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Buy Mektovi Online in Canada

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Looking to buy Mektovi online? Get your medications delivered to your doorstep. Just upload your prescription, consult with our pharmacists and we will deliver your daily medications right to your doorstep. Just looking for medication prices - search medication prices

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Need an online prescription for Mektovi? Talk to a Canadian Doctor for free. Get online prescriptions, renewals, or even request a new one. Book Your appointment today!

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Frequently Asked Questions About Mektovi

What is Mektovi?

Mektovi is an oral prescription medication used along with other medications of similar action to treat various types of cancers, especially skin cancer.

This medication was recently approved in Canada on 31st March 2021.

How to use Mektovi?

What are some Mektovi label uses?

Mektovi or Binimetinib is used in the treatment of melanoma (a type of skin cancer)

  • With a certain type of abnormal BRAF gene (V600E or V600K mutation)
  • That is spread to other organs or body parts or cannot be removed through surgery.

What are some Mektovi off-label uses?

There is no off-label use of the medicine so far.

Mektovi may be prescribed for other uses; ask your doctor or pharmacist for more information.

Mektovi Direction For Use

  • Mektovi is an oral medication and is available in tablet form. The tablet is available in 15 mg strength. It is a yellow/dark yellow colored tablet
  • It can be taken with or without food twice daily, approximately 12 hours of gap between the two doses
  • Take the medication around the same time every day
  • Follow the instructions given by your physician or pharmacist. Read the prescription label carefully for the dosing instructions
  • If you vomit the medication, do not take another dose. Follow your regular dosing schedule
  • If you miss your dose, it should be administered as soon as possible without waiting until the next scheduled dose. However, if it is within 6 hours of the next dose, skip the missed dose and continue your regular schedule. Do not take a double dose. 

The recommended dose of Mektovi is 45 mg orally twice daily along with Braftovi for treatment of unresectable or metastatic melanoma with a BRAF V600E or V600K mutation. For patients with moderate or severe liver disorders, the recommended dose is 30 mg twice orally twice daily. 

Ingredients And Benefits in Mektovi

Binimetinib is the primary ingredient of Mektovi. 

Mektovi belongs to the kinase inhibitors class of medications. It works by stopping the action of an abnormal protein that is responsible for signaling cancer cells to multiply. Thus, helping to stop or slow the spread of cancer cells.   

Mektovi is used to treat unresectable or metastatic melanoma with a BRAF V600E or V600K mutation with other medications. It is used in combination with Braftovi for the treatment. 

Warnings and Precautions when taking Mektovi

  • Inform your health worker about other prescription and non-prescription medications that you are taking. Also, inform about vitamins, herbal and nutritional supplements that you are taking or planning to take
  • Mektovi should not be used in the treatment of patients with wild-type BRAF melanoma or wild CRC
  • Your doctor may reduce, suspend your dosing temporary or permanently if you experience any side effects. Be sure to tell your physician about how you feel during the treatment
  • You also may be at risk of bleeding 
  • Perform ophthalmologic evaluations at regular intervals and for any visual disturbances as you may be at risk for Uveitis (inflammation of the eye)
  • You should assess left ventricular ejection fraction before you initiate treatment and one month of treatment, followed every 2 to 3 months after that
  • You may be at risk for deep vein thrombosis and pulmonary embolism
  • Assess yourself for interstitial lung disease in case of respiratory symptoms
  • Monitor liver function before and during the treatment
  • Monitor creatinine and creatine phosphokinase periodically
  • You also may be at risk of hemorrhage 

Storage and Disposal of Mektovi

  • It should be refrigerated at 20ºC to 25ºC
  • Dispense the medication in the original bottle.
  • Always keep the lid of the bottle tightly closed.
  • Keep the tablets away from heat and moisture
  • Keep it away from reach and sight of children 

Contraindications of Mektovi

Inform your healthcare provider in case of an allergy to Mektovi or any other medication or any of the ingredients in Mektovi. Ask your pharmacist or check the medication guide for a list of the ingredients.

Do not take the medicine or inform your doctor before taking it if you have or had following conditions;

  • Heart failure 
  • Liver disease
  • Cardiomyopathy
  • Venous thromboembolism
  • Interstitial Lung disease  

Besides, inform your doctor if you are pregnant or breastfeeding, or planning to be pregnant. You should use birth control to prevent pregnancy during your treatment with Mektovi and for 30 days after your final dose. If you become pregnant while you are on treatment with Mektovi, call your physician immediately since Mektovi may harm your fetus.

Do not breastfeed while you are on treatment with Mektovi and for three days after your final dose. 

Interactions with Mektovi

Mektovi may interact with imunosupressants and other medicines. Some examples include:

  • Amiodarone 
  • Carbamazepine
  • Citalopram
  • Clarithromycin 
  • Diltiazem
  • Nevirapine
  • Phenytoin 
  • Phenobarbital 
  • Quinidine 
  • Procainamide 
  • Ketoconazole
  • Modafinil 
  • Rifampin 
  • Sotalol
  • Verapamil 
  • St John’s Wort

This may not be a complete list of medications. You must inform all the medicines that you are taking or are going to take. Always consult your physician before starting any new medication. 

What are Mektovi Side Effects ?

Like all the medications, Mektovi also has side effects. It is possible that you may experience some of the side effects. Inform your physician if these symptoms do not go away or are severe:

  • Abdominal pain
  • Fatigue
  • Dizziness
  • Diarrhea 
  • Constipation 
  • Nausea
  • Vomiting

Some of these effects can be serious. If you experience any of the following symptoms, you must inform your physician immediately or get emergency treatment:

  • Vision changes 
  • Eye pain
  • Swelling in eyes
  • Redness in eyes 
  • Cough
  • Chills
  • Sore throat 
  • Fever or other signs of infections
  • Muscle pain
  • Unusual weakness
  • Dark red or brown urine
  • Sudden onset of breathing difficulty 
  • Chest pain 
  • Fast heartbeat
  • Shortness of breath 
  • Swelling of ankles, lower legs, ankles, or feet
  • Leg pain 
  • Unusual bleeding
  • Unusual bruising
  • Coughing up blood
  • Discomfort in the stomach area 
  • Loss of appetite 

This is not a complete list of side effects. If you experience severe side effects or symptoms that are persistent, please contact your doctor immediately.

How is Mektovi Taken?

It is available as an oral medicine to be taken once at the same time every day. You can take it with or without food.

Is There A Generic Version of Mektovi?

No. For now, there is no generic version of Mektovi available in Canada.

Who Makes This Drug and What Is Their Manufacturing Record of Success?

Pfizer, a global biopharmaceutical company, makes Mektovi. They aim to provide health for all by manufacturing advanced breakthrough products. 

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