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Rabeprazole belongs to the class of medications known as proton pump inhibitors (PPIs). It works by slowing or preventing the production of acid in the stomach.
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Rabeprazole belongs to the class of medications known as proton pump inhibitors (PPIs). It works by slowing or preventing the production of acid in the stomach. Rabeprazole is used to treat and maintain healing of GERD (Gastroesophageal reflux disease) (GERD). It is also used to treat symptoms, such as heartburn and regurgitation, of non-erosive reflux disease (NERD).
It is also used for short-term treatment in the healing and relief of symptoms associated with duodenal and gastric ulcers. Rabeprazole is used in combination with antibiotics to treat ulcers caused by the bacterium Helicobacter pylori. Finally, rabeprazole is used for long-term treatment of conditions associated with constant production of excess acid in the stomach, including Zollinger-Ellison syndrome.
Dom Rabeprazole may be available under multiple brand names and/or in several different forms. Any specific brand name of Dom Rabeprazole may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Dom Rabeprazole may not be used for all of the conditions discussed here.
Your doctor may have suggested Dom Rabeprazole for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Dom Rabeprazole, speak to your doctor. Do not stop taking Dom Rabeprazole without consulting your doctor.
Do not give Dom Rabeprazole to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Dom Rabeprazole if their doctor has not prescribed it.
The dose of rabeprazole used depends on the condition being treated.
To treat non-erosive reflux disease (NERD), the recommended adult dose of rabeprazole is 10 mg to 20 mg, taken once daily for up to 4 weeks.
To treat gastroesophageal reflux disease (GERD) with esophagitis, the recommended adult dose of rabeprazole is 20 mg, taken once daily. The recommended adult dose for maintaining long-term healing of GERD is 10 mg to 20 mg, taken once daily. The usual length of treatment for GERD is 4 to 8 weeks.
To treat duodenal ulcer, the recommended adult dose of rabeprazole is 20 mg, taken once daily for a period of up to 4 weeks.
To treat gastric or stomach ulcer, the recommended adult dose of rabeprazole is 20 mg, taken once daily for a period of up to 6 weeks.
To treat ulcer caused by Helicobacter pylori infection, the recommended adult dose is 20 mg, taken twice daily for 7 days in combination with 2 antibiotics, usually amoxicillin and clarithromycin. If you are taking rabeprazole in combination with antibiotic drugs, it is important that you take all medications at the correct time of day and for the entire treatment period as recommended by your doctor.
To treat Zollinger-Ellison syndrome, the recommended adult starting dose of rabeprazole is 60 mg, taken once daily. Some people may require higher doses. Your doctor will adjust the dose of Dom Rabeprazole as needed.
Rabeprazole delayed release tablet has been designed to work throughout the day, and therefore needs to be taken only once daily. Dom Rabeprazole may be taken with or without food. Swallow the tablets whole with a beverage. Do not chew, crush, or split the tablets.
Most people will experience some improvements in symptoms 1 to 2 weeks after starting rabeprazole. It may take up to 4 weeks for people to experience maximum benefit from Dom Rabeprazole.
Keep taking Dom Rabeprazole and finish all the tablets as recommended by your doctor even if you start to feel better. If the symptoms that were causing you problems have not gone away by the time you finish your medication or as discussed with your doctor, call your doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Dom Rabeprazole exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Dom Rabeprazole at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Dom Rabeprazole. If you are concerned about side effects, discuss the risks and benefits of Dom Rabeprazole with your doctor.
The following side effects have been reported by at least 1% of people taking Dom Rabeprazole. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Dom Rabeprazole.
Each pink, round, biconvex coated tablet ink-printed in black with "RB10" on one side and nothing on the other side contains 10 mg of rabeprazole sodium. Nonmedicinal ingredients: ammonium hydroxide, hydroxypropyl cellulose, hydroxypropyl methylcellulose, manitol, magnesium oxide, magnesium stearate, methacrylic acid copolymer, polyethylene glycol, shellac glaze, sodium lauryl sulfate, talc, titanium dioxide, triethyl citrate, zein and antifoam, hypromellose, iron oxide black, iron oxide red and lecithin (soya).
Each yellow, round, biconvex coated tablet, ink-printed in red with "RB20" on one side and nothing on the other side contains 20 mg of rabeprazole sodium. Nonmedicinal ingredients: ammonium hydroxide, hydroxypropyl cellulose, hydroxypropyl methylcellulose, manitol, magnesium oxide, magnesium stearate, methacrylic acid copolymer, polyethylene glycol, shellac glaze, sodium lauryl sulfate, talc, titanium dioxide, triethyl citrate, zein, FD&c Red no. 40 aluminum lake, propylene glycol and yellow iron oxide
Do not take Dom Rabeprazole if you:
There may be an interaction between rabeprazole and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Dom Rabeprazole. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Dom Rabeprazole.
Diarrhea: When gastric acid is decreased, the number of bacteria normally in the digestive system increases. Occasionally, this can cause serious infection in the digestive tract. If you experience watery, foul-smelling bowel movements after starting to take rabeprazole, contact your doctor as soon as possible.
Liver function: Liver disease or reduced liver function may cause Dom Rabeprazole to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Dom Rabeprazole may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Rabeprazole, and whether any special monitoring is needed.
Magnesium levels: Rabeprazole may rarely cause low magnesium levels in people who take Dom Rabeprazole for a prolonged period of time. Low magnesium may occur after at least 3 months, but usually after a year of treatment. If you have low magnesium levels in your blood, you should discuss with your doctor about how Dom Rabeprazole may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Rabeprazole, and whether any special monitoring is needed.
Methotrexate interaction: Rabeprazole, like other medications in this group, may interact with methotrexate when the two medications are used at the same time. This combination may lead to higher than expected amounts of methotrexate in the body and can cause serious side effects, including kidney damage, irregular heartbeat, Anemia, or infection. If you take rabeprazole, and are also going to receive a dose of methotrexate, discuss with your doctor how Dom Rabeprazole may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Rabeprazole, and whether any special monitoring is needed.
More serious conditions of the stomach and intestines: If you experience symptoms of a more serious condition of the stomach and intestines (e.g., trouble swallowing, unplanned weight loss, persistent vomiting, vomiting blood, or black stools) while taking Dom Rabeprazole, contact your doctor immediately.
Osteoporosis fractures: Long term use of rabeprazole may be related to an increased risk of bone fractures in the hip, wrist or spine, as a result of weakened bones. This risk is further increased if you are at risk of developing osteoporosis. If you have osteoporosis or have risk factors for developing osteoporosis, discuss with your doctor how Dom Rabeprazole may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dom Rabeprazole, and whether any special monitoring is needed.
Vitamin B12: Long-term use of rabeprazole may lead to vitamin B12 deficiency. If you are a vegetarian or have low vitamin B12 levels, discuss with your doctor whether any special monitoring is required.
Pregnancy: Dom Rabeprazole should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Dom Rabeprazole, contact your doctor immediately.
Breast-feeding: It is not known if rabeprazole passes into breast milk. If you are a breast-feeding mother and are taking Dom Rabeprazole, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children and adolescents: The safety and effectiveness of using Dom Rabeprazole have not been established for children and adolescents less than 18 years of age.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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