What is Sunosi
Sunosi is the first and only dual-acting norepinephrine and dopamine reuptake inhibitor. It is used to manage increased daytime sleepiness in patients with obstructive sleep apnea and narcolepsy.
Excessive daytime sleepiness in these patients may negatively affect their personal and professional life. Sunosi aims to solve the problems of people living with long-standing and incapacitating sleep disorders.
Let’s understand more about the medication, including its uses, side effects, and precautions to be followed.
How to use Sunosi?
What are Sunosi label use?
- Sunosi or Solriamfetol is an oral prescription medication used to treat narcolepsy (a condition that causes excessive daytime sleepiness).
- It is also used along with other treatments or breathing devices to prevent excessive daytime sleepiness caused by obstructive sleep apnea syndrome (a condition in which a person briefly stops breathing or breathes shallowly many times during sleep and cannot sleep adequately).
What are Sunosi off-label uses?
There is no off-label use of the medicine so far.
It may be prescribed for other uses; ask your doctor or pharmacist for more information.
Directions For Use Of Sunosi
- Sunosi is available as a tablet to be taken orally.
- It is usually prescribed once daily with or without food as soon as you wake up.
- Take the medication at the same time every day.
- Do not change the time of taking the medication without consulting your doctor. Take this medication regularly to get the maximum response of the treatment.
- Do not take Sunosi within 9 hours before you plan to sleep, as it may cause difficulty falling asleep.
- Sunosi is available in two strengths; 75 mg and 150 mg. Your doctor may initially start with a low dose and later increase the dose, not more than once in 3 days. The maximum dose is 150 mg once daily.
- Sunosi is a habit-forming drug. Do not consume or take larger doses or take it longer than prescribed by your physician.
- Sunosi may decrease your sleepiness, but it will not cure your sleep disorder. Continue taking the treatment even if you feel well-rested. Do not increase your dose or use the medication for a longer period than prescribed.
- Do not stop taking the medication without consulting with your doctor. Follow the instructions on the prescription label and ask your physician or pharmacist if you do not understand any instructions. Continue the use of breathing devices or other treatments that your physician has prescribed to you.
- If you miss your dose, skip the dose and continue your regular dosing schedule. Do not take a double dose. If you take Sunosi too late in your waking day, you may find it hard to go to sleep.
What are the ingredients and benefits of Sunosi?
Solriamfetol hydrochloride is the active ingredient in Sunosi.
It belongs to the class of medications called dopamine and norepinephrine reuptake inhibitors. Solriamfetol hydrochloride works by increasing dopamine and norepinephrine, which are natural chemicals that regulate sleep and wakefulness.
How to store and dispose of Sunosi?
- Store Sunosi between 20° to 25°C.
- Keep it away from the reach of children and pets.
- Do not discard the medicine through household waste or wastewater.
What are the side effects of Sunosi?
Like all the medications, Sunosi also has side effects. It is possible that you may experience the following side effects. Inform your physician if these symptoms are severe or if they do not do away:
- Stomach pain
- Loss of appetite
- Difficulty in falling asleep or staying asleep
Some of these effects may be serious. If you experience any of them, please get in touch with your physician immediately:
- Hallucinating (seeing things or hearing voices that do not exist)
- Fast, pounding, or irregular heartbeat
- Shortness of breath
- Chest pain
- Aggressive behavior
- Slow or difficult speech
- Changes in vision
- Swelling of hands, ankles, feet or lower legs
- weakness or numbness of an arm or leg
- blurred vision
- frenzied, abnormally excited mood
This is not a complete list. If you experience severe side effects or symptoms that are persistent, please contact your doctor immediately.
What are Sunosi contraindications?
Inform your healthcare provider in case of an allergy to Sunosi or any other medication or any of the ingredients in Sunosi. Ask your pharmacist or check the medication guide for a list of the ingredients.
Do not take or inform your doctor if you have or had following conditions;
- Kidney problems
- Bipolar disorder
- Blood pressure
- Heart problems
- High Cholesterol
Besides, inform your doctor if you are pregnant or breastfeeding or planning to be pregnant. Call your doctor immediately if you get pregnant while you are on Sunosi.
What are some important warnings and precautions when taking Sunosi?
Inform your health worker about other prescription and non-prescription medications that you are taking. Also, inform about vitamins, herbal and nutritional supplements that you are taking or planning to take.
Inform your physician if you drink or have consumed a large amount of alcohol. Also, inform the doctor if you have ever consumed any drugs or overconsumed any prescription medication.
Do not drive a car or operate machinery until you know how the medication affects you. If you have avoided driving a car and doing dangerous activities because of a sleep disorder, you must avoid these activities unless it is suggested to be safe by your doctor.
What medications can interact with Sunosi?
Sunosi may interact with any of the following medications or inform your doctor if you are taking any of the below-mentioned medication:
- monoamine oxidase (MAO) inhibitors. You must not take Sunosi until at least 14 days have passed since you last consumed MAO inhibitor
- Cold medications
- Cold medications
Monitor your blood pressure regularly during the treatment since the medication may increase blood pressure.
The list is not comprehensive, and other drugs may interact with Sunosi. You should mention all the medicines that you are taking and consult your doctor before starting any medication.
Is There A Generic Version of Sunosi?
No. For now, there is no generic version of Sunosi available in Canada.
How Is Sunosi Different from Others In The Treatment Of Daytime Sleepiness?
Sunosi is the first and only dual-acting norepinephrine and dopamine reuptake inhibitor available to manage daytime sleepiness in conditions such as narcolepsy and obstructive sleep apnea.
Who Makes Sunosi and What Is Their Manufacturing Record of Success?
Jazz Pharmaceuticals, a global biopharmaceutical company, makes Sunosi. Their main aim is to transform the lives of patients and their families. They are incredibly successful in manufacturing medicines for people with critical diseases or conditions where treatment options are limited.