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Breo Ellipta contains two active ingredients: vilanterol and fluticasone. Vilanterol belongs to a group of medications called long acting bronchodilators (LABAs).
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Breo Ellipta contains two active ingredients: vilanterol and fluticasone. Vilanterol belongs to a group of medications called long acting bronchodilators (LABAs). These medications relax the muscles in the walls of the small air passages in the lung, keeping the air passage open and making it easier to breathe. Fluticasone belongs to a group of medications known as corticosteroids. Corticosteroids reduce inflammation in the lungs and help reduce the swelling and irritation in the walls of the small air passages in the lungs. This helps open the airways and improve breathing.
Fluticasone-vilanterol is used to treat COPD (Chronic Obstructive Pulmonary Disease) (COPD), including chronic Bronchitis or emphysema. Fluticasone - vilanterol may also be used to treat Asthma for certain people. It should only be used for people whose asthma is not well controlled using inhaled corticosteroids along with occasional use of bronchodilators.
It is important to remember that fluticasone - vilanterol is intended for long-term relief and is not intended for immediate relief. Inhalers that contain "reliever" medications with fast action (e.g., salbutamol, terbutaline) will still be needed while using Breo Ellipta.
Breo Ellipta may be available under multiple brand names and/or in several different forms. Any specific brand name of Breo Ellipta may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Breo Ellipta may not be used for all of the conditions discussed here.
Your doctor may have suggested Breo Ellipta for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Breo Ellipta, speak to your doctor. Do not stop taking Breo Ellipta without consulting your doctor.
Do not give Breo Ellipta to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Breo Ellipta if their doctor has not prescribed it.
The recommended adult dose of fluticasone - vilanterol to treat COPD is one inhalation of 100 µg/25 µg once daily, at the same time every day.
When treating asthma, the recommended adult dose of fluticasone - vilanterol is one inhalation of 100 µg/25 µg or 200 µg/ 25 µg inhaled once daily, at the same time every day.
After inhaling the dose of medication, rinse your mouth with water and spit it out, to reduce the chances of developing thrush.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Breo Ellipta be taken exactly as prescribed by your doctor.
Read the package insert or speak with your pharmacist for instructions on using the dispenser properly.
To make sure the medication remains effective, it is very important to use it regularly once a day, exactly as prescribed by your doctor, even when you are not experiencing symptoms of COPD or asthma. To prevent side effects, do not use Breo Ellipta more often than prescribed.
If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Breo Ellipta at room temperature, protect it from light and moisture, and keep it out of the reach of children. Discard any remaining medication 6 weeks after removing the inhaler from the foil package.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Breo Ellipta. If you are concerned about side effects, discuss the risks and benefits of Breo Ellipta with your doctor.
The following side effects have been reported by at least 1% of people taking Breo Ellipta. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Breo Ellipta.
100 µg/25 µg
Breo Ellipta is provided in two strips of foil blisters. On one strip, each blister contains a white dry powder mixture of micronized fluticasone furoate equivalent to 100 µg and lactose monohydrate for inhalation. On the other strip, each blister contains a white dry powder mixture of micronized vilanterol trifenatate equivalent to 25 µg of vilanterol, magnesium stearate, and lactose monohydrate for inhalation administration.
200 µg/25 µg
Breo Ellipta is provided in two strips of foil blisters. On one strip, each blister contains a white dry powder mixture of micronized fluticasone furoate equivalent to 200 µg and lactose monohydrate for inhalation. On the other strip, each blister contains a white dry powder mixture of micronized vilanterol trifenatate equivalent to 25 µg of vilanterol, magnesium stearate, and lactose monohydrate for inhalation administration.
Do not use Breo Ellipta if you:
There may be an interaction between fluticasone - vilanterol and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Breo Ellipta. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Breo Ellipta.
Asthma-related deaths: When used for asthma treatment, another medication in the same class as vilanterol (LABAs) has been linked to an increase in asthma-related deaths. The use of inhaled corticosteroids, such as fluticasone, with LABAs appears to reduce the risk of serious asthma-related events. If you experience worsening symptoms or your "rescue" medications are not as effective as usual, contact your doctor or seek medical attention immediately.
Diabetes: Breo Ellipta may cause an increase in blood sugar levels and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Breo Ellipta.
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Eye problems: Fluticasone may increase the risk of developing cataracts or glaucoma. If you are at risk of developing either of these conditions, have your eyes checked by your doctor before starting long-term treatment with Breo Ellipta. You should have your eyes monitored at regular intervals while using Breo Ellipta.
Heart conditions: Vilanterol may cause increased blood pressure, rapid heart rate or irregular heart rhythms, including an irregular heartbeat called QT prolongation. QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death. If you are at risk for heart rhythm problems (e.g., people with heart failure, Angina, low potassium or magnesium levels), high blood pressure or other heart disease, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Infections: Breo Ellipta, like other corticosteroids, may prevent the early signs of a serious infection from being noticed. Try to limit the amount of time you spend around others who have recently had infections such as Chickenpox or Measles. If you do come into contact with someone who has one of these infections, contact your doctor for advice.
Liver function: Liver disease or reduced liver function may cause fluticasone to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Oral hygiene: Fluticasone may cause thrush infection in the mouth and throat. Adequate oral hygiene is very important in minimizing the overgrowth of microorganisms such as Candidiasis (thrush). To reduce the risk of infection, gargle with water after each use of Breo Ellipta.
Osteoporosis: Long-term use of medications like fluticasone may increase your risk of developing osteoporosis. If you have osteoporosis or are at risk for developing osteoporosis, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Pneumonia: People using fluticasone-vilanterol to treat COPD may be at an increased risk of developing pneumonia. If you experience symptoms of pneumonia, such as fever, chills, shortness of breath, cough or chest pain, get medical attention as soon as possible.
Seizures: People with seizure disorders may be more likely to experience side effects of vilanterol. If you have a seizure disorder, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Steroid medication use: If you have taken or are still taking oral steroid medications over the last several months, consult with your doctor before using Breo Ellipta. In times of stress or during a severe asthma attack, your doctor may want you to start your oral steroid medication again.
Thyroid problems: People with thyroid conditions may be more likely to experience side effects of vilanterol. If you have an overactive thyroid gland, discuss with your doctor how Breo Ellipta may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Breo Ellipta, and whether any special monitoring is needed.
Wheezing: Breo Ellipta may cause the airways to spasm immediately after using the inhaler. If this happens, use your rescue inhaler as soon as possible to relieve the symptoms, then call your doctor as soon as possible.
Pregnancy: Breo Ellipta should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Breo Ellipta, contact your doctor immediately.
Breast-feeding: It is not known if fluticasone - vilanterol passes into breast milk. If you are a breast-feeding mother and are taking Breo Ellipta, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Breo Ellipta is not intended for use by children. The safety and effectiveness of using Breo Ellipta have not been established for children or people under the age of eighteen.
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