Clonazepam belongs to the class of medications called benzodiazepines. In general, benzodiazepines are used as a sedative or to decrease seizures or anxiety.
Available form
Tablet
Dosage
Manufacturer
Meliapharm
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0.5 mg
Each round, orange, biplane tablet with bevelled edges, debossed "Clonazepam" on one side and "0.5" under a score line on the other side, contains clonazepam 0.5 mg. Nonmedicinal ingredients: corn starch, FD&C Yellow No. 6, lactose, magnesium stearate, and microcrystalline cellulose.
1 mg
Each round pink, biconvex tablet debossed with "Clonazepam" on one side and "1.0" on the other side, contains 1.0 mg of clonazepam. Nonmedicinal ingredients: corn starch, FD&C Red No. 40 lake, lactose, magnesium stearate, and microcrystalline cellulose.
2 mg
Each round, white, biplane tablet with bevelled edges, debossed with "Clonazepam" on one side and "2.0" underscore line on the other side, contains 2.0 mg of clonazepam. Nonmedicinal ingredients: corn starch, lactose, magnesium stearate, and microcrystalline cellulose.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Clonazepam R. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking Clonazepam R. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Clonazepam R.
Clonazepam is no longer being manufactured for sale in Canada. For brands that may still be available, search under "clonazepam". This article is being kept available for reference purposes only. If you are using Clonazepam R, speak with your doctor or pharmacist for information about your treatment options.
Do not use clonazepam if you:
Clonazepam may be used by people with open angle glaucoma who are receiving appropriate treatment.
There may be an interaction between clonazepam and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Clonazepam R. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, the Nicotine from cigarettes, or street drugs can affect the action of many medications; you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Clonazepam R.
HEALTH CANADA ADVISORY
October 30, 2020
Health Canada has issued new restrictions concerning the use of benzodiazepines and benzodiazepine-like prescription drugs. To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Alcohol: People taking Clonazepam R should not consume alcohol since doing so can reduce the effectiveness of Clonazepam R and increase the risk of side effects.
People who have an addiction to alcohol or other drugs should not take clonazepam except in rare situations under medical supervision.
Breathing: Clonazepam can suppress breathing. This effect on breathing may be more pronounced for people with breathing problems, brain damage, or who are taking other medications that suppress breathing (e.g., Codeine, Morphine). If you have severe breathing problems, discuss the risks and benefits of taking Clonazepam R your doctor.
Coordination problems: If you have a medical condition that affects coordination (e.g., spinal or cerebellar ataxia, discuss with your doctor how Clonazepam R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clonazepam R, and whether any special monitoring is needed.
Dependence and withdrawal: Physical dependence (a need to take regular doses to prevent physical symptoms) has been associated with benzodiazepines such as clonazepam. Severe withdrawal symptoms may occur if the dose is significantly reduced or suddenly stopped. These symptoms include seizures, irritability, nervousness, sleep problems, agitation, tremors, Diarrhea, abdominal cramps, vomiting, memory impairment, headache, muscle pain, extreme anxiety, tension, restlessness, and confusion. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms. Do not suddenly stop taking Clonazepam R without talking to your doctor.
Depression: Clonazepam, like other benzodiazepines, has been known to cause mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clonazepam R, and whether any special monitoring is needed. If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Clonazepam R contact your doctor as soon as possible.
Clonazepam is not recommended for use by people with depression or psychosis or who have attempted suicide.
Drowsiness/reduced alertness: Because clonazepam causes drowsiness and sedation, avoid activities requiring mental alertness, judgment, and physical coordination (such as driving or operating machinery) while taking it. This is particularly true when first taking the medication and until you have established how clonazepam affects you. Alcohol can increase the drowsiness effects and should be avoided.
Grapefruit juice: Avoid drinking grapefruit juice while you are taking Clonazepam R as it can increase the levels of clonazepam in your blood.
Kidney function: Decreased kidney function or Kidney Disease may cause Clonazepam R to build up in the body, causing side effects. If you have kidney disease or reduced kidney function, discuss with your doctor how Clonazepam R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clonazepam R, and whether any special monitoring is needed.
Lactose intolerance: Lactose is one of the ingredients in this medication. If you have a hereditary condition that makes you intolerant to lactose, discuss other alternatives with your doctor.
Liver function: If you have liver disease or decreased liver function, discuss with your doctor how Clonazepam R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clonazepam R, and whether any special monitoring is needed. People with severe liver problems should not take Clonazepam R.
Memory: Clonazepam R may impair recent memory. If you experience this while taking Clonazepam R, contact your doctor.
Porphyria: If you have porphyria, discuss with your doctor how Clonazepam R may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Clonazepam R, and whether any special monitoring is needed.
Seizures: For some people taking Clonazepam R, seizures may worsen or a new type of seizure can occur. If you experience worsening seizures or the frequency of your seizures does not decrease while taking this medication, contact your doctor.
Pregnancy: Taking clonazepam during pregnancy can increase the risk of certain birth defects. Clonazepam R should only be used during pregnancy if the benefits outweigh the risks. If you become pregnant while taking Clonazepam R, contact your doctor immediately. Do not stop taking Clonazepam R suddenly, as this may result in withdrawal symptoms. Discuss the options with your doctor and follow their instructions closely.
Breast-feeding: Clonazepam R passes into breast milk. If you are a breast-feeding mother and are taking clonazepam, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: If long-term use of clonazepam is being considered for a child, discuss with your child's doctor the benefits and the risks of clonazepam use. Long-term use may have an effect on your child’s physical and mental development.
Seniors: Seniors may be at increased risk for the sedative and impaired coordination effects of Clonazepam R. This can increase the risk of falls and fractures. Seniors may require lower doses of Clonazepam R.
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