Adlyxine Starter Pack (Lixisenatide) belongs to a group of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. It is used along with other medications to improve blood glucose (sugar) levels for people with Type 2 Diabetes. It works by helping your body make more insulin and control blood glucose levels.

Adlyxine Starter Pack (Lixisenatide) may be available under multiple brand names and/or in several different forms. Any specific brand name of Adlyxine Starter Pack (Lixisenatide) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Adlyxine Starter Pack (Lixisenatide) may not be used for all of the conditions discussed here.

Your doctor may have suggested Adlyxine Starter Pack (Lixisenatide) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given Adlyxine Starter Pack (Lixisenatide), speak to your doctor. Do not stop using Adlyxine Starter Pack (Lixisenatide) without consulting your doctor.

Do not give Adlyxine Starter Pack (Lixisenatide) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Adlyxine Starter Pack (Lixisenatide) if their doctor has not prescribed it.

The recommended adult starting dose of Adlyxine Starter Pack (Lixisenatide) is 10 µg (micrograms) daily injected subcutaneously (under the skin) on your stomach area (abdomen), upper thigh, or upper arm, exactly as instructed by your doctor or diabetes educator. After 14 days, your doctor may increase the dose to 20 µg once daily. Do not change your dose unless your doctor has told you to do so.

Adlyxine Starter Pack (Lixisenatide) should be injected within an hour before a meal. Choose the most convenient meal and inject it before that same meal each day.

If you are also using insulin, each medication should be injected separately.

Adlyxine Starter Pack (Lixisenatide) is available as a prefilled pen for injection. Read the user manual for instructions on how to properly use Adlyxine Starter Pack (Lixisenatide). If you are not sure how to use Adlyxine Starter Pack (Lixisenatide), contact your doctor or pharmacist.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to take Adlyxine Starter Pack (Lixisenatide) exactly as prescribed by your doctor. If you miss a dose, inject your dose less than 1 hour before your next meal. Do not inject a double dose or increase your dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Adlyxine Starter Pack (Lixisenatide) should be clear and colourless. Do not use Adlyxine Starter Pack (Lixisenatide) if you notice particles or anything unusual in the appearance of the solution.

Store Adlyxine Starter Pack (Lixisenatide) in the refrigerator, do not allow it to freeze, and keep it out of the reach of children. After the first use of the pen, Adlyxine Starter Pack (Lixisenatide) can be stored at room temperature or in the refrigerator for up to 14 days. After 14 days, discard the pen, even if there is medication left in it. To protect Adlyxine Starter Pack (Lixisenatide) from light, always keep the pen cap on when you are not using it. Always store Adlyxine Starter Pack (Lixisenatide) without a needle attached to prevent contamination, infection, and leakage.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Adlyxine Starter Pack (Lixisenatide). If you are concerned about side effects, discuss the risks and benefits of Adlyxine Starter Pack (Lixisenatide) with your doctor.

The following side effects have been reported by at least 1% of people taking Adlyxine Starter Pack (Lixisenatide). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• back or muscle pain
• bloating
• Constipation
• cough
• decreased appetite
• Diarrhea
• dizziness
• Dry Mouth
• excessive sweating
• flu-like illness (Fever, tiredness, body aches)
• gas
• hair loss
• headache
• heartburn
• Motion Sickness
• nausea
• nervousness
• pain, swelling, burning, or bruising at the place of injection
• rash
• runny, stuffy nose or sneezing
• tiredness
• tremor
• upset stomach
• vomiting
• weakness

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• blurred vision
• dehydration from prolonged nausea, vomiting, or diarrhea
• dizziness, especially when standing
• slow, fast, or irregular heartbeat
• muscle pain
• signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine)
• signs of low blood glucose (e.g., anxiety, blurred vision, confusion, difficulty concentrating, difficulty speaking, dizziness, drowsiness, fast heartbeat, feeling jittery, headache, hunger, irritability, nausea, nervousness, numbness or tingling of the lips or tongue, sweating, tiredness, trembling, weakness)
• symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain, strong odour)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• severe Hypoglycemia (e.g., disorientation, loss of consciousness, seizures)
• signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)
• symptoms of a serious allergic reaction (e.g., swelling of the face or throat, difficulty breathing, wheezing, or itchy skin rash)
• unconsciousness

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Adlyxine Starter Pack (Lixisenatide).

10 µg dose Pre-Filled Pen
Each mL of clear, colourless solution contains 0.05 mg of Adlyxine Starter Pack (Lixisenatide). Nonmedicinal ingredients: glycerol, hydrochloric acid/sodium hydroxide solution for pH adjustment, metacresol (2.7 mg/mL), methionine, sodium acetate trihydrate, and water for injection.

20 µg dose Pre-Filled Pen
Each mL of clear, colourless solution contains 0.1 mg of Adlyxine Starter Pack (Lixisenatide). Nonmedicinal ingredients: glycerol, hydrochloric acid/sodium hydroxide solution for pH adjustment, metacresol (2.7 mg/mL), methionine, sodium acetate trihydrate, and water for injection.

Do not use Adlyxine Starter Pack (Lixisenatide) if you:

• are allergic to Adlyxine Starter Pack (Lixisenatide) or any ingredients of the medication
• are pregnant
• are breast-feeding
• have Type 1 Diabetes
• have diabetic ketoacidosis (accumulation of ketones in blood and urine)

There may be an interaction between Adlyxine Starter Pack (Lixisenatide) and any of the following:

• Acetaminophen
• acetylsalicylic acid (Asa)
• androgens (e.g., testosterone)
• antibiotics
• Atorvastatin
• atypical antipsychotics (e.g., Clozapine, Olanzapine, Quetiapine, Risperidone)
• Basiliximab
• birth control pills
• Buserelin
• chloroquine
• corticosteroids (e.g., budesonide, Hydrocortisone, Prednisone)
• diabetes medications (e.g., chlorpropamide,  glyburide, insulin, Metformin, Rosiglitazone)
• Disopyramide
• diuretics ("water pills"; e.g., Furosemide, Hydrochlorothiazide, Indapamide)
• Epinephrine
• estrogens (e.g., conjugated estrogen, Estradiol, ethinyl estradiol)
• Everolimus
• Glucagon
• Goserelin
• Hepatitis C antivirals (e.g., elbasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir)
• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
• hydroxychloroquine
• Lanreotide
• mifepristone
• monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Phenelzine, Rasagiline, Selegiline, Tranylcypromine)
• Niacin
• Octreotide
• Pasireotide
• Pegvisomant
• progestins (e.g., Dienogest, Levonorgestrel, medroxyprogesterone, Norethindrone)
• protein kinase inhibitors (e.g., Ceritinib, Dabrafenib, Nilotinib, Sunitinib)
• quinolone antibiotics (e.g., ciprofloxacin, Norfloxacin, Ofloxacin)
• quinine
• selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
• Sirolimus
• Somatropin
• sulfonamide antibiotics ("sulfas"; e.g., sulfisoxazole, sulfamethoxazole)
• Tacrolimus
• Vorinostat
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Adlyxine Starter Pack (Lixisenatide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.