Kalydeco

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Available Form:  

TABLET

Manufacturer name:  

Vertex

Generic name:  

IVACAFTOR

Strength:  

150MG

What is Kalydeco?

Kalydeco (Ivacaftor) belongs to the class of medications called Cystic Fibrosis transmembrane conductance regulator (CFTR) potentiators. It is used to treat cystic fibrosis (CF) in adults and children over the age of 2 who have one of several possible mutations (a change) in their CFTR gene.

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Kalydeco Price and Cost Calculator

How much does Kalydeco cost?

  • The cost of Kalydeco is $0 with us here at PocketPills. The cost of Kalydeco can be lower if your insurance covers it. To calculate the total price of purchasing Kalydeco, you should also consider dispensing and delivery fees.

How much is the dispensing fee for Kalydeco

  • The dispensing cost to order Kalydeco with us is only $0. Pocketpills aims to offer you the most affordable Kalydeco price in Canada.
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Kalydeco 

Indication

Kalydeco (Ivacaftor) belongs to the class of medications called Cystic Fibrosis transmembrane conductance regulator (CFTR) potentiators. It is used to treat cystic fibrosis (CF) in adults and children over the age of 2 who have one of several possible mutations (a change) in their CFTR gene. It is also used in people over the age of 18 who have the R117H mutation. It is not effective for people with CF who have the mutation delta F508.

In CF, an abnormal protein called CFTR is produced. This protein changes the way chloride (a component of salt, which is also called sodium chloride) moves in and out of cells. This affects the balance between salt and water in the body, making the mucus that lines the lungs, pancreas, and other organs thicker and stickier. Kalydeco (Ivacaftor) allows more chloride to be moved and improves the balance between salt and water.

Kalydeco (Ivacaftor) may be available under multiple brand names and/or in several different forms. Any specific brand name of Kalydeco (Ivacaftor) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Kalydeco (Ivacaftor) may not be used for all of the conditions discussed here.

Your doctor may have suggested Kalydeco (Ivacaftor) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Kalydeco (Ivacaftor), speak to your doctor. Do not stop taking Kalydeco (Ivacaftor) without consulting your doctor.

Do not give Kalydeco (Ivacaftor) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Kalydeco (Ivacaftor) if their doctor has not prescribed it.

Kalydeco 

Dosage

The usual dose for adults and children (over the age of 6 years and weighing more than 25 kg), is 150 mg twice a day (morning and evening about 12 hours apart) with a fat-containing food. Fat-containing food helps get the right amount of medication into your body. Examples include meals or foods prepared with butter or oils, eggs, cheeses, nuts, whole milk, or meats. Meals and snacks recommended in CF guidelines contain the right amounts of fat.

The usual dose for children between the ages of 2 years and 6 years is based on body weight. Oral granules are available for children ages 2 years and older, or individuals who have difficulty swallowing tablets. The granules may be sprinkled on soft foods or liquids (excluding grapefruit juice) and consumed within 1 hour. The granules should be consumed with or immediately after a fat-containing food.

Tablets should be swallowed whole with fluids and not chewed, crushed, or dissolved.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that Kalydeco (Ivacaftor) be taken exactly as prescribed by your doctor.

If you miss a dose by less than 6 hours, take the missed dose with fat-containing food, and continue with your regular schedule. If you miss a dose by 6 or more hours, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Kalydeco (Ivacaftor) at room temperature, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Kalydeco 

Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Kalydeco (Ivacaftor). If you are concerned about side effects, discuss the risks and benefits of Kalydeco (Ivacaftor) with your doctor.

The following side effects have been reported by at least 1% of people taking Kalydeco (Ivacaftor). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Diarrhea
  • dizziness
  • headache
  • joint pain
  • nausea
  • pain in your stomach
  • symptoms of an upper respiratory tract infection (The Common Cold) such as sore throat, nasal or sinus congestion, or a runny nose

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • rash
  • signs and symptoms of a liver disorder such as yellowing skin or eyes, dark urine, stomach pain, nausea, vomiting, loss of appetite, pale stools, or itchy skin
  • symptoms of low blood sugar (e.g., nervousness, sweating, faintness, fast heartbeat, nausea, tingling, trembling)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • allergic reactions such as rash, Hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Kalydeco (Ivacaftor).

Kalydeco 

Available form

Tablet

Each light-blue, capsule-shaped tablet, printed with "V 150" in black ink on one side, contains 150 mg of Kalydeco (Ivacaftor). Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, hypromellose acetate succinate, indigo carmine aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, Peg 3350, polyvinyl alcohol, sodium lauryl sulfate, talc, and titanium dioxide. Printing ink: ammonium hydroxide, iron oxide black, propylene glycol, and shellac.

Oral Granules

50 mg
Each packet of white-to-off-white, sweetened, unflavoured granules contains 50 mg of Kalydeco (Ivacaftor). Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hypromellose acetate succinate, lactose monohydrate, magnesium stearate, mannitol, sucralose and sodium lauryl sulfate.

75 mg
Each packet of white-to-off-white, sweetened, unflavoured granules contains 75 mg of Kalydeco (Ivacaftor). Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, hypromellose acetate succinate, lactose monohydrate, magnesium stearate, mannitol, sucralose and sodium lauryl sulfate.

Kalydeco 

Contraindications

Do not take Kalydeco (Ivacaftor) if you are allergic to Kalydeco (Ivacaftor) or any ingredients of the medication.

Kalydeco 

Precautions

There may be an interaction between Kalydeco (Ivacaftor) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Kalydeco (Ivacaftor). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Kalydeco 

Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Kalydeco (Ivacaftor).

Cataracts: Cataracts have been reported in children treated with Kalydeco (Ivacaftor). Your doctor may recommend eye examinations before and during treatment with Kalydeco (Ivacaftor).

Dizziness: Kalydeco (Ivacaftor) can cause dizziness. Do not drive or operate machinery until you are certain that Kalydeco (Ivacaftor) does not affect your ability to do these activities safely.

Grapefruit juice: Grapefruit juice can increase the levels of Kalydeco (Ivacaftor) in the body, causing side effects. Avoid consuming food or beverages containing grapefruit or Seville oranges while you are taking Kalydeco (Ivacaftor).

Kidney function: The safety and effectiveness of Kalydeco (Ivacaftor) have not been established for people with decreased kidney function or end-stage Kidney Disease. If you have decreased kidney function or kidney disease, discuss with your doctor how Kalydeco (Ivacaftor) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Kalydeco (Ivacaftor), and whether any special monitoring is needed.

Liver function: Liver disease or reduced liver function may cause Kalydeco (Ivacaftor) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Kalydeco (Ivacaftor) may affect your medical condition and how your medical condition may affect the dosing and effectiveness of Kalydeco (Ivacaftor). Your doctor will perform regular tests to check your liver function while you are taking Kalydeco (Ivacaftor).

Pregnancy: The safety and effectiveness of Kalydeco (Ivacaftor) have not been established for women who are pregnant. Kalydeco (Ivacaftor) should not be used during pregnancy unless the benefits outweigh the risks. Talk to your doctor if you become pregnant while taking Kalydeco (Ivacaftor).

Breast-feeding: It is not known whether Kalydeco (Ivacaftor) passes into breast milk. If you are a breast-feeding mother and are taking Kalydeco (Ivacaftor), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Kalydeco (Ivacaftor) have not been established for children less than 2 years old.

Seniors: The safety and effectiveness of Kalydeco (Ivacaftor) have not been established for seniors 65 years of age and older.

Kalydeco frequently asked questions

How To Buy Kalydeco Online?

You can buy Kalydeco online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Kalydeco?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Kalydeco in Canada?

Shipping cost for Kalydeco to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Kalydeco delivered to my home?

You could get Kalydeco delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Kalydeco in Canada for free?

You can get Kalydeco for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Kalydeco for free.

Can I consult a doctor online to get Kalydeco?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Kalydeco.

Can I buy Kalydeco without a prescription?

You need a valid prescription to buy Kalydeco from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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