Apo Deferasirox

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Buy Apo Deferasirox Online

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Available Form:  

EFFERV. TAB.

Manufacturer name:  

Apotex

Generic name:  

DEFERASIROX

Strength:  

125MG, 250MG, 500MG

What is Apo Deferasirox?

Deferasirox belongs to the class of medications known as iron chelators. It is used to treat the iron overload that occurs when Anemia is treated with frequent blood transfusions.

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Apo Deferasirox Price and Cost Calculator

DEFERASIROX 250MG

DEFERASIROX 500MG

Quantity

Total no. of TABLET(S)

Insurance coverage

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Estimated copay

$44.36

Drug cost

$186.78

Dispensing fee

$7.00

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FREE

Insurance coverage

$149.42

**Actual price will depend on the insurance coverage in your province

How much does Apo Deferasirox cost?

  • The cost of Apo Deferasirox is $6.23 with us here at PocketPills. The cost of Apo Deferasirox can be lower if your insurance covers it. To calculate the total price of purchasing Apo Deferasirox, you should also consider dispensing and delivery fees.

How much is the dispensing fee for Apo Deferasirox

  • The dispensing cost to order Apo Deferasirox with us is only $7. Pocketpills aims to offer you the most affordable Apo Deferasirox price in Canada.
  • Remember, we offer you FREE Shipping in Canada.

Apo Deferasirox 

Indication

Deferasirox belongs to the class of medications known as iron chelators. It is used to treat the iron overload that occurs when Anemia is treated with frequent blood transfusions. It is used in adults and children 6 years and older. It is also used in children 2 to 5 years old for whom deferoxamine is not providing an adequate response. It works by binding to excess iron in the blood and removing it from the body (mainly through the stools), thereby relieving the iron overload caused by blood transfusions. It can also be used to treat chronic iron overload in people 10 years of age and older who have thalassemia and do not require regular blood transfusions.

Your doctor may have suggested Apo Deferasirox for conditions other than those listed in these drug information articles. As well, some forms of Apo Deferasirox may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Apo Deferasirox, speak to your doctor. Do not stop taking Apo Deferasirox without consulting your doctor.

Do not give Apo Deferasirox to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Apo Deferasirox if their doctor has not prescribed it.

Apo Deferasirox 

Dosage

[ for deferasirox dispersible tablets/tablets for suspension]

The usual recommended starting dose of deferasirox is 10 mg to 30 mg per kilogram of body weight per day, depending on the individual. Your doctor will determine the exact dosage that is appropriate for your circumstances.

Deferasirox should be taken once daily at about the same time each day. It should be taken on an empty stomach and at least 30 minutes before the first meal of the day. The tablets must be mixed with water, apple, or orange juice (100 mL of liquid for doses of less than 1 g, and 200 mL for doses of 1 g or more). Drop the tablet into the liquid and stir until the tablet dissolves completely. Drink all the liquid, then add a little water or juice to what is left in the glass and drink that as well. Do not chew or crush the tablets, or swallow them whole.

Do not use milk or carbonated beverages such as soda pop to dissolve the tablets. Milk slows down dissolution and carbonated beverages will foam up.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Apo Deferasirox exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Apo Deferasirox at room temperature, protect it from light and moisture, and keep it out of the reach of children. Leave the medication in its original package until it is time to take a dose.

[for deferasirox tablets or film-coated tablets]

The usual recommended starting dose of deferasirox film-coated tablets is 7 mg to 21 mg per kilogram of body weight per day, depending on the individual. Your doctor will determine the exact dosage that is appropriate for your circumstances.

Deferasirox should be taken once daily at about the same time each day. Take it on an empty stomach or with a light meal. If you cannot swallow whole tablets, the film-coated tablets may be crushed and administered by sprinkling the full dose on a soft food (e.g., yogurt or applesauce). Immediately eat the food that the medication is sprinkled on, and follow the medication with a glass of water. The dose should not be stored for future use.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Apo Deferasirox exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Apo Deferasirox at room temperature, protect it from light and moisture, and keep it out of the reach of children. Leave the medication in its original package until it is time to take a dose.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Apo Deferasirox 

Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Apo Deferasirox. If you are concerned about side effects, discuss the risks and benefits of Apo Deferasirox with your doctor.

The following side effects have been reported by at least 1% of people taking Apo Deferasirox. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • bloating
  • Constipation
  • Diarrhea
  • dizziness
  • Fever
  • hair loss
  • headache
  • heartburn
  • nausea
  • skin colour changes
  • skin rash
  • sore throat
  • stomach pain
  • tiredness
  • trouble sleeping
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • anxiety
  • blurred or cloudy eyesight
  • reduced hearing
  • heartburn or abdominal pain (ulcers) particularly after eating or taking the drug
  • partial vision loss
  • increased frequency of flu-like symptoms or infections
  • signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
  • signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
  • signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • swelling of the arms or legs

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of gastrointestinal (stomach or intestines) bleeding, such as vomiting blood and/or black stools
  • signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)
  • signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
  • symptoms of a Anaphylaxis (severe allergic reaction) (Hives; skin rash; itchy skin; trouble breathing; swelling of the face, lips, tongue, or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Apo Deferasirox.

Apo Deferasirox 

Available form

Dispersible Tablet

125 mg
Each white, round, flat-faced, bevelled-edged tablet debossed with "APO" on one side and "DEF" over "125" on the other side, contains 125 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose.

250 mg
Each white, round, flat-faced, bevelled-edged tablet debossed with "APO" on one side and "DEF" over "250" on the other side, contains 250 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose.

500 mg
Each white, round, flat-faced, bevelled-edged tablet debossed with "APO" on one side and "DEF" over "500" on the other side, contains 500 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose.

Film-Coated Tablet

90 mg
Each white-to-light-blue, modified-capsule-shaped, film-coated tablet engraved "APO" on one side and "DF 90" on the other side, contains 90 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, hydroxypropyl cellulose, hydroxypropyl methylcellulose, indigotine Al Lake 12-14%, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide.

180 mg
Each blue-to-medium-blue, modified-capsule-shaped, film-coated tablet engraved "APO" on one side and "DF 180" on the other side, contains 180 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, hydroxypropyl cellulose, hydroxypropyl methylcellulose, indigotine Al Lake 12-14%, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide.

360 mg
Each blue-to-dark-blue, modified-capsule-shaped film-coated tablet engraved "APO" on one side and "DF 360" on the other side, contains 360 mg of deferasirox. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, hydroxypropyl cellulose, hydroxypropyl methylcellulose, indigotine Al Lake 12-14%, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide.

Apo Deferasirox 

Contraindications

Do not take Apo Deferasirox if you:

  • are allergic to deferasirox or any ingredients of Apo Deferasirox
  • have a low platelet count (less than 50×109/L)
  • have myelodysplastic syndrome (MDS)
  • have rapidly worsening disease and are not likely to be helped with chelation therapy
  • have severe kidney impairment (creatinine clearance less than 60 mL per minute)

Apo Deferasirox 

Precautions

There may be an interaction between deferasirox and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Apo Deferasirox. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Apo Deferasirox 

Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Deferasirox.

Blood counts: Apo Deferasirox can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot).

Your doctor will do blood tests regularly to monitor the number of specific types of blood cells, in your blood.

Dizziness: Deferasirox may cause dizziness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how Apo Deferasirox affects you.

Hearing problems: Deferasirox may cause hearing problems such as decreased hearing or difficulty hearing high-pitched sounds. Your doctor may recommend you have hearing tests before and throughout treatment. If you notice changes in your hearing, contact your doctor as soon as possible.

Heart failure: Apo Deferasirox is not recommended for people with heart failure due to iron overload. If you have heart failure caused by iron overload, discuss with your doctor how Apo Deferasirox may affect your medical condition, how your medical condition or medications may affect the dosing and effectiveness of Apo Deferasirox, and whether any special monitoring is needed.

Kidney function: Deferasirox may cause serious kidney problems, including kidney failure. If you have reduced kidney function or Kidney Disease, discuss with your doctor how Apo Deferasirox may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Deferasirox, and whether any special monitoring is needed.

Your doctor may recommend you have your kidney function tested regularly throughout treatment. This can be done with blood tests.

Liver function: Apo Deferasirox is not recommended for people with severe liver impairment. Deferasirox may cause serious liver problems, including liver failure. If you have reduced liver function or liver disease, discuss with your doctor how Apo Deferasirox may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Deferasirox, and whether any special monitoring is needed.

Your doctor may recommend you have your liver function tested regularly throughout treatment. This can be done with blood tests.

Laboratory tests: Your doctor may recommend regular blood tests to monitor your response to Apo Deferasirox, the effect the medication has on your liver and kidney, and to monitor your blood cell levels.

Lactose intolerance: Apo Deferasirox contains lactose. It is not recommended for people with hereditary galactose intolerance, glucose-galactose malabsorption, or severe lactase deficiency.

If you have poor lactose tolerance, discuss with your doctor how Apo Deferasirox may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Deferasirox, and whether any special monitoring is needed.

Skin rash: Apo Deferasirox may cause a skin rash. Mild-to-moderate rashes often resolve without treatment and do not require any changes in deferasirox therapy. Severe rashes may require a change in dose, or treatment may need to be stopped, as recommended by your doctor. If you notice symptoms including a rash, itching, blistering, or peeling skin, contact your doctor right away.

Stomach problems: Deferasirox can irritate the lining of the stomach and cause indigestion, or in more serious situations, bleeding in the stomach and digestive system. This is more likely to happen when you are also taking other medications that irritate the stomach, such as anti-inflammatory pain relievers (e.g., acetylsalicylic acid or Ibuprofen).

If you have stomach problems, have a history of stomach problems, or are taking any medications that can irritate the stomach, discuss with your doctor how Apo Deferasirox may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Deferasirox, and whether any special monitoring is needed.

Vision problems: Changes to your vision or eyes, such as cloudy vision or Cataracts, may occur with the use of deferasirox. Your doctor may recommend you have eye tests before and throughout treatment. If you notice changes in your vision, contact your doctor as soon as possible.

Pregnancy: Apo Deferasirox should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Apo Deferasirox, contact your doctor immediately.

Breast-feeding: It is not known if deferasirox passes into breast milk. If you are a breast-feeding mother and are taking Apo Deferasirox, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Apo Deferasirox have not been established for children less than 2 years of age. There is limited data on the use of Apo Deferasirox by children aged 2 to 5 years.

Seniors: Seniors are at an increased risk of experiencing side effects related to the kidneys, liver, and heart. If you are a senior, your doctor should closely monitor your condition while you are taking deferasirox.

Apo Deferasirox frequently asked questions

How To Buy Apo Deferasirox Online?

You can buy Apo Deferasirox online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Apo Deferasirox?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Apo Deferasirox in Canada?

Shipping cost for Apo Deferasirox to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Apo Deferasirox delivered to my home?

You could get Apo Deferasirox delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Apo Deferasirox in Canada for free?

You can get Apo Deferasirox for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Apo Deferasirox for free.

Can I consult a doctor online to get Apo Deferasirox?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Apo Deferasirox.

Can I buy Apo Deferasirox without a prescription?

You need a valid prescription to buy Apo Deferasirox from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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