Diclectin belongs to the class of medications called antinauseants. Diclectin is used to treat the nausea and vomiting of pregnancy. It contains two medications, doxylamine succinate and pyridoxine hydrochloride, that work on the centers in the brain that control these symptoms.

Diclectin may be available under multiple brand names and/or in several different forms. Any specific brand name of Diclectin may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Diclectin may not be used for all of the conditions discussed here.

Your doctor may have suggested Diclectin for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Diclectin, speak to your doctor. Do not stop taking Diclectin without consulting your doctor.

Do not give Diclectin to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Diclectin if their doctor has not prescribed it.

The recommended dose is 2 tablets at bedtime. In severe cases or if nausea or vomiting occurs during the day, your doctor may recommend adding 1 tablet in the morning and 1 tablet mid-afternoon. Swallow the medication whole. Do not chew, divide, or crush the tablets.

Diclectin works best when taken 4 to 6 hours before needed (e.g., anticipated Morning Sickness) and should be taken on a daily basis.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Diclectin exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Diclectin at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Diclectin. If you are concerned about side effects, discuss the risks and benefits of Diclectin with your doctor.

The following side effects have been reported by at least 1% of people taking Diclectin. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Diarrhea
• difficulty sleeping
• dizziness
• headache
• irritability
• nervousness
• sleepiness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• disorientation
• pounding, irregular heartbeat
• stomach pain
• trouble with urinary flow

Stop taking the medication and seek immediate medical attention if any of the following occur:

• convulsions (seizures)
• signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Diclectin.

Each white, film-coated, delayed-release tablet imprinted with the pink image of a pregnant woman contains 10 mg of doxylamine succinate and 10 mg of pyridoxine hydrochloride. Nonmedicinal ingredients: ammonium hydroxide, n-butyl-alcohol, carnauba wax powder, colloidal silicon dioxide, croscarmellose sodium, FD&C Red No. 27, denatured alcohol, FD&C Blue No. 2, hypromellose, isopropyl alcohol, magnesium stearate, magnesium trisilicate, methacrylic copolymer acid, microcrystalline cellulose 102, PEG 400, PEG 8000, polysorbate 80, propylene glycol, shellac glaze, simethicone, sodium bicarbonate, sodium lauryl sulfate, talc, titanium dioxide and triethyl citrate. Gluten-, lactose-, sulfite-, and tartrazine-free.

Do not take Diclectin if you:

• are allergic to doxylamine succinate, pyridoxine hydrochloride, or any ingredients of the medication.
• are at risk of having an Asthma attack
• have narrow angle Glaucoma
• have a peptic ulcer (stomach ulcer)
• have a blockage in the digestive tract
• have urinary tract problems
• are taking monoamine oxidase inhibitors (e.g., certain antidepressants, Linezolid, selegilene, methylene blue)

There may be an interaction between doxylamine succinate – pyridoxine HCl and any of the following:

• aclidinium
• alcohol
• amphetamines (e.g., Dextroamphetamine, lisdexamphetamine)
• antihistamines (e.g., cetirizine, doxylamine, Diphenhydramine, Hydroxyzine, Loratadine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• atropine
• azelastine
• barbiturates (e.g., butalbital, pentobarbital, Phenobarbital)
• benzodiazepines (e.g., Alprazolam, Diazepam, Lorazepam)
• belladonna
• Benztropine
• Betahistine
• brimonidine
• Buprenorphine
• Buspirone
• cannabis
• chloral hydrate
• Cyclobenzaprine
• Darifenacin
• Disopyramide
• Domperidone
• Donepezil
• efavirenz
• Flavoxate
• Galantamine
• Glucagon
• glycopyrrolate
• hyaluronidase
• ipratropium
• ketotifen
• levodopa
• magnesium sulfate
• Mirabegron
• Mirtazapine
• monoamine oxidase inhibitors (M.O.S. e.g. Maprotiline, Moclobemide, Selegiline, Phenelzine, Rasagiline, Tranylcypromine)
• Nabilone
• narcotic medications (e.g., Morphine, Codeine, Fentanyl, Oxycodone)
• Olopatadine
• orphenadrine
• Oxybutynin
• potassium chloride
• Pramipexole
• Rivastigmine
• Ropinirole
• Rotigotine
• scopolamine
• secretin
• seizure medications (e.g., Carbamazepine, Clobazam, Levetiracetam, phenobarbital, Phenytoin, primidone, Topiramate, Valproic acid, zonisamide)
• selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
• sodium oxybate
• Solifenacin
• thiazide diuretics (water pills; e.g., Hydrochlorothiazide, Indapamide, Metolazone)
• tiotropium
• Tolterodine
• Tramadol
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Desipramine, Trimipramine)
• umeclidinium
• Zolpidem
• Zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Diclectin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.