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Memantine belongs to the group of medications known as NMDA receptor antagonists. It is used alone or with other medications to treat people with moderate-to-severe Alzheimer's Disease.
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Memantine belongs to the group of medications known as NMDA receptor antagonists. It is used alone or with other medications to treat people with moderate-to-severe Alzheimer's Disease. Memantine does not cure Alzheimer's disease, but it is used to decrease the symptoms. It works in the brain to block the effect of some chemicals that cause symptoms of Alzheimer's disease such as decreased memory and other mental functions.
Act Memantine may be available under multiple brand names and/or in several different forms. Any specific brand name of Act Memantine may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Act Memantine may not be used for all of the conditions discussed here.
Your doctor may have suggested Act Memantine for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Act Memantine, speak to your doctor. Do not stop taking Act Memantine without consulting your doctor.
Do not give Act Memantine to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Act Memantine if their doctor has not prescribed it.
The usual starting dose of memantine is 5 mg once daily. This dose is gradually increased, usually over a one-month period, to 10 mg twice daily. By gradually increasing the dose, the side effects of this medication are less severe.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Memantine tablets can be taken with or without food. The tablets should be swallowed whole with a glass of water and should not be chewed.
It is important to take Act Memantine exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Act Memantine at room temperature in a dry place and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of Act Memantine with your doctor.
The following side effects have been reported by at least 1% of people taking Act Memantine. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Act Memantine.
Each white-to-off-white, film-coated, capsule-shaped, biconvex tablet, with "MT 5" on one side and an arrow logo on the other side contains memantine 5 mg. Nonmedicinal ingredients: lactose monohydrate, microcrystalline cellulose and magnesium stearate; filmcoating: titanium dioxide, lactose monohydrate, polyethylene glycol, and hydroxypropyl methylcellulose.
Each white-to-off-white, film-coated, peanut-shaped, biconvex tablet with "MT | 10" on one side and a logo on the other side contains memantine 10 mg. Nonmedicinal ingredients: lactose monohydrate, microcrystalline cellulose and magnesium stearate; film coating: titanium dioxide, lactose monohydrate, polyethylene glycol, and hydroxypropyl methylcellulose.
Do not take Act Memantine if you are allergic to memantine or any ingredients of the medication.
There may be an interaction between memantine and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Act Memantine.
Eyes: Memantine may build up in the tear fluid and contribute to changes in the eyes and possible changes in vision. People taking memantine should have regular check-ups from their eye doctor. If you notice any changes to your vision, contact your doctor as soon as possible.
Heart disease: Memantine may cause increased blood pressure, slowed heartbeat and occasionally, heart failure. If you have heart problems, discuss with your doctor how Act Memantine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Act Memantine, and whether any special monitoring is needed.
Kidney function: The kidneys remove mematadine from the body. When the kidneys aren't working properly, the medication can build up in the body and cause side effects. Memantine is not recommended for people with severe Kidney Disease.
If you have reduced kidney function or moderate kidney disease you may need a lower dose of memantine. Discuss with your doctor how Act Memantine may affect your medical condition and whether any special monitoring is needed.
Liver function: The safety of memantine when given to someone with severely reduced liver function has not been studied and is not recommended. If you have reduced liver function or liver disease, discuss with your doctor how Act Memantine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Act Memantine, and whether any special monitoring is needed.
Reduced elimination from the body: The elimination of memantine from the body can be reduced in certain situations. These include changing from a normal diet to a strict vegetarian diet, taking certain medications (e.g., sodium bicarbonate, Acetazolamide), having a kidney condition called renal tubular acidosis, or having a urinary tract infection. Your doctor will monitor your condition closely in these situations.
Seizures: Memantine has not been studied for use by people who have seizure disorders (such as Epilepsy). If you have a history of seizure disorder, discuss with your doctor how Act Memantine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Act Memantine, and whether any special monitoring is needed.
Pregnancy: Act Memantine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if memantine passes into breast milk. If you are a breast-feeding mother and are taking Act Memantine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Act Memantine have not been established for children.
Seniors: There is limited information about the safety of memantine for people over the age of 85.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
August 8, 2022
August 10, 2022
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