Posanol

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Available Form:  

SUSPENSION

Manufacturer name:  

Merck

Strength:  

40MG/ML

What is Posanol?

Posaconazole belongs to the class of medications called antifungals. It is used to prevent certain serious fungal infections for people 13 years of age and older whose immune systems may be weakened by other medications or diseases.

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Posanol frequently asked questions

How To Buy Posanol Online?

You can buy Posanol online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Posanol?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Posanol in Canada?

Shipping cost for Posanol to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Posanol delivered to my home?

You could get Posanol delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Posanol in Canada for free?

You can get Posanol for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Posanol for free.

Can I consult a doctor online to get Posanol?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Posanol.

Can I buy Posanol without a prescription?

You need a valid prescription to buy Posanol from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

Posanol How to Take

Posaconazole belongs to the class of medications called antifungals. It is used to prevent certain serious fungal infections for people 13 years of age and older whose immune systems may be weakened by other medications or diseases. Posaconazole works by killing or stopping the growth of some types of fungi (Candida and Aspergillus) that can cause infections in people.

Posaconazole is also used for people 13 years of age and older to treat Candida infections of the mouth or throat (thrush). It is also used to treat Aspergillus infections that have not improved with other antifungal medications or when these medications have caused side effects.

Posanol may be available under multiple brand names and/or in several different forms. Any specific brand name of Posanol may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Posanol may not be used for all of the conditions discussed here.

Your doctor may have suggested Posanol for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Posanol, speak to your doctor. Do not stop taking Posanol without consulting your doctor.

Do not give Posanol to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Posanol if their doctor has not prescribed it.

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Posanol Dosage

Proper use of posaconazole depends on which formulation of the medication you are taking. Do not switch between taking posaconazole oral suspension and the posaconazole delayed-release tablets without talking to your doctor. The dosing between the suspension and the delayed-release tablets is different.

[Delayed-release tablets]

To prevent serious fungal infections, the recommended dose of posaconazole is 300 mg (3 tablets of 100 mg) twice daily on the first day, then 300 mg (3 tablets of 100 mg) taken once daily thereafter.

For certain fungal infections that have not responded to other medications or when other medications have caused side effects, the recommended dose of posaconazole is 300 mg (3 tablets of 100 mg) twice daily on the first day, then 300 mg (3 tablets of 100 mg) taken once daily thereafter. Posaconazole delayed-release tablets should be swallowed whole. They may be taken with or without food. Do not crush, chew, break or dissolve the tablets as this will destroy the time-release property of Posanol.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor will determine how long the duration of your treatment will be. It is important to use Posanol exactly as prescribed by your doctor. Finish all Posanol, even if you have started to feel better.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Posanol at room temperature, do not allow it to freeze, and keep it out of the reach of children.

[Oral suspension]

To prevent serious fungal infections, the recommended dose of posaconazole oral suspension is 200 mg (5 mL) taken 3 times daily.

For certain fungal infections that have not responded to other medications or when other medications have caused side effects, the recommended dose of posaconazole oral suspension is 400 mg (10 mL) taken twice daily.

For the treatment of thrush, the recommended dose of posaconazole oral suspension is 100 mg (2.5 mL) taken twice daily on the first day, then 100 mg (2.5 mL) taken once daily thereafter.

Posaconazole oral suspension should be given with a meal or nutritional supplement (if food is not tolerated) to help the medication get absorbed into the body. If you are not able to take meals or nutritional supplements your doctor may recommend that you take a dose of 200 mg (5 mL) 4 times daily.

When taking the oral suspension, use the measuring spoon that is provided to measure each dose, as it gives a more accurate measurement than household teaspoons.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor will determine how long the duration of your treatment will be. It is important to use Posanol exactly as prescribed by your doctor. Finish all Posanol, even if you have started to feel better.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Shake the bottle well before each use. The suspension should be used within 4 weeks of opening the bottle. Safely discard any suspension that remains. Store Posanol at room temperature, do not allow it to freeze, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Posanol Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Posanol. If you are concerned about side effects, discuss the risks and benefits of Posanol with your doctor.

The following side effects have been reported by at least 1% of people taking Posanol. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Diarrhea
  • dizziness
  • Dry Mouth
  • fatigue
  • Fever
  • gas
  • headache
  • loss of appetite
  • nausea
  • numbness, prickling, or tingling sensations
  • skin rash
  • sleepiness
  • tremor
  • upset stomach
  • vomiting
  • weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abnormal heart rhythms (e.g., very fast or slow heartbeat)
  • signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don’t stop bleeding)
  • signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • signs of liver problems (e.g., yellowing of the skin or eyes, flu-like symptoms, fatigue, abdominal pain, light coloured stools, nausea, vomiting)

Stop taking the medication and seek immediate medical attention if any of the following occur:

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Posanol.

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Posanol Available Form

Delayed-release tablet:

Each yellow-coated, capsule-shaped, delayed-release tablet, debossed with “100” on one side of the tablet, contains 100 mg of posaconazole. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropylcellulose, hypromellose acetate succinate, magnesium stearate, microcrystalline cellulose, Opadry† II Yellow [consists of the following ingredients: polyvinyl alcohol partially hydrolyzed, Macrogol/PEG 3350 (Polyethylene Glycol 3350), titanium dioxide, talc, and iron oxide yellow], and silicon dioxide.

Oral Suspension:

Each mL of white, cherry-flavoured, immediate-release oral suspension contains 40 mg of posaconazole. Nonmedicinal ingredients: artificial cherry flavour, citric acid monohydrate, glycerin, liquid glucose, polysorbate 80, purified water, simethicone, sodium benzoate, sodium citrate dihydrate, titanium dioxide, and xanthan gum.

Solution for Injection

Each 1 mL of clear colourless-to-yellow liquid contains 18 mg of posaconazole. Nonmedicinal ingredients: Betadex Sulfobutyl Ether Sodium (SBECD), edetate disodium, hydrochloric acid, sodium hydroxide, and water for injection.

Posanol Contraindications

Do not take Posanol if you:

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Posanol Precautions

There may be an interaction between posaconazole and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Posanol. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Posanol Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breastfeeding, and any other significant facts about your health. These factors may affect how you should use Posanol.

Abnormal heart rhythms: Posanol can increase the risk of abnormal heart rhythms. Certain medications (e.g., Sotalol, quinidine, thioridazine, Chlorpromazine, droperidol, pimozide, gatifloxacin, moxifloxacin, Mefloquine, pentamidine, arsenic trioxide, probucol, Tacrolimus) can increase the risk of a type of abnormal heart rhythm called QT prolongation, and should not be used in combination with posaconazole. You are more at risk for this type of abnormal heart rhythm and its complications if you:

  • are female
  • are older than 65 years of age
  • have a family history of sudden cardiac death
  • have a history of heart disease or abnormal heart rhythms
  • have a slow heart rate
  • have congenital prolongation of the QT interval
  • have Diabetes
  • have had a Stroke
  • have low potassium, magnesium, or calcium levels
  • have nutritional deficiencies

If you have heart disease and abnormal heart rhythms, or people are taking certain medications (e.g., Verapamil, atazanavir), discuss with your doctor how Posanol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Posanol, and whether any special monitoring is needed.

Allergy to other antifungals: If you are allergic to antifungals that are related to posaconazole (e.g., ketoconazole, fluconazole, itraconazole, or Voriconazole), your doctor will monitor you closely while you are taking Posanol. If you experience any symptoms of an allergic reaction such as a rash, contact your doctor immediately. If you experience symptoms of a serious allergic reaction (hives; difficulty breathing; swelling of the face, mouth, tongue, or throat), get immediate medical attention.

Blood problems: Rarely, serious blood problems (e.g., hemolytic uremic syndrome, thromobotic thrombocytopenic purpura) can occur while taking Posanol. If you experience vomiting, diarrhea, blood in the stools, weakness, paleness, bruising, confusion, fever, contact your doctor immediately. These rare but serious blood problems are more likely to occur when people are also taking Cyclosporine or tacrolimus to prevent transplant rejection.

Glucose: The oral suspension contains glucose. People with galactose or glucose-galactose malabsorption should check with their doctor before taking Posanol.

Liver problems: Decreased liver function or liver disease can cause Posanol to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Posanol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Posanol, and whether any special monitoring is needed.

Posanol can also cause liver problems. Some people experience increases in liver function tests while taking posaconazole. These increases usually return to normal when posaconazole is stopped, and may return to normal without stopping treatment. Some people may experience symptoms of more severe liver problems (nausea, vomiting, abdominal pain, fatigue, yellowing of the skin or eyes, light coloured stools) while taking Posanol. If you experience any of these symptoms, contact your doctor immediately. Your doctor will monitor your liver function while you are taking posaconazole.

Pregnancy: Posanol should not be used during pregnancy unless the benefits outweigh the risks. Women who may become pregnant should use adequate contraception while taking Posanol. If you become pregnant while taking Posanol, contact your doctor immediately.

Breast-feeding: It is not known if posaconazole passes into breast milk. If you are a breast-feeding mother and are taking Posanol, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Posanol have not been established for children under 13 years of age. The safety and effectiveness of the IV form of posaconazole has not been determined for people under 18 years of age.

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References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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