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Diazemuls (Diazepam) belongs to the class of medications called benzodiazepines. It is used for the short-term relief of symptoms of mild-to-moderate anxiety or alcohol withdrawal (such as agitation).
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Diazemuls (Diazepam) belongs to the class of medications called benzodiazepines. It is used for the short-term relief of symptoms of mild-to-moderate anxiety or alcohol withdrawal (such as agitation). It is also used for reducing muscle spasms. It works by slowing down the nerves in the brain (i.e., central nervous system).
The injectable form of Diazemuls (Diazepam) is used to control prolonged seizures.
Diazemuls (Diazepam) may be available under multiple brand names and/or in several different forms. Any specific brand name of Diazemuls (Diazepam) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Diazemuls (Diazepam) may not be used for all of the conditions discussed here.
Your doctor may have suggested Diazemuls (Diazepam) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given Diazemuls (Diazepam), speak to your doctor. Do not stop using Diazemuls (Diazepam) without consulting your doctor.
Do not give Diazemuls (Diazepam) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Diazemuls (Diazepam) if their doctor has not prescribed it.
The recommended dose of Diazemuls (Diazepam) for adults ranges from 2 mg to 10 mg, taken 2 to 4 times daily. For children older than 6 months, the initial dose usually ranges from 1 mg to 2.5 mg, taken 3 or 4 times daily.
It is important that the dose be individualized to your specific needs to avoid excessive sleepiness or motor impairment.
Diazemuls (Diazepam) is normally used for a short period of time or as required. It may be habit-forming when taken for long periods of time. If you have been using Diazemuls (Diazepam) regularly for a long period of time (i.e., more than 1 month), do not stop using the medication without speaking with your doctor. To avoid withdrawal effects, a gradual reduction in dose is usually recommended when stopping Diazemuls (Diazepam).
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use Diazemuls (Diazepam) exactly as prescribed by your doctor. If you miss a dose, administer it as soon as you remember and continue with your regular schedule. If your next dose is in less than 6 hours, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store at room temperature in a dry place. Keep out of reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Diazemuls (Diazepam). If you are concerned about side effects, discuss the risks and benefits of Diazemuls (Diazepam) with your doctor.
The following side effects have been reported by at least 1% of people taking Diazemuls (Diazepam). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Diazemuls (Diazepam).
Diazemuls injection is no longer being manufactured for sale in Canada. For brands that may still be available, search under Diazemuls (Diazepam). This article is being kept available for reference purposes only. If you are using Diazemuls (Diazepam), speak with your doctor or pharmacist for information about your treatment options.
Do not take Diazemuls (Diazepam) if you:
Do not give Diazemuls (Diazepam) to infants under 6 months of age.
There may be an interaction between Diazemuls (Diazepam) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Diazemuls (Diazepam). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Diazemuls (Diazepam).
HEALTH CANADA ADVISORY
October 30, 2020
Health Canada has issued new restrictions concerning the use of benzodiazepines and benzodiazepine-like prescription drugs. To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Alcohol and other medications that cause drowsiness: Alcohol and other medications that cause drowsiness, such as antidepressants, sleeping pills, anxiety medications, or narcotic pain relievers, should be avoided when you are taking Diazemuls (Diazepam). Combining any of these medications with Diazemuls (Diazepam) can result in severe drowsiness, breathing problems, and possibly coma and death. People who have an addiction to alcohol or other medications should not take Diazemuls (Diazepam), except in rare situations under medical supervision.
Dependence and withdrawal: Physical dependence (a need to take regular doses to prevent physical symptoms) has been associated with benzodiazepines such as Diazemuls (Diazepam). Severe withdrawal symptoms may occur if the dose is significantly reduced or suddenly discontinued. These symptoms include seizures, irritability, nervousness, sleep problems, agitation, tremors, Diarrhea, abdominal cramps, vomiting, memory impairment, headache, muscle pain, extreme anxiety, tension, restlessness, and confusion. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms.
Rebound anxiety may also occur if treatment with Diazemuls (Diazepam) is stopped abruptly. Rebound anxiety is a temporary syndrome where the symptoms that led to use of Diazemuls (Diazepam) come back stronger than before.
Depression: Benzodiazepine medications such as Diazemuls (Diazepam) have been known to cause mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Diazemuls (Diazepam) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Diazemuls (Diazepam), and whether any special monitoring is needed. If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Diazemuls (Diazepam), contact your doctor as soon as possible.
Drowsiness/reduced alertness: Because Diazemuls (Diazepam) causes drowsiness and sedation, do not engage in activities requiring mental alertness, judgment, and physical coordination (such as driving or operating machinery) while taking it. This is particularly true when you first start taking the medication and until you find out how the Diazemuls (Diazepam) affects you. Alcohol can increase the drowsiness effects and should be avoided.
Liver function: Liver disease or reduced liver function may cause Diazemuls (Diazepam) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Diazemuls (Diazepam) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Diazemuls (Diazepam), and whether any special monitoring is needed.
Suicidal or agitated behaviour: People taking Diazemuls (Diazepam) sometimes feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. This behaviour is more likely to occur in children or seniors, however it can occur in other adults, particularly those with mental or emotional disorders. These symptoms may occur within several weeks after starting Diazemuls (Diazepam). If you experience these side effects or notice them in a family member who is taking Diazemuls (Diazepam), contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking Diazemuls (Diazepam).
Pregnancy: Diazemuls (Diazepam) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Diazemuls (Diazepam), contact your doctor immediately. Babies born to mothers who have used Diazemuls (Diazepam) regularly during late pregnancy may have breathing difficulties and show signs of withdrawal when they are first born.
Breast-feeding: Diazemuls (Diazepam) passes into breast milk. If you are a breast-feeding mother and are taking Diazemuls (Diazepam), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of Diazemuls (Diazepam) have not been determined for use by children less than 6 months old.
Seniors: Seniors may be at increased risk for the sedative and impaired coordination effects of Diazemuls (Diazepam). Seniors should be started on lower doses of Diazemuls (Diazepam). They also need to use extra caution, for example, when getting up during the night.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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