Twinject (Epinephrine) belongs to a family of medications called sympathomimetics. These medications resemble chemicals that are normally found in our bodies and are released during stressful situations, such as when we are scared, anxious, or angry.
Available form
Injectable
Dosage
Manufacturer
Amedra Pharmaceuticals
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The usual dose of Twinject (Epinephrine) is based on your body weight, your risk of experiencing a serious allergic reaction, and your ability to tolerate the medication. The usual dose for children and adults who weigh 30 kg or more is 0.3 mg. For adults and children who weigh 15 kg to 30 kg, the dose is 0.15 mg. For children who weigh less than 15 mg, other forms of injectable Twinject (Epinephrine) may be prescribed.
The medication is injected into the thigh with use of an autoinjector, which is a device that resembles a pen. To use the autoinjector, remove the caps on each end. Then, place the red tip of the pen against the thigh and press hard, holding it there to let the plunger activate (the needle will be pushed into the thigh muscle to inject a dose of Twinject (Epinephrine)). The needle can go through clothes. Hold the pen against the thigh as you count to 10. After counting to 10, remove the device from your thigh. Seek medical attention immediately.
If the symptoms have not improved within about 10 minutes, administer a second dose. Prepare the second dose by unscrewing the rounded tip, pulling the syringe from the barrel and sliding the yellow collar off the plunger. Inject the dose by placing the needle into the thigh and pushing the plunger. It is important to know how to use the autoinjector. If you are not sure, ask your doctor, nurse, or pharmacist for a demonstration.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Store Twinject (Epinephrine) at room temperature, protect it from light, and keep it out of the reach of children. The pen should be stored in its original tube. Do not use it if the solution is darker than light yellow or has particles in it.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Twinject (Epinephrine). If you are concerned about side effects, discuss the risks and benefits of Twinject (Epinephrine) with your doctor.
The following side effects have been reported by at least 1% of people taking Twinject (Epinephrine). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Let your doctor or emergency medical attendant know immediately if any of the following side effects occur:Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Twinject (Epinephrine).
Twinject is no longer being manufactured for sale in Canada. For brands that may still be available, search under Twinject (Epinephrine). This article is being kept available for reference purposes only. If you are using Twinject (Epinephrine), speak with your doctor or pharmacist for information about your treatment options.
Twinject (Epinephrine) should not be used by anyone who is allergic to Twinject (Epinephrine) or to any of the ingredients of the medication.
There may be an interaction between Twinject (Epinephrine) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Twinject (Epinephrine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Twinject (Epinephrine).
Accidental injection: If Twinject (Epinephrine) is accidentally injected into areas such as the hands or feet, go to the nearest emergency room for treatment. Twinject (Epinephrine) should only be injected into the thigh.
Asthma: People who have asthma may experience difficulty breathing after using Twinject (Epinephrine). If you have asthma, ensure that you inform any emergency professionals that you have asthma and have used Twinject (Epinephrine). Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Twinject (Epinephrine), and whether any special monitoring is needed.
Diabetes: People with diabetes may experience a temporary increase in blood glucose level after using Twinject (Epinephrine). If you have diabetes, discuss with your doctor how Twinject (Epinephrine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Twinject (Epinephrine), and whether any special monitoring is needed. Be sure to tell any emergency professionals that you have diabetes and that you have used Twinject (Epinephrine).
Glaucoma: The symptoms of glaucoma can be made worse when Twinject (Epinephrine) is used. If you have glaucoma, discuss with your doctor how Twinject (Epinephrine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Twinject (Epinephrine), and whether any special monitoring is needed.
Heart disease: Twinject (Epinephrine) has many effects throughout the body. It narrows the blood vessels, which in turn can increase blood pressure, heart rate and possibly cause irregular heartbeat. If you have heart disease, including high blood pressure, abnormal heartbeat or are taking medications that increase the risk of an irregular heartbeat (e.g., Digoxin, Amiodarone, Sotalol, procainamide), or have an overactive Thyroid, these conditions can be made worse for a short period of time, by using Twinject (Epinephrine). Discuss with your doctor how Twinject (Epinephrine) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Twinject (Epinephrine) and whether any special monitoring is needed.
Be sure to tell any emergency professionals if you have any of these conditions and that you have used Twinject (Epinephrine).
Medical attention: Since the signs and symptoms of an allergic reaction may return after using Twinject (Epinephrine), it is important to get immediate medical attention after using it. You should be close to a hospital or emergency medical help for at least 24 hours after the start of your allergic reaction.
Parkinson's Disease (PD): People with PD may experience temporarily worsened symptoms of PD after using Twinject (Epinephrine).
Pregnancy: Twinject (Epinephrine) should only be used during pregnancy if the benefits outweigh the risks.
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