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Available Form:   Tablet
Manufacturer name:   Lundbeck
Generic name:   vortioxetine
Strength:   5mg, 10mg, 20mg

What is Trintellix?

Trintellix (Vortioxetine) belongs to the family of medications known as antidepressants. More specifically, it is a serotonin modulator.

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Trintellix frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Trintellix in Canada?

Shipping cost for Trintellix to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Trintellix delivered to my home?

You could get Trintellix delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Trintellix in Canada for free?

You can get Trintellix for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Trintellix for free.

Trintellix How to Take

Trintellix (Vortioxetine) belongs to the family of medications known as antidepressants. More specifically, it is a serotonin modulator. It works by increasing the effectiveness of how serotonin is used in the brain. Serotonin is a chemical produced by the body that is associated with mood and emotion.

Trintellix (Vortioxetine) is used to treat the symptoms of major depressive disorder in adults and to keep the symptoms of Depression from returning.

Trintellix (Vortioxetine) may be available under multiple brand names and/or in several different forms. Any specific brand name of Trintellix (Vortioxetine) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Trintellix (Vortioxetine) may not be used for all of the conditions discussed here.

Your doctor may have suggested Trintellix (Vortioxetine) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Trintellix (Vortioxetine), speak to your doctor. Do not stop taking Trintellix (Vortioxetine) without consulting your doctor.

Do not give Trintellix (Vortioxetine) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Trintellix (Vortioxetine) if their doctor has not prescribed it.

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Trintellix Dosage

The recommended dose of Trintellix (Vortioxetine) for adults less than 65 years of age is 10 mg taken once daily. For adults 65 years of age or older the starting dose is 5 mg taken once daily. Depending on how well it works for you and the level of side effects you experience, your doctor may suggest that you increase the dose to a maximum of 20 mg daily.

Trintellix (Vortioxetine) may be taken with or without food.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Trintellix (Vortioxetine) exactly as prescribed by your doctor.

If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Trintellix (Vortioxetine) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Trintellix Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Trintellix (Vortioxetine). If you are concerned about side effects, discuss the risks and benefits of Trintellix (Vortioxetine) with your doctor.

The following side effects have been reported by at least 1% of people taking Trintellix (Vortioxetine). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abnormal dreams
  • cold and flu symptoms (e.g., sore throat, runny nose, nasal congestion, cough, Fever)
  • Constipation
  • decreased appetite
  • Diarrhea
  • dizziness
  • drowsiness
  • dry eyes
  • Dry Mouth
  • fatigue
  • increased sweating
  • itchiness
  • muscle twitching
  • nausea
  • nightmares
  • night sweats
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal swelling
  • agitation
  • back or joint pain
  • feelings of paranoia
  • mood swings
  • muscle pain or weakness
  • new or worsening signs of depression (such as feeling sad, losing interest in things you used to enjoy, weight changes, changes in sleep habits, feelings of guilt or worthlessness, thoughts of suicide)
  • signs of bleeding (e.g., bloody nose, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
  • symptoms of Glaucoma (e.g., eye pain, blurred vision)
  • symptoms of low blood sodium (confusion, seizures, drowsiness, dryness of mouth, increased thirst, lack of energy)
  • symptoms of mania (e.g., talking, feeling, and acting with excitement and activity you cannot control)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • seizure or convulsions
  • signs of serotonin syndrome (e.g., agitation, confusion, diarrhea, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking, twitching)
  • signs of a Anaphylaxis (severe allergic reaction) (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of bleeding in the stomach (e.g., bloody, black, or tarry stools; spitting up of blood; vomiting blood or material that looks like coffee grounds)
  • thoughts of suicide or hurting yourself

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Trintellix (Vortioxetine).

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Trintellix Available Form

5 mg
Each pink, almond-shaped, biconvex film-coated tablet engraved with "TL" on one side and "5" on the other side contains 6.355 mg of Trintellix (Vortioxetine) hydrobromide equivalent to 5 mg of Trintellix (Vortioxetine). Nonmedicinal ingredients: hydroxypropylcellulose, hypromellose, iron oxide red, Macrogol 400, magnesium stearate, mannitol, microcrystalline cellulose, sodium starch glycolate (Type A), and titanium dioxide (E 171).

10 mg
Each yellow, almond-shaped, biconvex, film-coated tablet engraved with "TL" on one side and "10" on the other side contains 12.71 mg of Trintellix (Vortioxetine) hydrobromide equivalent to 10 mg of Trintellix (Vortioxetine). Nonmedicinal ingredients: hydroxypropylcellulose, hypromellose, iron oxide yellow, Macrogol 400, magnesium stearate, mannitol, microcrystalline cellulose, sodium starch glycolate (Type A), and titanium dioxide (E 171).

15 mg
Each orange, almond-shaped, biconvex, film-coated tablet engraved with "TL" on one side and "15" on the other side contains 19.065 mg of Trintellix (Vortioxetine) hydrobromide equivalent to 15 mg of Trintellix (Vortioxetine). Nonmedicinal ingredients: hydroxypropylcellulose, hypromellose, iron oxide red, iron oxide yellow, Macrogol 400, magnesium stearate, mannitol, microcrystalline cellulose, sodium starch glycolate (Type A), and titanium dioxide (E 171).

20 mg
Each red, almond-shaped, biconvex, film-coated tablet engraved with "TL" on one side and "20" on the other side contains 25.42 mg of Trintellix (Vortioxetine) hydrobromide equivalent to 20 mg of Trintellix (Vortioxetine). Nonmedicinal ingredients: hydroxypropylcellulose, hypromellose, iron oxide red, Macrogol 400, magnesium stearate, mannitol, microcrystalline cellulose, sodium starch glycolate (Type A), and titanium dioxide (E 171).

Trintellix Contraindications

Do not take Trintellix (Vortioxetine) if you:

  • are allergic to Trintellix (Vortioxetine) or any ingredients of the medication
  • are taking an MAO inhibitor (e.g., Phenelzine, Tranylcypromine, Moclobemide) or have taken an MAO inhibitor within the past 2 weeks (do not start treatment with an MAO inhibitor until at least 3 weeks after stopping Trintellix (Vortioxetine) treatment)

Automatic Refills

We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.

Trintellix Precautions

There may be an interaction between Trintellix (Vortioxetine) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Trintellix (Vortioxetine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Trintellix Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Trintellix (Vortioxetine).

Abnormal bleeding: Trintellix (Vortioxetine), like other similar medications, may cause abnormal bleeding, including bleeding in the stomach or intestines. People who have or have had a history of bleeding disorders should discuss with their doctor how Trintellix (Vortioxetine) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed.

Report any unusual bruising or bleeding to your doctor, especially if you are taking other medications that affect blood clotting. These medications include acetylsalicylic acid (Asa), Clopidogrel, Dipyridamole, nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., Ibuprofen or Naproxen), other anticoagulant medications (e.g., Warfarin), and certain antipsychotic medications.

Bone health: Like other similar medications, Trintellix (Vortioxetine) may increase the risk of bone fracture, especially if you are a senior or have Osteoporosis or other major risk factors for breaking a bone. Your doctor may monitor your bones while you are taking Trintellix (Vortioxetine).

Drowsiness/reduced alertness: Although Trintellix (Vortioxetine) is not known to cause drowsiness, avoid driving, operating machinery, or performing other hazardous tasks until you have determined how Trintellix (Vortioxetine) affects you.

Glaucoma: Trintellix (Vortioxetine) can cause an increase in the pressure in the eye, making symptoms of glaucoma worse. If you have narrow-angle glaucoma, discuss with your doctor how Trintellix (Vortioxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed.

Liver function: Liver disease or reduced liver function may cause Trintellix (Vortioxetine) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Trintellix (Vortioxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Trintellix (Vortioxetine).

Trintellix (Vortioxetine) is not recommended for people with severe liver disease.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Mania: Trintellix (Vortioxetine) may cause symptoms of mania to worsen or return. If you have a history of mania or bipolar disorder, discuss with your doctor how Trintellix (Vortioxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed.

Seizures: Medications to treat depression may cause an increased risk of seizures. If you have a history of seizures, discuss with your doctor how Trintellix (Vortioxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed. Anyone who develops seizures should seek immediate medical attention.

Serotonin syndrome: Severe reactions are possible when Trintellix (Vortioxetine) is combined with other medications that act on serotonin, such as tricyclic antidepressants, "triptan" medications for migraine, and some medications to treat nausea due to chemotherapy. These combinations should be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, and changes in mental state including delirium and agitation. Coma and death are possible.

If you are taking other medications that affect serotonin, discuss with your doctor how Trintellix (Vortioxetine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trintellix (Vortioxetine), and whether any special monitoring is needed.

Stopping the medication: Stopping Trintellix (Vortioxetine) suddenly may lead to side effects such as dizziness, abnormal dreams, numbness or tingling sensations, agitation, anxiety, nausea, vomiting, sweating, or other symptoms. If you are thinking of stopping the medication, check with your doctor first. Your doctor may want you to decrease the dose of the medication gradually when it is time to stop taking Trintellix (Vortioxetine).

Suicidal or agitated behaviour: People taking Trintellix (Vortioxetine) may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. These behavioural changes may be more likely to occur in children and adolescents, but they are possible for all age groups that use Trintellix (Vortioxetine). These symptoms may occur within several weeks after starting Trintellix (Vortioxetine). If you experience these side effects or notice them in a family member who is taking Trintellix (Vortioxetine), contact your doctor immediately. You should be closely monitored by your doctor for emotional and behaviour changes while taking Trintellix (Vortioxetine).

Pregnancy: Trintellix (Vortioxetine) should not be used during pregnancy unless the benefits outweigh the risks. It has also been reported that babies born to women who took medications similar to Trintellix (Vortioxetine) during the last trimester of their pregnancy may experience adverse effects (such as breathing problems, seizures, trouble feeding, vomiting, low blood sugar, shaking, jitteriness, irritability, and constant crying) that result in an increase in the length of hospital stay. If you become pregnant while taking Trintellix (Vortioxetine), contact your doctor immediately.

Breast-feeding: Trintellix (Vortioxetine) passes into breast milk. If you are a breast-feeding mother and are taking Trintellix (Vortioxetine), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Trintellix (Vortioxetine) for people less than 18 years of age have not been established. The use of Trintellix (Vortioxetine) by children and adolescents less than 18 years old may cause behavioural and emotional changes, such as suicidal thoughts and behaviour.

Seniors: There is limited information about the safety of seniors using Trintellix (Vortioxetine). If you are over 65 and using Trintellix (Vortioxetine), lower doses are recommended.

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References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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