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Diprivan (Propofol) belongs to a class of medications known as hypnotics or anaesthetics. Hypnotics cause sleep and reduced sensitivity to pain by reducing the movement of pain messages through the nerves.
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Diprivan (Propofol) belongs to a class of medications known as hypnotics or anaesthetics. Hypnotics cause sleep and reduced sensitivity to pain by reducing the movement of pain messages through the nerves. They may cause partial or complete unconsciousness.
Diprivan (Propofol) is used to induce and maintain sleep as part of anesthesia during surgery for adults and children 3 years of age and older. It may be used for adults before an uncomfortable procedure, to relax and reduce awareness but not cause deep sleep. This is referred to as conscious sedation. Diprivan (Propofol) is also used to reduce awareness and cause sleep for adults who are being treated in an intensive care unit. This reduces awareness of surroundings and thus reduces the stress on the body, allowing recovery.
Diprivan (Propofol) may be available under multiple brand names and/or in several different forms. Any specific brand name of Diprivan (Propofol) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Diprivan (Propofol) may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are receiving this medication, speak to your doctor. Do not stop taking Diprivan (Propofol) without consulting your doctor.
Do not give Diprivan (Propofol) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
The dose of Diprivan (Propofol) used depends on why the medication is being given. Your doctor will calculate the appropriate dose based on body weight. Diprivan (Propofol) is given intravenously (through a vein) by an anesthetist (a doctor who specializes anesthesia).
Diprivan (Propofol) should only be used by doctors who have experience with anesthesia and using Diprivan (Propofol). You should be continuously monitored and facilities for maintenance of a person's airway, artificial ventilation, and oxygen enrichment and circulatory resuscitation must be immediately available in case needed.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Diprivan (Propofol) be given exactly as recommended by your doctor. If you miss an appointment to receive Diprivan (Propofol), contact your doctor as soon as possible to reschedule your appointment.
Store Diprivan (Propofol) at room temperature, protect it from freezing and keep it out of the reach of children.
Strict aseptic techniques must always be maintained during handling as Diprivan (Propofol) is a single-use injectable product, and contains no antimicrobial preservatives. The vehicle is capable of supporting rapid growth of microorganisms. Failure to follow aseptic handling procedures may result in microbial contamination causing serious infections which could lead to life-threatening illness such as septic shock.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is used in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who receives Diprivan (Propofol). If you are concerned about side effects, discuss the risks and benefits of Diprivan (Propofol) with your doctor.
The following side effects have been reported by at least 1% of people receiving Diprivan (Propofol). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop using the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are using Diprivan (Propofol).
Each mL of white, oil in water emulsion contains 10 mg Diprivan (Propofol) for IV administration. Nonmedicinal ingredients: soybean oil, glycerol, egg phosphatide, disodium edetate, and water for injection with sodium hydroxide to adjust pH.
Do not use Diprivan (Propofol) if you:
There may be an interaction between Diprivan (Propofol) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Diprivan (Propofol). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Diprivan (Propofol).
Drowsiness/reduced alertness: Diprivan (Propofol) will cause reduced alertness and cause a person to be drowsy even after they have awakened. If you have received Diprivan (Propofol) as part of an outpatient procedure, you should not drive or operate machinery until the effects of Diprivan (Propofol) have completely passed.
Heart disease: Diprivan (Propofol) can caused decreased heart rate or blood pressure. If you have heart disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Diprivan (Propofol), and whether any special monitoring is needed.
Impaired fat (lipid) metabolism: If you have impaired lipid metabolism (e.g., high lipid levels associated with Diabetes, pancreatitis), discuss with your doctor how Diprivan (Propofol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Diprivan (Propofol), and whether any special monitoring is needed.
Impaired kidney and liver function: The safety and effectiveness of using this medication if you have impaired kidney and liver function have not been established.
Seizures: If you have seizures or a history of seizures, discuss with your doctor how Diprivan (Propofol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: There is evidence that a baby who is exposed to Diprivan (Propofol) before birth may experience impaired brain development. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you are or may be pregnant and require Diprivan (Propofol), contact your doctor immediately.
Breast-feeding: Diprivan (Propofol) passes into breast milk. If you are a breast-feeding mother and are taking Diprivan (Propofol), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children less than 3 years of age. There is evidence that the use of Diprivan (Propofol) to treat young children may cause decreased or impaired brain development. Diprivan (Propofol) may be used as part of anesthesia for children 3 years of age and older. It should not be used for children under the age of 18 as sedation in intensive care or conscious sedation.
Seniors: Seniors may be much more likely to experience side effects of Diprivan (Propofol) and may require lower doses.
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