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Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with Rheumatoid Arthritis and osteoarthritis.
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Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with Rheumatoid Arthritis and osteoarthritis. It works by reducing the amount of certain chemicals produced by your body that cause pain and swelling.
Naproxen controlled-release does not cure these conditions nor does it prevent these conditions from getting worse. Apo Naproxen Sr is not recommended for treatment of short-term pain. The full effects of this medication are usually seen within 1 or 2 weeks.
Apo Naproxen Sr may be available under multiple brand names and/or in several different forms. Any specific brand name of Apo Naproxen Sr may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Apo Naproxen Sr may not be used for all of the conditions discussed here.
Your doctor may have suggested Apo Naproxen Sr for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Apo Naproxen Sr, speak to your doctor. Do not stop taking Apo Naproxen Sr without consulting your doctor.
Do not give Apo Naproxen Sr to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Apo Naproxen Sr if their doctor has not prescribed it.
The recommended starting dose of naproxen controlled-release is 750 mg taken once daily.
Your doctor may adjust your dose according to your response. The lowest dose needed to control pain and inflammation should be used.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Naproxen controlled-release is best taken after a meal, or with food or milk. Do not lie down for about 15 minutes to 30 minutes after taking Apo Naproxen Sr. Swallow the tablets whole, and do not crush or chew them.
It is important to take Apo Naproxen Sr exactly as prescribed by your doctor. If you miss a dose take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Apo Naproxen Sr at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Apo Naproxen Sr. If you are concerned about side effects, discuss the risks and benefits of Apo Naproxen Sr with your doctor.
The following side effects have been reported by at least 1% of people taking Apo Naproxen Sr. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Apo Naproxen Sr.
Apo Naproxen Sr is available as a 750 mg controlled-release tablet.
Do not take Apo Naproxen Sr if you:
There may be an interaction between naproxen controlled-release and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Apo Naproxen Sr. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Naproxen Sr.
Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Allergy: Some people who are allergic to other NSAIDs or ASA also experience allergic reactions to naproxen controlled-release. Before you take naproxen controlled-release, inform your doctor about any previous adverse reactions you have had to medications, especially NSAIDs. People who have experienced difficulty breathing after taking ASA or other NSAIDs should not take naproxen controlled-release.
Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Anemia: Apo Naproxen Sr may cause anemia (low red blood cells). If you take Apo Naproxen Sr for a long period of time, your doctor will periodically monitor your red blood cell levels. If you experience symptoms of anemia (e.g., shortness of breath, fatigue, pallor, fast heartbeat), contact your doctor as soon as possible.
Asthma: People with asthma are at increased risk of severe and even fatal allergic reactions (Anaphylaxis (severe allergic reaction)) when taking Apo Naproxen Sr. People with asthma or other breathing problems should discuss with their doctor how Apo Naproxen Sr may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Naproxen Sr, and whether any special monitoring is needed.
Bleeding disorders: Naproxen controlled-release may increase bruising and bleeding from cuts may take longer to stop. People with bleeding disorders, a history of bleeding problems, or those who are taking medications to prevent clotting, should discuss with their doctor how Apo Naproxen Sr may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Naproxen Sr, and whether any special monitoring is needed.
Blood pressure: Naproxen controlled-release may cause an increase in blood pressure, even when there have been no blood pressure problems in the past. People with high blood pressure should discuss with their doctor how Apo Naproxen Sr may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Apo Naproxen Sr and whether any special monitoring is needed. Report any ongoing increase in blood pressure to your doctor as soon as possible.
Drowsiness/reduced alertness: Apo Naproxen Sr may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how Apo Naproxen Sr affects you.
Fluid and electrolyte balance: Apo Naproxen Sr can cause fluid retention and edema. People with conditions that might be affected by fluid retention or contribute to fluid retention (e.g., Congestive Heart Failure, high blood pressure, kidney disease, or reduced kidney function) should be closely monitored by their doctor while taking Apo Naproxen Sr.
Apo Naproxen Sr may cause high blood potassium levels. People most at risk are seniors; people with conditions such as Diabetes or kidney failure; and those taking beta-adrenergic blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin-II receptor antagonists, Cyclosporine, or some diuretics (water pills).
Heart problems: Naproxen controlled-release may increase the risk of heart-related problems such as Heart Attack, Stroke, or Blood Clots. The risk may increase with the length of treatment and for people who already have heart disease (e.g., a history of heart attack or Angina, stroke, transient ischemic attacks, or congestive heart failure), or risk factors for heart disease (e.g., high blood pressure, High Cholesterol, diabetes, smoking, impaired kidney function). Talk to your doctor about the risks and benefits of using Apo Naproxen Sr. To minimize heart-related problems, the lowest dose of naproxen controlled-release should be used for the shortest time possible.
Kidney function: Long-term use of naproxen controlled-release may increase the risk of developing reduced kidney function. This risk is increased for people who already have kidney disease, liver disease, or heart failure; for people who are taking certain medications (e.g., beta-adrenergic blockers, angiotensin converting enzyme [ACE] inhibitors, angiotensin-II receptor antagonists, cyclosporine, or some diuretics [water pills]; and for seniors. Your doctor will monitor your kidney function with blood tests during long-term therapy with naproxen controlled-release.
Liver function: Rarely, this medication can cause decreased liver function. If you experience yellowing of the skin or whites of the eyes, nausea, vomiting, or loss of appetite, contact your doctor immediately. If you take Apo Naproxen Sr for a long period of time, your doctor will periodically check your liver function with blood tests.
Stomach problems: Stomach or duodenal ulcers, perforation, and bleeding from the stomach have occurred with Apo Naproxen Sr. These complications can occur at any time. The risk for ulcers and bleeding increases with higher doses and longer treatment periods. The risk also increases for people with a history of ulcers, for people who smoke or drink large amounts of alcohol, or for people taking certain medications (e.g., Warfarin, ASA, Clopidogrel, Prednisone, Citalopram, Fluoxetine, Paroxetine, Sertraline). Stop taking Apo Naproxen Sr and contact your doctor immediately if you experience symptoms of stomach ulcers or bleeding in the stomach (e.g., bloody or black, tarry stools).
Pregnancy: Apo Naproxen Sr should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Apo Naproxen Sr, contact your doctor immediately.
The use of naproxen controlled-release during the last 3 months of pregnancy may result in harm to the baby or longer labour for the mother. Naproxen controlled-release should not be used during this time.
Apo Naproxen Sr may reduce your ability to become pregnant. Taking Apo Naproxen Sr while trying to become pregnant is not recommended.
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking naproxen controlled-release, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Naproxen controlled-release is not recommended for children under the age of 18 years. The safety and effectiveness of using Apo Naproxen Sr have not been established for children.
Seniors: Seniors appear to have a higher risk of side effects, such as bleeding and kidney problems. They should use the lowest effective dosage for the shortest time period possible.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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