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Metoclopramide belongs to the classes of medications called antiemetics and prokinetics. It is used to improve stomach emptying after surgery or other procedures.
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Metoclopramide belongs to the classes of medications called antiemetics and prokinetics. It is used to improve stomach emptying after surgery or other procedures. It can also be used to prevent nausea after operations and is useful in preventing the nausea and vomiting associated with cancer chemotherapy. It works by speeding up the rate at which the stomach empties and by blocking nausea triggers in the brain.
Metoclopramide may be available under multiple brand names and/or in several different forms. Any specific brand name of Metoclopramide may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Metoclopramide may not be used for all of the conditions discussed here.
Your doctor may have suggested Metoclopramide for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Metoclopramide, speak to your doctor. Do not stop taking Metoclopramide without consulting your doctor.
Do not give Metoclopramide to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Metoclopramide if their doctor has not prescribed it.
The recommended adult dose of metoclopramide for symptoms resulting from delayed stomach emptying ranges from 5 mg to 10 mg 3 or 4 times daily before meals. The recommended dose for children (aged 5 to 14 years) is 2.5 mg to 5 mg 3 times daily before meals. The injectable form of metoclopramide is most often used for the prevention of nausea and vomiting caused by chemotherapy. It is usually given by a health care professional in a hospital. The maximum daily dose for both adults and children is 0.5 mg/kg of body weight.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Metoclopramide exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Metoclopramide at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Metoclopramide. If you are concerned about side effects, discuss the risks and benefits of Metoclopramide with your doctor.
The following side effects have been reported by at least 1% of people taking Metoclopramide. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Metoclopramide.
Each mL contains metoclopramide hydrochloride 5 mg. Nonmedicinal ingredients: hydrochloric acid and/or sodium hydroxide to adjust pH to 2.5 to 6.5, sodium chloride, and water for injection. Preservative-free.
Do not take metoclopramide if you:
Metoclopramide should not be given to children less than one year of age.
There may be an interaction between metoclopramide and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Metoclopramide. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Metoclopramide.
Drowsiness/reduced alertness: Metoclopramide may cause drowsiness and increase the drowsiness caused by alcohol and other drugs. Avoid driving and doing other potentially hazardous activities until you have determined the effect Metoclopramide has on you.
Medical conditions: If you have Epilepsy, Parkinson's Disease, or Kidney Disease, discuss with your doctor how Metoclopramide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Metoclopramide, and whether any special monitoring is needed.
Tardive dyskinesia (TD): Metoclopramide may cause tardive dyskinesia (TD) to develop. TD is a potentially irreversible syndrome of involuntary, repetitive movements of the face and tongue muscles. Although TD appears most commonly in seniors, especially women, it is impossible to predict who will develop TD. The risk of developing TD increases with higher doses and long-term treatment. If you experience muscle twitching or abnormal movements of the face or tongue, contact your doctor as soon as possible.
Pregnancy: Metoclopramide should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Metoclopramide, contact your doctor immediately.
Breast-feeding: Metoclopramide passes into breast milk. If you are a breast-feeding mother and are taking metoclopramide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Metoclopramide should not be used in children less than one year of age. It should only be used in children over one year of age when the benefits of treatment outweigh the risks of side effects. Children may be more at risk of experiencing abnormal involuntary movements such as tremors and abnormal twitching movements, even at recommended dosages.
Seniors: Seniors appear to have a higher risk of side effects with long-term treatment of metoclopramide.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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