Prometrium

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Available Form:  

CAPSULE

Manufacturer name:  

Merck

Generic name:  

PROGESTERONE

Strength:  

100MG

What is Prometrium?

Prometrium (Progesterone) belongs to the class of medications called progestins. It is used in combination with postmenopausal estrogen replacement therapy (ERT) to prevent the estrogen from thickening the lining of the uterus (a condition known as endometrial hyperplasia).

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Prometrium frequently asked questions

How To Buy Prometrium Online?

You can buy Prometrium online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Prometrium?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Prometrium in Canada?

Shipping cost for Prometrium to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Prometrium delivered to my home?

You could get Prometrium delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Prometrium in Canada for free?

You can get Prometrium for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Prometrium for free.

Can I consult a doctor online to get Prometrium?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Prometrium.

Can I buy Prometrium without a prescription?

You need a valid prescription to buy Prometrium from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

Prometrium Uses

Prometrium (Progesterone) belongs to the class of medications called progestins. It is used in combination with postmenopausal estrogen replacement therapy (ERT) to prevent the estrogen from thickening the lining of the uterus (a condition known as endometrial hyperplasia). This significantly reduces the risk of endometrial cancer. Prometrium (Progesterone) is used for women who have a uterus.

Prometrium (Progesterone) may be available under multiple brand names and/or in several different forms. Any specific brand name of Prometrium (Progesterone) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Prometrium (Progesterone) may not be used for all of the conditions discussed here.

Your doctor may have suggested Prometrium (Progesterone) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Prometrium (Progesterone), speak to your doctor. Do not stop taking Prometrium (Progesterone) without consulting your doctor.

Do not give Prometrium (Progesterone) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Prometrium (Progesterone) if their doctor has not prescribed it.

How should I use Prometrium (Progesterone)?

The recommended dose of Prometrium (Progesterone) is 200 mg daily taken at bedtime for the last 14 days of estrogen treatment per cycle. Women who take high doses of estrogen should receive a Prometrium (Progesterone) dose of 300 mg per day. If the dose is 300 mg daily, 200 mg should be taken at bedtime and 100 mg should be taken 2 hours after breakfast for the last 12 to 14 days of estrogen treatment per cycle.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Prometrium (Progesterone) exactly as prescribed by your doctor. If you are using 200 mg daily and miss a dose of Prometrium (Progesterone) at bedtime (i.e., 2 of the 100 mg capsules), take an extra dose of 100 mg (1 capsule) the following morning and continue taking the rest of the capsules as prescribed by your doctor. If you are taking 300 mg daily and miss a dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Prometrium (Progesterone) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Prometrium Dosage

The recommended dose of Prometrium (Progesterone) is 200 mg daily taken at bedtime for the last 14 days of estrogen treatment per cycle. Women who take high doses of estrogen should receive a Prometrium (Progesterone) dose of 300 mg per day. If the dose is 300 mg daily, 200 mg should be taken at bedtime and 100 mg should be taken 2 hours after breakfast for the last 12 to 14 days of estrogen treatment per cycle.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Prometrium (Progesterone) exactly as prescribed by your doctor. If you are using 200 mg daily and miss a dose of Prometrium (Progesterone) at bedtime (i.e., 2 of the 100 mg capsules), take an extra dose of 100 mg (1 capsule) the following morning and continue taking the rest of the capsules as prescribed by your doctor. If you are taking 300 mg daily and miss a dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Prometrium (Progesterone) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Prometrium Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Prometrium (Progesterone). If you are concerned about side effects, discuss the risks and benefits of Prometrium (Progesterone) with your doctor.

The following side effects have been reported by at least 1% of people taking Prometrium (Progesterone). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal pain or cramping
  • Acne
  • breast pain or tenderness
  • brown spots on exposed skin, possibly long-lasting
  • change of sexual desire
  • difficulty concentrating
  • difficulty wearing contact lenses
  • dizziness
  • drowsiness
  • headache
  • hot flashes
  • short term joint or muscle pain
  • loss or gain of body, facial, or scalp hair
  • mood changes
  • nervousness
  • premenstrual syndrome (PMS)
  • swelling of face, ankles, or feet
  • weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • allergic reaction (e.g., Hives, skin rash, itchiness)
  • breast lump
  • changes in vaginal bleeding, such as:
    • heavier vaginal bleeding between regular monthly periods
    • increased amounts of menstrual bleeding occurring at regular monthly periods
    • lighter vaginal bleeding between menstrual periods
    • stopping of menstrual periods
  • confusion
  • fast or pounding heartbeat
  • increased blood pressure
  • worsened menstrual cramps
  • painful urination
  • pain during sexual intercourse
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of liver problems (e.g., nausea, vomiting, Diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • vaginal itching or discharge
  • worsening Headaches or migraines

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of a blood clot in blood vessels, such as sudden vision change or dizziness, chest pain, pain and swelling in one leg muscle
  • signs of a heart attack (e.g., chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating)
  • signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Prometrium (Progesterone).

Prometrium Available form

Each capsule contains 100 mg of micronized Prometrium (Progesterone). Nonmedicinal ingredients: sunflower oil, gelatin, glycerin, soya lecithin, and titanium dioxide.

Prometrium Contraindications

Do not take Prometrium (Progesterone) if you:

  • are allergic to Prometrium (Progesterone), peanuts (the capsules contain peanut oil), soya, or any ingredients of Prometrium (Progesterone)
  • are or may be pregnant
  • have a history of Blood Clots (e.g., pulmonary Embolism, deep vein thrombosis) or blood clotting disorders
  • have a tumour dependent on Prometrium (Progesterone) or estrogen for growth (e.g., breast or endometrial cancer)
  • have active liver disease
  • have classical migraines
  • have endometrial hyperplasia (overgrowth of the lining of the uterus)
  • have had a Stroke, Heart Attack, or heart disease
  • have partial or complete loss of vision due to blood vessel disease of the eye
  • have unexplained abnormal vaginal bleeding

Prometrium Precautions

There may be an interaction between Prometrium (Progesterone) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Prometrium (Progesterone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Prometrium Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Prometrium (Progesterone).

Important information about estrogen:

  • Estrogen should be used at the lowest dose that relieves your menopausal symptoms for the shortest time period possible.
  • You should not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes.

Breast and Ovarian Cancer: Several studies have shown an association between a modest increase in the risk of developing Breast Cancer or ovarian cancer and the use of hormone replacement therapy during Menopause when taken over the long term. Ask your doctor which cancer screening tests you may need and how to perform breast self-examination. Women who have breast nodules, fibrocystic disease, abnormal mammograms, or a strong family history of breast cancer should be closely monitored by their doctor.

Dementia: Women over the age of 65 receiving combined hormone replacement therapy (estrogen and progestin) may be at increased risk of developing dementia (loss of memory and intellectual function). If you are over 65, talk to your doctor about whether you should be tested for dementia.

Depression: Hormones, such as Prometrium (Progesterone), have been known to cause mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Prometrium (Progesterone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Prometrium (Progesterone), and whether any special monitoring is needed.

If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Prometrium (Progesterone) contact your doctor as soon as possible.

Diabetes: As with other hormone replacement medications, Prometrium (Progesterone) may cause an increase in blood sugar levels and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Prometrium (Progesterone).

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Prometrium (Progesterone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Prometrium (Progesterone), and whether any special monitoring is needed.

Follow-up examinations: It is important to have a follow-up examination 3 to 6 months after starting Prometrium (Progesterone) to assess your response to treatment. Examinations should be done at least once a year after the first one.

Heart Disease: Several studies have demonstrated that the use of estrogen and progestins to treat menopausal symptoms is related to an increased risk of heart disease, blood clots, and stroke. If you have risk factors for heart disease or stroke, discuss with your doctor how Prometrium (Progesterone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Prometrium (Progesterone), and whether any special monitoring is needed.

Occupational hazards: Temporary and occasional drowsiness or dizziness may occur for some people 1 to 4 hours after taking Prometrium (Progesterone), particularly if it is taken with food. If this occurs, avoid activities requiring concentration, good coordination, or reflex action such as driving or operating machinery. In most cases, these problems can be prevented by taking the capsules at the recommended times. The 200 mg dosage should be taken at bedtime. The 300 mg dosage should be divided into two doses: 100 mg 2 hours after breakfast and 200 mg at bedtime.

Vaginal bleeding: Prometrium (Progesterone) can cause changes to your normal pattern of vaginal bleeding. If you experience menstrual bleeding that lasts longer or heavier than usual, contact your doctor.

Pregnancy: Do not take Prometrium (Progesterone) during pregnancy. If you become pregnant while taking Prometrium (Progesterone), contact your doctor immediately.

Breast-feeding: Prometrium (Progesterone) passes into breast milk. If you are a breast-feeding mother and are taking Prometrium (Progesterone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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