What is Triumeq?
Triumeq is a prescription medication that contains three ingredients dolutegravir, abacavir, and lamivudine. Triumeq is an antiretroviral drug indicated to treat HIV-infected adults and adolescents above 12 years of age weighing at least 40 kgs (88 pounds).
Let us understand more about the medication, including its uses, side effects, and precautions to be followed.
How to use Triumeq?
What are the approved label uses of Triumeq?
- Triumeq is an FDA-approved medication for treating HIV infection in adults and adolescents above 12 years of age. It can be used alone or in combination with other medications to treat HIV infection. For treatment of HIV, it should be prescribed to individuals who weigh at least 40 kgs (88 pounds)
- Triumeq will not cure HIV; however, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV related illness
- Taking this medication along with practicing safer sex techniques and making lifestyle changes could decrease the risk of HIV transmission to other people
What are some off-label uses of Triumeq?
There is no off-label use of the medicine so far.
It may be prescribed for other uses; ask your doctor or pharmacist for more information.
What are the instructions for Triumeq?
The following instructions should be followed while consuming Triumeq:
- Do not stop taking the medication without consulting with your doctor. Follow the instructions on the prescription label and ask your physician or pharmacist if you have any queries regarding the dosing.
- Triumeq is available as a tablet that is to be taken orally. It can be taken with food or without food.
- It is to be taken once a day. Take the medication at the same time every day.
- Take this medication regularly to get the maximum response to the treatment. Do not stop the treatment even if you feel well.
If you miss your dose, take the dose as soon as you remember. However, if it is almost the time of the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the missed dose.
What are the ingredients in Triumeq?
Triumeq is a tablet that 50 mg of Dolutegravir, 600 mg of abacavir, and 300 mg of lamivudine.
Lamivudine and abacavir belong to the nucleoside analog reverse transcriptase inhibitors (NRTIs) class of drugs. While Dolutegravir belongs to the integrase strand transfer inhibitors (INSTIs) class of drugs. Triumeq mainly acts by reducing the amount of HIV in your blood and increasing the number of immune cells. Triumeq does not cure HIV but may decrease the risk of developing AIDS and HIV-related diseases.
How to store and dispose of Triumeq?
- Triumeq can be stored at room temperature between 15°C to 30°C
- Dispense only in original container
- Keep it away from sunlight
- Keep the container tightly closed
- Keep it away from moisture
- Do not remove the desiccant from the bottle
Keep the medication out of sight and reach of children and pets.
Unused, unneeded, or expired medication should be disposed of in special ways to ensure that children, pets, and other people do not consume them. You should not flush the medication in the toilet. The best way to dispose of medication is through a medication take-back program. Talk to your healthcare professional to learn more about the take-back program.
What are the side effects of Triumeq?
Like all the medications, Triumeq also has side effects. It is possible that you may not experience any side effects or may experience minor side effects. Some of the common side effects include:
- Sleep troubles
Triumeq affects your immunity, thus making you vulnerable to certain side effects. Inform your physician immediately if you experience the following symptoms:
- Fever, cold sores, cough, diarrhea, weight loss, wheezing, night sweats are signs of a new infection.
- Trouble in speaking
- Difficulty in swallowing
- Weakness or prickly feeling
- Postural problems
- Problems with eye movement
- Swelling in neck or throat
- In females, menstrual changes
- In men, impotence
Some of the side effects c. You must call your doctor immediately if you experience any of the below-mentioned symptoms:
- Muscle pain
- Stomach pain (upper right part of the stomach)
- Loss of appetite
- Unusual bruising
- Unusual bleeding
- Flu-like symptoms (fever, chills, cough, or feeling cold)
- Irregular heartbeat
- Excessive tiredness
- Dark or yellow-colored urine
- Yellowing of eyes or skin
- Stomach pain accompanied with nausea and vomiting
- Difficulty in breathing
Triumeq may cause other side effects. Call your physician if you experience any unusual problems while on this medication.
What are the most important contraindications when on Triumeq?
Tell your physician or pharmacist about it if you are allergic to abacavir, dolutegravir, or any of its ingredients. If you have any other allergies, do not forget to share the same with the health care professional. Inform your doctor or pharmacist, if you are allergic to Combivir, Epivir, Tivicay, Trizivir, Ziagen, or Dutrebis.
Do not take or inform your doctor if you have or had following conditions:
- Your doctor may screen you for HLA-B*5701, as people with positive results are at a higher risk of experiencing hypersensitivity reactions to Triumeq
- Heart problems
- High Cholesterol
- Any infection that does not go away or that comes and goes
- Kidney disease
- Liver disease
Inform your doctor if you are pregnant or breastfeeding or if you are thinking of getting pregnant. Before initiating the treatment, your physician will ask you to take the pregnancy test. You should not get pregnant while on treatment with Triumeq. Talk to your doctor about effective birth control methods that will suit you during the treatment. If you become pregnant while on treatment, call your doctor immediately as Triumeq may harm your fetus. Lastly, you should not breastfeed if you are HIV infected or if you are taking Triumeq.
What are the warnings and precautions of Triumeq?
Inform your health worker about other prescription, non-prescription medications, and nutritional supplements that you are taking. Also, inform about vitamins and herbal supplements that you are taking or planning to take.
Inform your doctor if you drink or smoke.
Hepatitis B virus infection can worsen in people who have active HBV and if they stop taking Triumeq. Your physician may ask you to unergo a blood test to determine your liver health from time to time for several months after you stop the treatment.
If you are overweight or a woman or have other medical conditions, watch out for symptoms of lactic acidosis (dangerous build-up of lactic acid in your blood). Ask your doctor or pharmacist if you have any queries on this.
What are the most important interactions of Triumeq?
Triumeq may interact with certain supplements, so inform your healthcare worker about all the supplements you are taking or intend to take.
Triumeq may interact with any of the following medications or inform your doctor if you are taking any of the below-mentioned medication:
- Multivitamins containing aluminum, calcium, or magnesium
- Iron supplements
- Buffered aspirin
- St John’s wort
- Other medications for HIV or AIDS
The list mentioned above is not comprehensive, and other drugs may interact with Triumeq. You should mention all the medications that you are taking and consult your doctor before starting the medication.
Can I take Oral Contraceptive Pills While Taking Triumeq?
Yes, you can use oral contraceptive pills while taking Triumeq. It would be best if you inform your physician before taking any contraceptive pill. Moreover, you can ask your physician which contraceptive method will suit you the best before starting the treatment.
When can I Take Triumeq?
Triumeq can be taken any time of the day. It would help if you consumed it at a fixed time so that remembering it becomes easy. It can be taken with or without food.
Is There A Generic Version to Triumeq?
No. For now, there is no therapeutically equivalent version of Triumeq available in Canada.
Who Makes Triumeq and What Is Their Manufacturing Record of Success?
ViiV Healthcare, a pharmaceutical company, has come up with Triumeq. The company specializes in the development of therapies for HIV infection.