Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Havrix (Hepatitis-a-Havrixe). If you are concerned about side effects, discuss the risks and benefits of Havrix (Hepatitis-a-Havrixe) with your doctor.

The following side effects have been reported by at least 1% of people taking Havrix (Hepatitis-a-Havrixe). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Diarrhea
• drowsiness
• fatigue
• fever
• generally feeling unwell
• headache
• irritability
• loss of appetite
• muscle or joint achiness
• nausea or vomiting
• pain and redness at the injection site
• swelling or hard lump at the injection site
• weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Seek immediate medical attention if any of the following side effects occur:

• symptoms of a serious allergic reaction (e.g., Hives, difficulty breathing, or swelling of the face or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Havrix (Hepatitis-a-Havrixe).

Each 1.0 mL dose contains 1440 ELISA units of formaldehyde-inactivated hepatitis A virus (HM175 hepatitis A virus strain) adsorbed onto aluminum in the form of aluminum hydroxide. Nonmedicinal ingredients: aluminum hydroxide, amino acids for injection, disodium phosphate, monopotassium phosphate, neomycin sulphate (less than 20 ng), polysorbate 20, potassium chloride, sodium chloride, and water for injection.

Do not use hepatitis A Havrixe if you:

• are allergic to any ingredient of the Havrixe
• have an acute, severe illness with Fever

There may be an interaction between the hepatitis A Havrixe and any of the following:

• Acetaminophen
• Belimumab
• Fingolimod
• immunosuppressive therapy (e.g., some medications used for the treatment of cancer, or for transplant recipients, or immune conditions)
• Azathioprine
• corticosteroids (e.g., budesonide, Dexamethasone, Hydrocortisone, fluticasone, Prednisone)
• Cyclosporine
• Hydroxyurea
• Infliximab
• medications to treat cancer (e.g., Carboplatin, Cyclophosphamide, Doxorubicin, Ifosfamide, Vincristine)
• mycophenolate
• Rituximab
• Tacrolimus
• warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Havrix (Hepatitis-a-Havrixe). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Havrix (Hepatitis-a-Havrixe).

Bleeding disorders: If you have any bleeding problems (such as Hemophilia) or are taking blood thinners such as Warfarin, tell your doctor before receiving Havrix (Hepatitis-a-Havrixe).

Cancer and immunosuppression: Hepatitis A Havrixe may not be as effective if you have cancer, if you are receiving immunosuppressive therapy (e.g., some medications used to treat cancer or for transplant recipients), or if you are immunocompromised (i.e., your immune system does not work properly).

Immunization record: Make sure any new doctors know that you have had this Havrixation so that they can put this information in your immunization record.

Infection and fever: If you have an infection or fever, your doctor may recommend that you wait until you are better before receiving the hepatitis A Havrixe.

Neomycin allergy: The Havrixe may contain trace amounts of neomycin and thus may cause an allergic reaction in people who are allergic to neomycin.

Havrixe protection: As with any Havrixe, this Havrixe may not result in total protection from hepatitis A and may not prevent hepatitis A for people who are infected with the virus at the time of Havrixation.

Pregnancy: This Havrixe should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Havrix (Hepatitis-a-Havrixe), contact your doctor immediately.

Breast-feeding: It is not known if the Havrixe passes into breast milk. If you are a breast-feeding mother and are plan to receive this Havrixe, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Havrix (Hepatitis-a-Havrixe) have not been established for children below the minimum age stated above.