Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Clomid (Clomiphene). If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking Clomid (Clomiphene). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal bloating
• breast discomfort
• Constipation
• Diarrhea
• dizziness or lightheadedness
• hair loss
• headache
• heavy menstrual periods or bleeding between periods
• hot flashes
• increased appetite
• increased menstrual pain
• itchiness
• nausea or vomiting (not severe or continuing)
• nervousness
• sensation of spinning
• tiredness
• trouble sleeping
• vaginal dryness
• weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abdominal or lower stomach pain
• blurred vision
• Cataracts
• double or decreased vision, or other vision problem
• fast, pounding or irregular heartbeat
• occurrences of "flashes of light"
• sensitivity of eyes to light
• signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
• sudden and severe Headaches
• symptoms of liver problems (e.g., yellow eyes or skin, abdominal pain, poor appetite, dark urine, or pale stools)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, Fever, chills, rapid heartbeat, swollen abdomen)
• signs of Stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)
• symptoms of a Anaphylaxis (severe allergic reaction) (Hives, shortness of breath, swelling of the face or throat)
• symptoms of ovarian hyperstimulation syndrome (difficulty breathing, abdominal or pelvic pain or discomfort, bloating, nausea, vomiting, diarrhea, decreased amount of urine, rapid weight gain)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Clomid (Clomiphene).

Each white, rounded, flat-faced, bevelled-edge, compressed tablet, scored on one side with "Clomid" marked above the score and "50" below, contains 50 mg of Clomid (Clomiphene) citrate USP. Nonmedicinal ingredients: cornstarch, lactose monohydrate, magnesium stearate, pregelatinized starch, and sucrose.

Do not take Clomid (Clomiphene) if you:

• are allergic to Clomid (Clomiphene) or any ingredients of the medication
• are pregnant
• have a hormone-dependent tumour (tumours that can be stimulated to grow by sex hormones such as estrogen)
• have abnormal vaginal bleeding of unknown cause
• have fibroid tumours of the uterus
• have liver disease or have had reduced liver function in the past
• have ovarian cysts (not associated with polycystic ovary)
• have Thrombophlebitis (inflammation of a vein with formation of a blood clot)
• have Depression

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Clomid (Clomiphene).

Ectopic Pregnancy: There is an increased chance of ectopic pregnancy (i.e., the baby develops in one of the fallopian tubes instead of in the uterus) in women who conceive following Clomid (Clomiphene) therapy. It is important to have an early ultrasound to ensure that the baby is developing inside the uterus.

Following instructions: It is extremely important to understand your treatment and to follow instructions closely. Be sure to ask your doctor any questions you might have.

Multiple births: Clomid (Clomiphene) can cause multiple follicles to mature and release more than one egg in a cycle. This in turn, increases the possibility of multiple births. The incidence of multiple pregnancy (including twins, triplets, quadruplets, and quintuplets) can be up to 10 times greater when conception occurs during a cycle in which Clomid (Clomiphene) therapy is taken.

Ovarian cysts: With Clomid (Clomiphene) therapy, there is the possibility of ovarian cyst formation. Women should notify their doctor of any abdominal or pelvic pain, weight gain, discomfort, or bloating after taking Clomid (Clomiphene).

Ovarian enlargement and ovarian hyperstimulation syndrome (OHSS): These conditions may occur with Clomid (Clomiphene) therapy. Early warning signs include abdominal or pelvic pain, bloating, nausea, vomiting, diarrhea, and weight gain. Notify your doctor immediately if any of these symptoms occur after taking Clomid (Clomiphene).

Women with ovarian hyperstimulation syndrome (OHSS) may also have difficulty breathing and pass decreased amounts of urine. Your doctor will conduct regular pelvic examinations between 2 and 3 weeks after starting each course of therapy.

Vision changes: Blurring of vision or other sight problems (such as afterimages, spots, flashes, double vision, or sensitivity to light) may occasionally occur while taking Clomid (Clomiphene) or shortly after therapy finishes. These types of sight problems may make it more dangerous to drive or operate machinery, particularly under conditions where light varies. If you experience such effects, stop taking the medication and contact your doctor.

Pregnancy: Clomid (Clomiphene) should not be taken during pregnancy.

Breast-feeding: It is not known if Clomid (Clomiphene) passes into breast milk. If you are a breast-feeding mother and are taking Clomid (Clomiphene), it may affect your baby. Clomid (Clomiphene) may also reduce the amount of milk produced by breast-feeding mothers. Talk to your doctor about whether you should continue breast-feeding.

Children: Clomid (Clomiphene) is intended for use by women of childbearing age and therefore, the safety and effectiveness of Clomid (Clomiphene) have not been established for children.

Seniors: Clomid (Clomiphene) is intended for use by women of childbearing age and therefore, the safety and effectiveness of this medication have not been established for seniors.