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Manufacturer name:  

allergan inc

Generic name:  





Lolo is a low-dose hormonal birth control pill containing two hormones, Norethindrone (a progestin) and Ethinyl estradiol (an estrogen), used to inhibit pregnancy. It is available in tablet form and is administered via the oral route.

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Side effects

Directions for Use

Ingredient and Benefits


Warnings and Precautions


Storage and Disposal

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 Lolo contraceptive pill is useful for 

  • Prevention of pregnancy 

  • Regulation of periods 

  • Treatment of painful periods 

  • Treatment of acne 

  • Prevention of menstrual blood loss

  • Prevention of ovarian cysts

The medication can be prescribed for other uses. Consult with your doctor for detailed information.

Side effects


  • Headache

  • Nausea

  • Spotting or bleeding between menstrual cycles

  • Tender breast

These side effects are generally mild and go away with time.


  • Bloating or fluid retention

  • Discoloured darkening of the skin, particularly on the face

  • Acne

  • Less sexual desire

  • High blood sugar

  • High cholesterol levels

  • Depression, especially if you have a history of depression

  • Weight gain

This is not a complete list of side effects, and others may take place. One must always check with their physician about other possible side effects.

Directions for Use

Synthroid is available in many forms -- tablets, capsules, solution, and intravenous Levothyroxine. Here are the directions for its usage:

  • Administer Synthroid on an empty stomach as a single dose, preferably one hour before breakfast.

  • Avoid taking Synthroid along with other medicines, especially those containing iron and calcium. Take it four hours before or after taking the other medicines as they may affect the absorption of Synthroid.

  • Take the doses recommended by your doctor, as the quantities are based on your age, body weight, and condition.

  • Crush the tablet of Synthroid when it needs to be given to infants and children incapable of swallowing an intact tablet. Mix it in a small quantity (one to two teaspoonfuls) of water and give it using a spoon to the child. Never store the crushed tablet or water mixture, and do not give this medication with any soybean-based infant formula as it may lead to a severe interaction.3

  • Avoid taking Synthroid along with antacids. 

In case of missed dose: Take Synthroid the moment it is possible. However, leave out the missed dose if it is nearly the time for the next dose. Avoid taking two doses at one time.

Ingredient and Benefits

Each blister pack (28 tablets) comprises of:

  • 24 Blue, round (active) tablets, consisting of 1 mg Norethindrone acetate and 10 mcg Ethinylestradiol.

  • 2 white, hexagonal (active) tablets consisting of 10 mcg Ethinylestradiol.

  • 2 brown, round (non-hormonal placebo) tablets consisting of 75 mg ferrous fumarate. These placebo tablets do not serve any therapeutic action.1

The ingredients work synergistically to help in -

  • Prevention of pregnancy

  • Regulation of irregular periods 

  • Treatment of acne and painful periods


LoLo should not be used by women with:

  • History of heart attack or mini-stroke

  • Active liver disease 

  • Cholestatic jaundice

  • Uncontrolled hypertension

  • Suspected or known pregnancy

  • Immobilization for an extended period 

  • History of thromboembolic disorders

  • Endometrial carcinoma 

  • A known or suspected case of breast cancer 

  • History of migraine headaches 

  • Steroid-dependent jaundice 

  • History of pancreatitis associated with severe hypertriglyceridemia

  • Severe hypertension (blood pressure values persistently high ≥160/100 mmHg)

  • History of benign or malignant liver tumours

  • More than 35 years of age and smoking habit

  • History of cerebrovascular disorders

  • Diabetes mellitus 

Allergy to any ingredient in the formulation of Lolo or component of the container.

Warnings and Precautions

Here are few things to be taken care of before using this product:

  • If you are pregnant or think you may be pregnant, inform your physician immediately. If you have just conceived or have a history of abortion after the first three months, it is good to discuss the safe means of birth control with your doctor. It is also better to explore when it is safe to begin using birth control that consists of a form of estrogen like Lolo.

  • In case you have any allergies, inform your doctor about your medical history 

  • Limit your time in the sun because this medication may cause darkening of the face or skin. Apply sunscreen and also make sure to wear protective clothing whenever you're going outdoors

  • Lolo may decrease milk production for mothers, so if you're breastfeeding, consult your doctor

  • Lolo may affect your blood sugar levels. If you have diabetes, check your blood sugar regularly and share the results with your doctor. 

While providing medical history to the doctor, here are the most important conditions that one must discuss with their doctor:

  • History of high cholesterol levels 

  • Vaginal bleeding (history of unexplained vaginal bleeding)

  • Medical history of hypertension (high blood pressure) 

  • Obesity 

  • Thyroid problems (thyroid hormone imbalance disorders) 

  • Cancer (history of breast or endometrial cancer)  

  • Heart problems such as heart valve disease 

  • History of heart attack

  • Migraines 

  • Severe headaches 

  • History of blood clotting disorders 

  • History of stroke 

  • Yellowing of eyes or skin during pregnancy

  • Kidney disease or liver disease 

  • Swelling or edema


Certain medicines or herbal products are found to lower down the efficacy of oral contraceptives, including:

  • Griseofulvin

  • Oxcarbazepine

  • Carbamazepine

  • Felbamate

  • Barbiturates

  • Bosentan

  • St. John’s wort

  • Topiramate

  • Phenytoin

  • Rifampin1

The above may not be a comprehensive list, and other drugs may interact with LoLo. Please inform the

Storage and Disposal

  • Keep this drug out of the reach of children.

  • Store at a controlled room temperature (20 - 25° C)

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Lolo frequently asked questions

What is Lolo, and what is it used for?

Lo Loestrin Fe (Lolo) is a low-dose combination hormonal pill containing two hormones, Norethindrone (a progestin) and Ethinyl estradiol (an estrogen), to inhibit pregnancy. When taken as directed, Lolo helps minimize the chances of getting pregnant. What are the common side effects associated with Synthroid?

What are the common side effects associated with Lolo?

  1. Headaches

  2. Nausea/upset stomach/vomiting

  3. Vaginal spotting/irregular bleeding between periods

  4. Bloating

  5. Fluid retention

How does Lolo work?

Lolo prevents pregnancy by doing the following:

  1. Prevents the ovary from releasing an egg

  2. Thickens the vaginal fluid, which prevents sperm from fertilizing the egg

  3. Changes the lining of the uterus, making it more difficult for a fertilized egg to implant within the womb

  4. If a fertilized egg fails to attach to the uterus, it will pass through the body

How effective is Lolo?

Lolo uses a low-dose combination of estrogen and progesterone. When used as directed by doctors, Lolo is 96-99% effective.

Is Lolo safe?

Lolo is a low-dose birth control pill and is considered the safest because low-dose birth control pills are associated with the lowest risk of causing blood clots.

Do I need a prescription to buy LoLo?

A doctor’s prescription is required to get Lolo. Your doctor/medical professional is best suited to review your medical history and determine whether or not Lolo is the pill for you. If you have queries or concerns, please discuss them with your doctor or pharmacist.

How to use Lolo?

Follow the blister pack and take one pill as directed as per packaging. You should take the first blue pill in the pack within the first 24 hours of their period. In continuation, you have to keep taking the remaining pills in the pack until the last 28th day of the cycle. After the pack is completed, you should continue with the blue pill from a new Lolo pill pack. In case if you miss taking a blue pill during the cycle, they can take the pill as soon as they remember, meaning you might have to take two pills in one day.







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