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Buy Phesgo Online in Canada

Get FREE Delivery, Competitive Prices and Low Dispensing Cost

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Looking to buy Phesgo online? Get your medications delivered to your doorstep. Just upload your prescription, consult with our pharmacists and we will deliver your daily medications right to your doorstep. Just looking for medication prices - search medication prices

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Need an online prescription for Phesgo? Talk to a Canadian Doctor for free. Get online prescriptions, renewals, or even request a new one. Book Your appointment today!

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Get an Phesgo Prescription Online

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Need an online prescription for Phesgo? Talk to a Canadian Doctor for free. Get online prescriptions, renewals, or even request a new one. Book Your appointment today!

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No more waiting in line, sorting your pills, or missing your doses - Switch to PocketPills' online pharmacy delivery service. Your medication is sorted by dose, date and time into PocketPacks, convenient to carry whenever on the go Manage everything directly through our app.

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Chat with our Pharmacists about Phesgo

Have a question about Phesgo? Ask any questions about medications, ailments, side-effects via live chat, SMS, phone or email to assist you

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Chat with our Pharmacists about Phesgo

Have a question about Phesgo? Ask any questions about medications, ailments, side-effects via live chat, SMS, phone or email to assist you

Frequently Asked Questions About Phesgo

What is Phesgo?

Phesgo is a newer treatment for managing a specific type of breast cancer known as HER2-positive breast cancer.

These cancer types are prevalent, and about one in five women are suffering from them. The name comes from the protein HER2 on cancer cells. These cells tend to spread and grow aggressively. 

Phesgo is one of its kind as it has two monoclonal antibodies that work by blocking the chemicals signaling cancer cells to grow.

Let’s understand more about the medication, including its uses, side effects, and precautions to be followed.

What is Phesgo used for?

What are some Phesgo label uses?

Phesgo is a combination of two monoclonal antibodies, pertuzumab and trastuzumab and hyaluronidase.

The medicine is used for:

  • Metastasized cancer (cancer cells that are spread to other body parts such as the lungs and liver) or the cancer cells have come back to the breast and the surrounding areas but cannot be operated on (unresectable), or no chemotherapy or medicines that attach to HER2 have been given.
  • Cancer cells have not spread to other body parts, and the treatment will be before surgery or after surgery.

What are some Phesgo off-label uses?

There is no off-label use of the medicine so far.

The medication may be prescribed for other uses; ask your physician or pharmacist for detailed information.

Dosage and Directions for Use of Phesgo

  • Phesgo is available as a solution to be given subcutaneously (under the skin).
  • A doctor or a nurse will give you the injection once every three weeks.
  • They will give the injection in alternate thighs every time.
  • Your healthcare provider will ensure that the injection is given at a new place at least 2.5 cm away from the previous site of injection.
  • Do not stop going for the treatment without consulting your doctor. 
  • Taking the entire course of Phesgo at the right time every three weeks also determines how well your chemotherapy will act.

Starting of the treatment:

  • Usually, Phesgo 1200 mg/600 mg will be given for over eight minutes. The doctor will monitor your reaction during the process of injecting the medicine and 30 minutes after it.
  • They will also give you chemotherapy.

Subsequent injections:

  • Usually, Phesgo 600 mg/600 mg will be given over five minutes. The doctor will monitor your reaction during the process of injecting the medicine and 15 minutes after it.
  • They will also give you chemotherapy.

The number of injections will depend on:

  • Your response to the treatment
  • Whether you are having the treatment before or after the surgery.

If you forget to have Phesgo:

  • If you miss or forget the treatment, make the appointment as soon as possible.
  • Your doctor will decide the dose of Phesgo based on the time elapsed between two visits.

Storage and Disposal of Phesgo

  • The vials are to be stored in the refrigerator at 2ºC to 8ºC in the original carton.
  • The vials are to be protected from direct sunlight until the time of reconstitution.  
  • Do not freeze the reconstituted solution. Also, do not shake or dilute the reconstituted solution. 
  • Use the solution immediately once the vial is open.
  • Do not use the medicine if you see particles in the liquid or change in its color.
  • Do not discard the medicine through household waste or wastewater.

Ingredients and Benefits of Phesgo

Active Ingredients: Pertuzumab and trastuzumab.

They are monoclonal antibodies that attach to HER2, a protein on the cancer cells that signals the rapid growth of tumor cells. This protein is present in large quantities in many breast cancers.

By attaching to HER2, these ingredients prevent HER2 from producing signals that cause the rapid growth of cancer cells. They also activate your immune cells that kill the cancer cells.

The best part is that pertuzumab and trastuzumab attach to a different part of HER2, and their actions complement each other. Thie combined effect slows down the growth and multiplication of cancer cells.

What are Phesgo Side Effects?

Like all the medications, Phesgo also has side effects. It is possible that you may experience the following side effects;

Very common side effects

  • Rash
  • Decrease in red blood cells
  • Hair loss
  • Inflammation of the digestive system
  • Constipation
  • Inability to sleep well
  • Nose bleed
  • Muscle weakness
  • Loss or change in taste
  • Prickling or tingling sensations in the legs and feet
  • Heartburn
  • Pain and redness at the site of injection
  • Itchy, dry, or acne-like skin
  • Cold and cough
  • Sore throat
  • Fever
  • Body pain
  • Producing more tears

Common side effects:

  • Prickling or tingling in your hands
  • Pain even on light touch
  • Loss of coordination and balance
  • Throbbing, sharp jabbing, or burning pain
  • Reduced sensitivity to temperature changes
  • Inflammation of the nail bed
  • Heart disorders

Uncommon side effects:

  • Breathless or dry cough (symptoms of interstitial lung diseases caused by damage of air sacs in the lungs)
  • Fluid around the lungs resulting in breathlessness

This is not a complete list of side effects. If you experience severe side effects or symptoms that are persistent, please contact your doctor immediately.

Contraindications

Inform your healthcare provider in case of an allergy to Phesgo or any other medication, medications made from Chinese hamster ovary cell protein, or any of the ingredients in Phesgo. Ask your pharmacist or check the medication guide for a list of the ingredients.

Do not take or inform your doctor if you have or had following conditions;

  • Heart failure
  • Heart disease
  • Low levels of white blood cells
  • Diarrhea
  • Lung disorders
  • Uncontrolled high blood pressure
  • Heart attack or rhythm disorders
  • A weak immune system
  • Kidney problems
  • Seizures

Besides, inform your doctor if you are pregnant or breastfeeding, or planning to be pregnant. You should use appropriate birth control tools while you are on treatment with Phesgo and seven months after your last dose. You should not breastfeed during the treatment and for seven months after the final dose. Phesgo may cause fetal damage when administered to pregnant females. 

It may not be safe to breastfeed while on Phesgo. Talk to your physician about the risk associated with the therapy.  

Warnings and Precautions of Phesgo

Your doctor may request you to undergo a blood count before initiation of treatment and may continue to do so during the treatment regime.

Your physician would ask you for a regular left ventricular function assessment. In case of symptomatic congestive heart failure, it would result in discontinuation of the treatment. 

Females should undergo regular check-ups for pregnancy as Phesgo may cause fetal damage. 

It may alter your ability to operate machines and drive. If you have chills, fever, dizziness, or allergic reaction, do not operate machines or drive.

Phesgo Interactions

Inform your health worker about other prescription and non-prescription medications that you are taking. Also, inform about vitamins, herbal and nutritional supplements that you are taking or planning to take. 

The following drugs may interact with Phesgo. Please consult or inform your physician if you are or about to take the following medications:

  • Acrivastine
  • Alefacept
  • Alemtuzumab
  • Astemizole
  • Baricitinib
  • Betamethasone
  • Canakinumab
  • Certolizumab
  • Cetirizine
  • Clemastine
  • Clozapine
  • Denosumab
  • Desloratadine
  • Dexamethasone
  • Dimethyl fumarate
  • Diphenhydramine
  • Estradiol
  • Estramustine
  • Etanercept
  • Hydrocortisone
  • Hydroxyzine
  • Lidocaine
  • Loratadine
  • Methdilazine
  • Methylprednisolone
  • Omacetaxine
  • Ozanimod
  • Tripelennamine
  • Triprolidine
  • Warfarin

This is not a complete list of medications that interact with Phesgo. You should consult your physician if you are to initiate a new treatment regime. 

What Are the Benefits of Phesgo?

Phesgo includes two monoclonal antibodies that attach to HER2, a protein on the cancer cells that signals the quick growth of tumor cells. This protein is present in large quantities in many breast cancers.

By attaching to HER2, these ingredients prevent HER2 from producing signals that cause the rapid growth of cancer cells. They also activate your immune cells that kill the cancer cells.

Pertuzumab and trastuzumab attach to a different part of HER2, and their actions complement each other. Thie combined effect slows down the growth and multiplication of cancer cells.

Is There A Generic Version of Phesgo?

No. For now, there is no generic version of Phesgo available in Canada.

How Is This Medication Different from Others In The Treatment Of Ailment?

Phesgo is one of its kind as it has two monoclonal antibodies that work by blocking the chemicals signaling cancer cells to grow.

Who Makes This Drug and What Is Their Manufacturing Record of Success?

Roche, a research-oriented biopharmaceutical company, makes Phesgo. Their expertise in both pharmaceuticals and diagnostics allowing the company to successfully deliver better-targeted therapies.

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