon as possible.
Bacterial resistance: Misuse of an antibiotic such as ciprofloxacin may lead to the growth of resistant bacteria that will not be killed by the antibiotic. If this happens, the antibiotic may not work for you in the future. Although you may begin to feel better when you first start taking ciprofloxacin, take all the medication exactly as directed by your doctor to finish ridding your body of the infection and to prevent resistant bacteria from taking hold. Do not take ciprofloxacin or other antibiotics to treat a viral infection such as The Common Cold; antibiotics do not kill viruses, and using them to treat viral infections can lead to the growth of resistant bacteria.
Behaviour and nervous system: Rarely, ciprofloxacin may affect behaviour and the nervous system. These changes can include confusion, tremors, depression (including thoughts of harming yourself), hallucinations (hearing, seeing, or feeling things that are not actually there), agitation, anxiety, difficulty sleeping, or nightmares. Some people have experienced a "pins and needles" feeling or numbness that does not always go away when the medication is stopped. If you experience these or any other behaviour changes while taking Ciprofloxacin Iv, contact your doctor.
Blood glucose: Ciprofloxacin may cause changes in blood sugar levels (may cause a loss of blood glucose control) and glucose tolerance may change. It can cause either high or low blood glucose. People with Diabetes may find it necessary to monitor their blood sugar more frequently while using Ciprofloxacin Iv.
If you experience symptoms of low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heartbeat, weakness) or symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour), talk to your doctor.
Driving and operating heavy machinery: Ciprofloxacin may impair your ability to drive or operate machinery, especially when combined with alcohol. Do not drive or operate machinery until you know how this medication affects you.
Hypersensitivity syndrome: A Anaphylaxis (severe allergic reaction) called hypersensitivity syndrome has occurred for some people with the use of ciprofloxacin. This reaction involves a number of organs in the body and may be fatal if not treated quickly. Stop taking the medication and get immediate medical attention if you have symptoms of a severe allergic reaction, including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.
Kidney function: Kidney Disease or reduced kidney function may cause Ciprofloxacin Iv to build up in the body, causing side effects, since ciprofloxacin is removed from the body primarily by the kidneys. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ciprofloxacin Iv, and whether any special monitoring is needed.
Liver function: Ciprofloxacin may reduce liver function and can cause liver failure. If you have liver problems, discuss with your doctor how Ciprofloxacin Iv may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ciprofloxacin Iv, and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Neuromuscular disorders: Ciprofloxacin may cause increased muscle weakness for people with Myasthenia Gravis (an autoimmune disorder that causes muscle weakness). If you have myasthenia gravis, discuss with your doctor how Ciprofloxacin Iv may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ciprofloxacin Iv, and whether any special monitoring is needed.
Other infections: Use of ciprofloxacin for a long time may lead to yeast infections.
QT prolongation: Ciprofloxacin Iv can lengthen heartbeat as shown on an electrocardiogram test, also known as QT prolongation. Very rare cases of abnormal heartbeat have been reported by people taking ciprofloxacin, but these reports generally involved people who had conditions that predisposed them to abnormal heartbeat, or who had been taking other medications that can increase the risk of developing an abnormal heartbeat. If you have heart disease and abnormal heart rhythms, or are taking certain medications (e.g., Verapamil, atazanavir), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ciprofloxacin Iv, and whether any special monitoring is needed. If you develop heart palpitations (fast or irregular heartbeat) or experience fainting spells, stop taking ciprofloxacin and contact your doctor immediately.
Seizures: Rarely, seizures have been reported with this medication. If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Ciprofloxacin Iv may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ciprofloxacin Iv, and whether any special monitoring is needed. If you have a seizure while taking Ciprofloxacin Iv, stop taking it and get immediate medical attention.
Sucrose intolerance: The oral suspension form of Ciprofloxacin Iv contains sucrose. People who have a hereditary condition that makes them intolerant to some sugars should not take the oral suspension.
Sun sensitivity: People who take ciprofloxacin are more likely to experience Sunburn. Avoid exposure to excessive sunlight, including sunlamps and tanning beds. If you must spend time in the sun use sunblock with minimum SPF 30. Talk to your doctor if severe sun sensitivity occurs.
Tendinitis or tendon rupture: Ciprofloxacin may increase the chance of tendon injury, which occurs more commonly for seniors, people who are taking corticosteroid medications, and people who have had a kidney, heart, or lung transplant. This injury may cause permanent damage to the affected tendons. If there is any new pain in the tendons, stop taking ciprofloxacin, avoid physical exercise, and consult your doctor.
Pregnancy: Ciprofloxacin Iv should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Ciprofloxacin Iv, stop taking it immediately and call your doctor.
Breast-feeding: Ciprofloxacin Iv passes into breast milk. If you are a breast-feeding mother and are taking ciprofloxacin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children less than 18 years of age.
Seniors: People over the age of 65 may have a higher risk of side effects due to age-related decreases in kidney function.
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