Ibrance

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Available Form:  

CAPSULE

Manufacturer name:  

Pfizer

Generic name:  

PALBOCICLIB

Strength:  

75MG

What is Ibrance?

Ibrance (Palbociclib) belongs to a group of cancer-fighting medications called protein kinase inhibitors.  It works by recognizing certain types of cancer cells and blocking the action of chemicals that cause them to divide and grow.

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Ibrance Indication

Ibrance (Palbociclib) belongs to a group of cancer-fighting medications called protein kinase inhibitors. It works by recognizing certain types of cancer cells and blocking the action of chemicals that cause them to divide and grow. This may slow down or stop cancers from growing and dividing.

Ibrance (Palbociclib) is used in combination with other medication, to treat advanced Breast Cancer that has spread to other parts of the body (metastasized).

Ibrance (Palbociclib) may be available under multiple brand names and/or in several different forms. Any specific brand name of Ibrance (Palbociclib) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Ibrance (Palbociclib) may not be used for all of the conditions discussed here.

Your doctor may have suggested Ibrance (Palbociclib) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Ibrance (Palbociclib), speak to your doctor. Do not stop taking Ibrance (Palbociclib) without consulting your doctor.

Do not give Ibrance (Palbociclib) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Ibrance (Palbociclib) if their doctor has not prescribed it.

Ibrance Dosage

The recommended dose of Ibrance (Palbociclib) is 125 mg taken by mouth, once a day for 21 days, followed by 7 days without taking the medication. This forms a 28-day cycle, which is repeated as long as you are benefiting from the medication. Depending on the side effects you experience and how well you tolerate Ibrance (Palbociclib), your doctor may reduce the dose.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

There are two forms of Ibrance (Palbociclib): capsules and tablets. Ibrance (Palbociclib) capsules should be taken with food. Ibrance (Palbociclib) tablets may be taken with or without food. Try to take Ibrance (Palbociclib) the same way and at the same time each day, to make sure a constant amount of medication stays in your body.

Swallow Ibrance (Palbociclib) whole with some fluid. Do not crush, chew, or open the capsules or tablets before swallowing them. If you find a broken, cracked, or open capsule or tablet, discard it safely. Do not take any capsule or tablet that is not intact.

It is important to take Ibrance (Palbociclib) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. If you vomit after taking your dose for the day, do not take another dose. Continue taking the medication the next day. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Ibrance (Palbociclib) at room temperature, in its original container, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Ibrance Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Ibrance (Palbociclib). If you are concerned about side effects, discuss the risks and benefits of Ibrance (Palbociclib) with your doctor.

The following side effects have been reported by at least 1% of people taking Ibrance (Palbociclib). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Constipation
  • cough
  • Diarrhea
  • hair thinning or loss
  • headache
  • loss of appetite
  • mouth sores
  • nausea
  • rash
  • tiredness
  • vomiting
  • weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:

  • Fever
  • tingling in the arms or legs
  • shortness of breath
  • signs of Anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
  • signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
  • signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • symptoms of lung inflammation (e.g., cough, shortness of breath, trouble breathing)
  • tingling or abnormal feeling (especially in the arms and legs)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • symptoms of an allergic reaction (e.g., difficulty breathing, Hives, itchy skin rash, or swelling of the mouth or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Ibrance (Palbociclib).

Ibrance Available form

Capsules

75 mg
Each opaque, hard gelatin, size 2 capsule with light orange cap and body, printed with white ink "Pfizer" on the cap, "PBC 75" on the body, contains 75 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, colloidal silicon dioxide, and magnesium stearate; capsule shell: gelatin, red iron oxide, yellow iron oxide, and titanium dioxide; printing ink: shellac, titanium dioxide, ammonium hydroxide, propylene glycol, and simethicone.

100 mg
Each opaque, hard gelatin, size 1 capsule with caramel cap and light orange body, printed with white ink "Pfizer" on the cap, "PBC 100" on the body, contains 100 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, colloidal silicon dioxide, and magnesium stearate; capsule shell: gelatin, red iron oxide, yellow iron oxide, and titanium dioxide; printing ink: shellac, titanium dioxide, ammonium hydroxide, propylene glycol, and simethicone.

125 mg
Each opaque, hard gelatin, size 0 capsule with caramel cap and body, printed with white ink "Pfizer" on the cap, "PBC 125" on the body, contains 125 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, and hard gelatin capsule shells; capsule shell: gelatin, red iron oxide, yellow iron oxide, and titanium dioxide; printing ink: shellac, titanium dioxide, ammonium hydroxide, propylene glycol, and simethicone.

Tablets

75 mg
Each round, light purple, film-coated tablet, debossed with "Pfizer" on one side and "PBC 75" on the other side, contains 75 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, red iron oxide succinic acid, titanium dioxide, and triacetin.

100 mg
Each oval, green, film-coated tablet, debossed with "Pfizer" on one side and "PBC 100" on the other side, contains 100 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, succinic acid, titanium dioxide, triacetin, and yellow iron oxide.

125 mg
Each oval, light purple, film-coated tablet, debossed with "Pfizer" on one side and "PBC 125" on the other side, contains 125 mg of Ibrance (Palbociclib). Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, red iron oxide, succinic acid, titanium dioxide, and triacetin.

Who should not take Ibrance (Palbociclib)?

Do not take Ibrance (Palbociclib) if you are allergic to Ibrance (Palbociclib) or any ingredients of the medication.

Ibrance Contraindications

Do not take Ibrance (Palbociclib) if you are allergic to Ibrance (Palbociclib) or any ingredients of the medication.

Ibrance Precautions

There may be an interaction between Ibrance (Palbociclib) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Ibrance (Palbociclib). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Ibrance Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Ibrance (Palbociclib).

Anemia: Ibrance (Palbociclib) may cause low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired or pale skin, contact your doctor as soon as possible.

Your doctor will do blood tests regularly to monitor the number of specific types of blood cells, including red blood cells, in your blood.

Drowsiness/dizziness: Ibrance (Palbociclib) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how Ibrance (Palbociclib) affects you.

Fruit/fruit juice: Certain fruits or their juices may change the amount of Ibrance (Palbociclib) in your body. Do not consume grapefruit, grapefruit juice, starfruit, pomegranate, or Seville oranges while taking Ibrance (Palbociclib).

Infection: As well as killing cancer cells, Ibrance (Palbociclib) can reduce the number of cells that fight infection in the body (white blood cells). If possible, avoid contact with people with contagious infections. Tell your doctor immediately if you notice signs of an infection, such as fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness. Your doctor will do blood tests regularly to monitor the number of specific types of blood cells in your blood.

Liver function: If you have liver problems, discuss with your doctor how Ibrance (Palbociclib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ibrance (Palbociclib), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Ibrance (Palbociclib).

Lung inflammation: Rarely, some people taking Ibrance (Palbociclib) have experienced lung inflammation (interstitial lung disease), causing difficulty breathing. This problem can be severe and life-threatening. If you experience new or worsening shortness of breath or cough (with or without fever) at any time while you are taking Ibrance (Palbociclib), contact your doctor immediately.

Male fertility: Ibrance (Palbociclib) may impair male fertility. Men should consider sperm preservation prior to starting treatment with Ibrance (Palbociclib). Men whose partners could become pregnant should use effective birth control during treatment and for at least 97 days after the last dose of Ibrance (Palbociclib).

Pregnancy: Ibrance (Palbociclib) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Ibrance (Palbociclib), contact your doctor immediately. If you are able to become pregnant, you should use effective birth control while you are taking Ibrance (Palbociclib) and for at least 21 days after stopping the medication. Men taking Ibrance (Palbociclib) whose partners could become pregnant should use effective birth control during treatment and for at least 97 days after the last dose of Ibrance (Palbociclib).

Breast-feeding: It is not known if Ibrance (Palbociclib) passes into breast milk. If you are breast-feeding and are taking Ibrance (Palbociclib), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Ibrance (Palbociclib) have not been established for children.

Ibrance frequently asked questions

How To Buy Ibrance Online?

You can buy Ibrance online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Ibrance?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Ibrance in Canada?

Shipping cost for Ibrance to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Ibrance delivered to my home?

You could get Ibrance delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Ibrance in Canada for free?

You can get Ibrance for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Ibrance for free.

Can I consult a doctor online to get Ibrance?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Ibrance.

Can I buy Ibrance without a prescription?

You need a valid prescription to buy Ibrance from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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