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Available Form:   Capsule
Manufacturer name:   Bayer
Generic name:   larotrectinib
Strength:   25mg

What is Vitrakvi?

Vitrakvi (Larotrectinib) belongs to a group of cancer-fighting medications called protein kinase inhibitors.  It works by recognizing certain types of cancer cells and blocking the action of chemicals that cause them to divide and grow.

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Vitrakvi frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Vitrakvi in Canada?

Shipping cost for Vitrakvi to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Vitrakvi delivered to my home?

You could get Vitrakvi delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Vitrakvi in Canada for free?

You can get Vitrakvi for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Vitrakvi for free.

Vitrakvi How to Take

Vitrakvi (Larotrectinib) belongs to a group of cancer-fighting medications called protein kinase inhibitors. It works by recognizing certain types of cancer cells and blocking the action of chemicals that cause them to divide and grow. This may slow down or stop cancers from growing and dividing.

Vitrakvi (Larotrectinib) may be used for solid (cancerous) tumours that have spread to other parts of the body (metastasized) or for which surgery is not appropriate, or that have a specific genetic change known as Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion, and there are no other satisfactory treatments available.

Vitrakvi (Larotrectinib) has been granted a notice of compliance with conditions (NOC/c) by Health Canada. This means that Health Canada has approved Vitrakvi (Larotrectinib) to be marketed based on promising evidence of effectiveness, but additional results of studies are needed to verify its effectiveness. An NOC/c is used to allow access to products that are used to treat or prevent serious, life-threatening, or severely debilitating illness.

Vitrakvi (Larotrectinib) may be available under multiple brand names and/or in several different forms. Any specific brand name of Vitrakvi (Larotrectinib) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Vitrakvi (Larotrectinib) may not be used for all of the conditions discussed here.

Your doctor may have suggested Vitrakvi (Larotrectinib) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Vitrakvi (Larotrectinib), speak to your doctor. Do not stop taking Vitrakvi (Larotrectinib) without consulting your doctor.

Do not give Vitrakvi (Larotrectinib) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Vitrakvi (Larotrectinib) if their doctor has not prescribed it.

Discreet Packaging

Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.

Vitrakvi Dosage

The usual adult dose of Vitrakvi (Larotrectinib) is 100 mg taken by mouth, twice a day.

Doses for children are based on the child's body size, specifically the body surface area (BSA). The recommended dose for children is 100 mg per square metre of body surface area and will be calculated by your child's doctor. The maximum dose for children is 100 mg taken twice a day.

Vitrakvi (Larotrectinib) may be taken with food or on an empty stomach. Swallow the capsules whole with some fluid. Do not open, crush, chew, or dissolve the capsules to take them.

Use an oral syringe to measure each dose of the liquid, as this gives a more accurate measurement than household teaspoons.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Vitrakvi (Larotrectinib) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

If you vomit after taking a dose, take your next dose at the regularly scheduled time. Do not replace the vomited dose.

Store the capsule form of Vitrakvi (Larotrectinib) at room temperature in its original package, protect it from light and moisture, and keep it out of the reach of children. The oral solution should be stored in the refrigerator. Do not freeze. Discard the bottle 30 days after opening.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Vitrakvi Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Vitrakvi (Larotrectinib). If you are concerned about side effects, discuss the risks and benefits of Vitrakvi (Larotrectinib) with your doctor.

The following side effects have been reported by at least 1% of people taking Vitrakvi (Larotrectinib). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal pain
  • Constipation
  • cough
  • Diarrhea
  • dizziness
  • fatigue
  • Fever
  • headache
  • loss of appetite
  • muscle and joint aches or pain
  • nausea
  • shortness of breath
  • stuffy nose
  • swelling or pain in the arms, legs, hands, or feet
  • vomiting
  • weakness
  • weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • anxiety
  • balance problems
  • blood in the urine
  • change in mental status, ability to concentrate
  • difficulty speaking
  • difficulty walking normally
  • falls
  • high blood pressure
  • memory problems
  • numbness or tingling in hands and feet
  • signs of Anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
  • signs of dehydration (e.g., decreased urine, dry skin, dry and sticky mouth, sleepiness, dizziness, headache, thirst, confusion)
  • signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
  • signs of low potassium levels in the blood (e.g., weakness, fatigue, muscle cramps, irregular heartbeat)
  • signs of low sodium levels in the blood (e.g., achy, stiff, or uncoordinated muscles; confusion; tiredness; weakness)
  • signs of a skin infection (heat, redness, pain or tenderness on an area of skin)
  • symptoms of low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heartbeat, weakness)
  • tremor

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • delirium
  • signs of Stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)
  • symptoms of blood infection (e.g., high fever, shaking, chills, weakness, fast heartbeat, fast breathing)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Vitrakvi (Larotrectinib).

Automatic Refills

We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.

Vitrakvi Available Form

Capsule

25 mg
Each white opaque, hard gelatin capsule (size 2) with blue printing of "BAYER" cross and "25 mg" on the body of capsule, contains 25 mg of Vitrakvi (Larotrectinib). Nonmedicinal ingredients: gelatin printing ink (shellac, FD&C Blue No. 2 Aluminum Lake, titanium dioxide, propylene glycol, ammonia solution, dimethicone), and titanium dioxide.

100 mg
Each white opaque, hard gelatin capsule (size 0) with blue printing of "BAYER" cross and "100 mg" on the body of capsule, contains 100 mg of Vitrakvi (Larotrectinib). Nonmedicinal ingredients: gelatin printing ink (shellac, FD&C Blue No. 2 Aluminum Lake, titanium dioxide, propylene glycol, ammonia solution, dimethicone), and titanium dioxide.

Oral Solution

20 mg/mL
Each mL of clear yellow to orange liquid solution contains 20 mg of Vitrakvi (Larotrectinib). Nonmedicinal ingredients: bitterness masking flavour (propylene glycol, natural flavour), taste modifier flavour (propylene glycol, glycerol, natural flavour), hydroxypropyl betadex, natural bitterness masking type flavour (glycerol, natural flavor ingredients), natural masking type flavour (glycerol, natural flavour ingredients), Ora-SweetÒ (purified water, sucrose, glycerol, sorbitol, citric acid, sodium dihydrogen phosphate, flavouring and preservative agents methylparahydroxybenzoate and potassium sorbate), purified water, and sodium citrate.

Vitrakvi Contraindications

Do not take Vitrakvi (Larotrectinib) if you are allergic to Vitrakvi (Larotrectinib) or any ingredients of the medication.

We're Here for You

Our pharmacists are happy to answer your questions. Get in touch by text, live chat, phone or email. We're standing by 7 days a week.

Vitrakvi Precautions

There may be an interaction between Vitrakvi (Larotrectinib) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Vitrakvi (Larotrectinib). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Vitrakvi Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Vitrakvi (Larotrectinib).

Drowsiness/reduced alertness: Vitrakvi (Larotrectinib) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how you are affected by Vitrakvi (Larotrectinib).

Kidney function: Kidney Disease or reduced kidney function may cause Vitrakvi (Larotrectinib) to build up in the body, causing side effects. If you have kidney problems, discuss with your doctor how Vitrakvi (Larotrectinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Vitrakvi (Larotrectinib), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Vitrakvi (Larotrectinib).

Liver function: Liver disease or reduced liver function may cause Vitrakvi (Larotrectinib) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Vitrakvi (Larotrectinib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Vitrakvi (Larotrectinib), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Vitrakvi (Larotrectinib).

Pregnancy: Vitrakvi (Larotrectinib) should not be used during pregnancy unless the benefits outweigh the risks. Women of childbearing age who are taking Vitrakvi (Larotrectinib) and women whose partners are taking Vitrakvi (Larotrectinib), should use an effective method of birth control, such as condoms, during treatment and for at least 1 month after stopping the medication. If you become pregnant while taking Vitrakvi (Larotrectinib), contact your doctor immediately.

Breast-feeding: It is not known if Vitrakvi (Larotrectinib) passes into breast milk. If you are a breast-feeding mother and are taking Vitrakvi (Larotrectinib), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Vitrakvi (Larotrectinib) have not been established for infants less than one month of age.

Free Delivery

Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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