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Available Form:   Tablet
Manufacturer name:   Apotex
Generic name:   loxapine
Strength:   2.5mg, 5mg, 10mg, 25mg

What is Apo Loxapine?

Loxapine belongs to the class of medications called antipsychotics. It is used to treat the symptoms of Schizophrenia.

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Apo Loxapine frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Apo Loxapine in Canada?

Shipping cost for Apo Loxapine to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Apo Loxapine delivered to my home?

You could get Apo Loxapine delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Apo Loxapine in Canada for free?

You can get Apo Loxapine for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Apo Loxapine for free.

Apo Loxapine How to Take

Loxapine belongs to the class of medications called antipsychotics. It is used to treat the symptoms of Schizophrenia. Apo Loxapine is believed to work by changing the way that certain nerve signals work in the brain.

Apo Loxapine may be available under multiple brand names and/or in several different forms. Any specific brand name of Apo Loxapine may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Apo Loxapine may not be used for all of the conditions discussed here.

Your doctor may have suggested Apo Loxapine for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Apo Loxapine, speak to your doctor. Do not stop taking Apo Loxapine without consulting your doctor.

Do not give Apo Loxapine to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Apo Loxapine if their doctor has not prescribed it.

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Apo Loxapine Dosage

The usual recommended starting dose of loxapine is 10 mg twice daily. Your doctor will increase the dose over time until the best results occur with the least amount of side effects. The first doses of the medication may be given by an injection into the muscle. Once the best dose has been reached, the medication is usually taken in tablet or liquid form by mouth. The maximum daily dose should not be more than 250 mg.

Apo Loxapine may be taken with food or with a full 250 mL (8 ounce) glass of milk or water to prevent stomach irritation. Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Apo Loxapine exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

If you are receiving the intramuscular injection form of Apo Loxapine and miss an appointment to receive loxapine, contact your doctor as soon as possible to reschedule your appointment.

Store Apo Loxapine at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Apo Loxapine Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Apo Loxapine. If you are concerned about side effects, discuss the risks and benefits of Apo Loxapine with your doctor.

The following side effects have been reported by at least 1% of people taking Apo Loxapine. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • changes to menstrual periods
  • changed interest in sexual activity
  • confusion
  • Constipation
  • dizziness, lightheadedness, or fainting
  • drowsiness
  • Dry Mouth
  • dry, itchy skin
  • enlargement of breasts (men and women)
  • headache
  • increased sensitivity of skin to sun
  • nasal congestion
  • nausea
  • increased sweating
  • trouble sleeping
  • unusual secretion of milk
  • weight changes
  • vomiting

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blurred vision
  • difficulty controlling urination
  • difficult urination
  • difficulty speaking or swallowing
  • difficulty moving (e.g., shuffling walk, slowed movements, inability to move eyes, eye rolling, drooling, mask-like face)
  • decreased sweating
  • dizziness or fainting when rising from a sitting or lying position
  • fast or irregular heartbeat
  • increased blinking or spasms of eyelid
  • loss of balance control
  • muscle stiffness
  • restlessness or desire to keep moving
  • severe constipation
  • signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worse when breathing in, coughing, coughing up blood, sweating, or passing out)
  • signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood,  bleeding gums, cuts that don’t stop bleeding)
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of infection (symptoms may include Fever or chills, severe Diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
  • symptoms of severely increased blood pressure (e.g., chest pain, blurred vision, dizziness, excessive tiredness, headache, stronger or faster heartbeat)
  • uncontrolled movements (e.g., chewing movements, twisting movements of the neck, trunk, arms, or legs, puffing up cheeks, rapid or fine, worm-like movements of tongue, lip smacking or puckering)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • convulsions (seizures)
  • painful erection or prolonged erection that lasts more than 4 hours
  • signs of an allergic reaction (shortness of breath or difficulty breathing; Hives; swelling of the eyes, mouth, lips, or throat)
  • signs of neuroleptic malignant syndrome (e.g., confusion, reduced consciousness, high fever, or muscle stiffness)
  • signs of Stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)
  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Apo Loxapine.

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Apo Loxapine Available Form

Apo-Loxapine is no longer being manufactured for sale in Canada. For brands that may still be available, search under loxapine. This article is being kept available for reference purposes only. If you are using Apo Loxapine, speak with your doctor or pharmacist for information about your treatment options.

Apo Loxapine Contraindications

Loxapine should not be taken by anyone who:

  • is allergic to loxapine or to any of the ingredients of the medication
  • is experiencing circulatory collapse
  • is in a coma
  • is in a severe drug-induced depressed state from drugs such as alcohol, barbiturates, or narcotics

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Apo Loxapine Precautions

There may be an interaction between loxapine and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Apo Loxapine. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Apo Loxapine Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Loxapine.

Blood Clots: Apo Loxapine may increase the chance of blood clot formation, causing reduction of blood flow to organs or the extremities.

If you have a history of clotting you may be at increased risk of experiencing blood clot-related problems such as Heart Attack, stroke, or clots in the deep veins of your leg. Discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision, or difficulty speaking, contact your doctor immediately.

Blood counts: Apo Loxapine can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot). Your doctor will do blood tests to monitor this. If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.

Drowsiness/reduced alertness: Loxapine may impair mental or physical abilities, especially during the first few days of treatment. Avoid activities requiring alertness (e.g., operating vehicles or machinery) until you know how Apo Loxapine affects you. Alcohol and other sedating drugs can make you even less alert when used at the same time as Apo Loxapine.

Glaucoma: Loxapine can cause the symptoms of glaucoma to become worse. If you have glaucoma, discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed.

Heart disease: Loxapine can cause increased heart rate and severely Low Blood Pressure. If you have any heart conditions, discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed.

Liver function: Liver disease or reduced liver function may cause Apo Loxapine to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Apo Loxapine.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Neuroleptic malignant syndrome (NMS): Loxapine, like other antipsychotic medications, can cause a potentially fatal syndrome known as neuroleptic malignant syndrome (NMS). If you notice the symptoms of NMS such as high fever, muscle stiffness, confusion or loss of consciousness, sweating, racing or irregular heartbeat, or fainting, get immediate medical attention.

Seizures: Loxapine may increase the risk of seizures. If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed.

Stopping the medication: If Apo Loxapine needs to be stopped, it should be done gradually, under the supervision of your doctor. Suddenly stopping loxapine can cause temporary involuntary movements, which may be of concern to some people.

Sunburn: An exaggerated sunburn reaction may occur for some people taking loxapine. Avoid exposure to excessive sunlight, including sunlamps and tanning beds, and use sunblock with minimum SPF 15. Talk to your doctor if you develop skin redness.

Tardive dyskinesia: A syndrome consisting of potentially irreversible, involuntary movements called tardive dyskinesia may develop in people treated with Apo Loxapine. Although the risk of tardive dyskinesia appears to be highest among seniors, especially senior women, it is impossible to predict at the beginning of treatment who is likely to develop the syndrome. Tell your doctor if you start to experience signs of this syndrome, such as repetitive and involuntary movements of the face, arms, legs, or torso.

Urinary problems: Loxapine can cause urinary problems, such as difficulty urinating, to become worse. If you have urinary problems, discuss with your doctor how Apo Loxapine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Loxapine, and whether any special monitoring is needed.

Pregnancy: Apo Loxapine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Apo Loxapine, contact your doctor immediately.

Breast-feeding: It is not known if loxapine passes into breast milk. If you are a breast-feeding mother and are taking Apo Loxapine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Apo Loxapine have not been established for children and adolescents. Its use is not recommended for people under 18 years of age.

Seniors: The safety of using Apo Loxapine has not been established for adults 65 years of age or older. The increased risk of liver, kidney, and heart conditions increases the risk of side effects with the use of loxapine.

There may be a higher risk of strokes, heart attacks, and deaths associated with the use of loxapine by seniors with Dementia. Seek medical attention immediately if you notice the signs and symptoms of a stroke (e.g., sudden weakness or numbness, speech problems, vision problems, dizziness, confusion, sudden severe headache) or a heart attack (e.g., discomfort or pain in the chest, back, neck, jaw, arms; sweating; shortness of breath; nausea; lightheadedness) or infection (e.g., pneumonia). Loxapine should not be used in seniors with dementia.

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References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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