Pariet

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Pariet (Rabeprazole). If you are concerned about side effects, discuss the risks and benefits of Pariet (Rabeprazole) with your doctor.

The following side effects have been reported by at least 1% of people taking Pariet (Rabeprazole). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Diarrhea (mild)
• dizziness
• headache
• itchiness
• rash

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abnormal or fast heart beat
• blood in stool
• a fracture (broken bone)
• jerking movements or shaking
• jitteriness
• muscle weakness
• rash on cheeks or arms that gets worse in sun
• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
• sore muscles
• spasms of the hands and feet
• spasm of the voice box

Stop taking the medication and seek immediate medical attention if any of the following occur:

• convulsions (seizures)
• signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
• signs of a severe skin reaction (e.g., blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with Fever or discomfort)
• signs of a serious bacterial bowel inflammation or infection (e.g., severe [watery or bloody] diarrhea, fever, abdominal pain or tenderness)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pariet (Rabeprazole).

10 mg
Each pink enteric-coated tablet, printed "ε 241" on one side, contains 10 mg of Pariet (Rabeprazole) sodium. Nonmedicinal ingredients: mannitol, hydroxypropyl cellulose, magnesium oxide, low substituted hydroxypropyl cellulose, magnesium stearate, ethylcellulose, hydroxypropyl methylcellulose phthalate, diacetylated monoglycerides, talc, titanium dioxide, iron oxide (black, red, or yellow), and carnauba wax.

20 mg
Each light yellow enteric-coated tablet, printed "ε 243" on one side, contains 20 mg of Pariet (Rabeprazole) sodium. Nonmedicinal ingredients: mannitol, hydroxypropyl cellulose, magnesium oxide, low substituted hydroxypropyl cellulose, magnesium stearate, ethylcellulose, hydroxypropyl methylcellulose phthalate, diacetylated monoglycerides, talc, titanium dioxide, iron oxide (black, red, or yellow), carnauba wax, and glycerine fatty acid ester.

Do not take Pariet (Rabeprazole) if you:

• are allergic to Pariet (Rabeprazole) or any ingredients of the medication
• are allergic to other proton pump inhibitors
• are taking the medication rilpivirine

There may be an interaction between Pariet (Rabeprazole) and any of the following:

• amphetamines (e.g., Dextroamphetamine)
• Apalutamide
• "azole" antifungal medications (e.g., itraconazole, fluconazole, ketoconazole, posaconazole)
• bisphosphonates (e.g., Alendronate, Risedronate)
• Bosentan
• Capecitabine
• Carbamazepine
• cefuroxime
• certain protein kinase inhibitors (e.g., Bosutinib, Dabrafenib, Dasatinib, Erlotinib Nilotinib
• Clopidogrel
• Deferasirox
• delavirdine
• Dexamethasone
• dexmethylphenidate
• Digoxin
• doxycycline
• Enzalutamide
• HIV protease inhibitors (e.g., atazanavir, indinavir, nelfinavir, ritonavir, saquinavir)
• iron salts
• ledipasvir
• Mesalamine
• methotrexate
• Methylphenidate
• Mitotane
• Modafinil
• mycophenolate
• Phenobarbital
• Phenytoin
• primidone
• raltegravir
• rifabutin
• rifampin
• rilpivirine
• Riociguat
• St. John's wort
• siltuximab
• "statin" cholesterol medications (e.g., Atorvastatin, Lovastatin, Simvastatin)
• Tacrolimus
• Tocilizumab
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Pariet (Rabeprazole). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Pariet (Rabeprazole).

Diarrhea: When gastric acid is decreased, the number of bacteria normally in the digestive system increases. Occasionally, this can cause serious infection in the digestive tract. If you experience watery, foul-smelling bowel movements after starting to take Pariet (Rabeprazole), contact your doctor as soon as possible.

Liver function: Liver disease or reduced liver function may cause Pariet (Rabeprazole) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Magnesium levels: Pariet (Rabeprazole) may rarely cause low magnesium levels in people who take Pariet (Rabeprazole) for a prolonged period of time. Low magnesium may occur after at least 3 months, but usually after a year of treatment. If you have low magnesium levels in your blood, you should discuss with your doctor about how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Methotrexate interaction: Pariet (Rabeprazole), like other medications in this group, may interact with methotrexate when the two medications are used at the same time. This combination may lead to higher than expected amounts of methotrexate in the body and can cause serious side effects, including kidney damage, irregular heartbeat, Anemia, or infection. If you take Pariet (Rabeprazole), and are also going to receive a dose of methotrexate, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

More serious conditions of the stomach and intestines: If you experience symptoms of a more serious condition of the stomach and intestines (e.g., trouble swallowing, unplanned weight loss, persistent vomiting, vomiting blood, or black stools) while taking Pariet (Rabeprazole), contact your doctor immediately.

Osteoporosis fractures: Long term use of Pariet (Rabeprazole) may be related to an increased risk of bone fractures in the hip, wrist or spine, as a result of weakened bones. This risk is further increased if you are at risk of developing osteoporosis. If you have osteoporosis or have risk factors for developing osteoporosis, discuss with your doctor how Pariet (Rabeprazole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pariet (Rabeprazole), and whether any special monitoring is needed.

Vitamin B12: Long-term use of Pariet (Rabeprazole) may lead to vitamin B12 deficiency. If you are a vegetarian or have low vitamin B12 levels, discuss with your doctor whether any special monitoring is required.

Pregnancy: Pariet (Rabeprazole) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Pariet (Rabeprazole), contact your doctor immediately.

Breast-feeding: It is not known if Pariet (Rabeprazole) passes into breast milk. If you are a breast-feeding mother and are taking Pariet (Rabeprazole), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using Pariet (Rabeprazole) have not been established for children and adolescents less than 18 years of age.