Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Inspiolto Respimat.
Asthma-related death: The safety and effectiveness of using Inspiolto Respimat to treat asthma symptoms have not been determined. Studies have shown an increase in deaths caused by severe asthma symptoms when LABA medications have been used without a corticosteroid. Inspiolto Respimat should not be used by people with asthma.
Bladder or urinary problems: Tiotropium can worsen symptoms of bladder problems. If you have a history of bladder problems, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Diabetes: Olodaterol, like other beta-agonists, may cause an increase in blood sugar levels (may cause a loss of blood glucose control) and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Inspiolto Respimat.
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Dizziness/blurred vision: Olodaterol - tiotropium may cause dizziness or blurred vision, affecting your ability to safely drive or operate machinery. Avoid these and other hazardous tasks until you know how Inspiolto Respimat affects you.
Enlarged prostate: Tiotropium can worsen symptoms of an enlarged prostate, such as difficulty starting urination. If you have an enlarged prostate, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Glaucoma: People with eye conditions (e.g., glaucoma) are more likely to experience worsening of their conditions and symptoms such as eye pain and swelling, blurred vision, or other unusual changes in their vision. Take extra care to ensure that olodaterol - tiotropium does not come into contact with your eyes. If your eyes have been in contact with olodaterol - tiotropium or you have any of these symptoms, contact your doctor immediately.
Heart rhythm: Beta-agonists such as olodaterol can cause changes to the normal rhythm of the heart, including an irregular heartbeat called QT prolongation. QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death.
Both olodaterol and tiotropium can cause a fluttering of the heartbeat (atrial fibrillation) or rapid heartbeat, increased blood pressure, chest pain and decreased oxygen reaching the heart muscle.
If you are at risk for heart rhythm problems (e.g., people with heart failure, Angina, low potassium or magnesium levels), discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Inhalation-induced bronchospasm: Inhaled forms of medications may cause spasms of the airways, which make breathing difficult. If you experience this problem when using olodaterol - tiotropium, stop using Inspiolto Respimat immediately. Speak to your doctor if you experience any problems with breathing while taking this or other inhaled medication.
Kidney function: Kidney Disease or reduced kidney function may cause Inspiolto Respimat to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Liver function: Liver disease or reduced liver function may cause Inspiolto Respimat to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Seizures: If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Thyroid disease: People who have an over-active thyroid gland may be more sensitive to the effects of olodaterol - tiotropium. If you have thyroid disease, discuss with your doctor how Inspiolto Respimat may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Inspiolto Respimat, and whether any special monitoring is needed.
Pregnancy: Inspiolto Respimat should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Inspiolto Respimat, contact your doctor immediately.
Breast-feeding: It is not known if olodaterol - tiotropium passes into breast milk. If you are a breast-feeding mother and are taking Inspiolto Respimat, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Inspiolto Respimat have not been established for children.
