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August 8, 2022

August 10, 2022

August 2, 2022
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Available Form:
inj.implant
Manufacturer name:
tersera therapeutics
Generic name:
goserelin
Strength:
10.8MG
Zoladex LA (Goserelin) is a medication that mimics the actions of gonadotropin-releasing hormone (GnRH or LHRH), a hormone that affects the release of sex hormones such as testosterone and estrogen. Zoladex LA (Goserelin), in its long-acting form, is used to treat Prostate Cancer and Endometriosis (a painful condition caused by growth of extra tissue inside or outside the uterus).
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Zoladex LA (Goserelin) is a medication that mimics the actions of gonadotropin-releasing hormone (GnRH or LHRH), a hormone that affects the release of sex hormones such as testosterone and estrogen. Zoladex LA (Goserelin), in its long-acting form, is used to treat Prostate Cancer and Endometriosis (a painful condition caused by growth of extra tissue inside or outside the uterus).
Zoladex LA (Goserelin) works by suppressing the production of testosterone and estrogen.
Zoladex LA (Goserelin) may be available under multiple brand names and/or in several different forms. Any specific brand name of Zoladex LA (Goserelin) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Zoladex LA (Goserelin) may not be used for all of the conditions discussed here.
Your doctor may have suggested Zoladex LA (Goserelin) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are receiving Zoladex LA (Goserelin), speak to your doctor. Do not stop receiving Zoladex LA (Goserelin) without consulting your doctor.
The usual dose of long-acting Zoladex LA (Goserelin) is 10.8 mg injected under the skin on the abdomen every 12 to 13 weeks. The injection is usually given by a health care professional.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.
It is important Zoladex LA (Goserelin) be given exactly as recommended by your doctor. If you miss an appointment to receive Zoladex LA (Goserelin), contact your doctor as soon as possible to reschedule your appointment.
Zoladex LA (Goserelin) is stored at room temperature and should be protected from light and moisture.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Zoladex LA (Goserelin). If you are concerned about side effects, discuss the risks and benefits of Zoladex LA (Goserelin) with your doctor.
The following side effects have been reported by at least 1% of people taking Zoladex LA (Goserelin). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Zoladex LA (Goserelin).
Each depot is supplied as a cylindrical rod containing Zoladex LA (Goserelin) acetate equivalent to 10.8 mg of Zoladex LA (Goserelin). This depot is available as a sterile ready-to-use syringe with a 14 gauge needle for a single subcutaneous injection. Nonmedicinal ingredients: lactide-glycolide copolymer.
Do not use Zoladex LA (Goserelin) if you:
There may be an interaction between Zoladex LA (Goserelin) (long-acting) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Anemia: Reduced testosterone levels contribute to low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired, or pale skin, contact your doctor as soon as possible.
Your doctor will do blood tests regularly to monitor the number of specific types of blood cells, including red blood cells, in your blood.
Depression: Changed levels of hormones in the body have been known to cause mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Zoladex LA (Goserelin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zoladex LA (Goserelin), and whether any special monitoring is needed.
If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, or decreased interest in activities, or notice them in a family member who is taking Zoladex LA (Goserelin), contact your doctor as soon as possible.
Diabetes: Zoladex LA (Goserelin) may cause a loss of blood glucose control, and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Zoladex LA (Goserelin).
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Zoladex LA (Goserelin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zoladex LA (Goserelin), and whether any special monitoring is needed.
Fertility: When estrogen production is stopped, women stop ovulating. As a result of stopping the production of sex hormones, menstrual bleeds will also stop. Once Zoladex LA (Goserelin) has been discontinued, normal ovulation and menstrual bleeding should return in approximately 12 weeks. If you are planning to become pregnant, wait until you have had at least one normal menstrual period. On rare occasions, some women may enter Menopause early and menstruation does not return after stopping treatment.
Heart problems: If you have heart disease or another heart problem such as heart failure or an abnormal heart rhythm, discuss with your doctor how Zoladex LA (Goserelin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zoladex LA (Goserelin), and whether any special monitoring is needed.
Men and the heart: There may be an increased risk of heart-related events (e.g., heart attacks, Stroke, heart-related death) in men being treated for prostate cancer with GnRH medications. Before you start treatment, tell your doctor if you have diabetes, heart disease, had a previous heart attack or stroke, or have cardiovascular risk factors (e.g., high blood pressure, smoking, or cholesterol). If you have any of these conditions, discuss with your doctor how Zoladex LA (Goserelin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zoladex LA (Goserelin), and whether any special monitoring is needed.
Osteoporosis: Zoladex LA (Goserelin) can cause bones to lose thickness. Your doctor will monitor you for this while you are using Zoladex LA (Goserelin). If you have osteoporosis or are at risk for it (e.g., have been smoking or drinking excessive amounts of alcohol for a long time, have a family history of osteoporosis, or are taking medications such as Prednisone or anti-seizure medications), discuss with your doctor how Zoladex LA (Goserelin) may affect your medical condition and whether any special monitoring is needed.
Pituitary tumour: Although very rare, pituitary gland tumours may develop, bleed, or collapse with Zoladex LA (Goserelin) treatment. If you experience severe Headaches, vomiting, loss of eyesight, or unconsciousness, get immediate medical attention.
Short-term worsening of medical condition: For some people, their medical condition may temporarily worsen during the first month of treatment with Zoladex LA (Goserelin). If your medical condition appears to worsen, contact your doctor.
Spine problems: When people with cancer that has spread to their spine receive Zoladex LA (Goserelin), spinal cord compression can occur. If you develop severe pain, numbness or weakness of the arms or legs, or difficulty urinating, contact your doctor immediately.
Pregnancy: Zoladex LA (Goserelin) should not be used during pregnancy. A nonhormonal method of birth control (e.g., condom, diaphragm) should be used during treatment. If you become pregnant while using Zoladex LA (Goserelin), stop receiving Zoladex LA (Goserelin) and contact your doctor.
Breast-feeding: It is not known if Zoladex LA (Goserelin) passes into breast milk. Women should not breast-feed while receiving Zoladex LA (Goserelin) treatment due to risk of harm to the breast-feeding infant.
Children: The safety and effectiveness of using the medication have not been established for children.
References
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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