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Available Form:   Tablet
Manufacturer name:   Gilead Sciences
Strength:   400+100mg

What is Epclusa?

Sofosbuvir - velpatasvir is used alone or with ribavirin to treat chronic (long-term) Hepatitis C virus (HCV) infection. This combination product contains 2 medications: sofosbuvir and velpatasvir.

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Epclusa frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Epclusa in Canada?

Shipping cost for Epclusa to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Epclusa delivered to my home?

You could get Epclusa delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Epclusa in Canada for free?

You can get Epclusa for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Epclusa for free.

Epclusa How to Take

Sofosbuvir - velpatasvir is used alone or with ribavirin to treat chronic (long-term) Hepatitis C virus (HCV) infection.

This combination product contains 2 medications: sofosbuvir and velpatasvir. Both of these medications belong to the class of medications called antivirals. Sofosbuvir and velpatasvir work by blocking different steps in the reproduction of the virus, helping to stop the duplication of the virus and allowing the body to get rid of the virus.

Epclusa may be available under multiple brand names and/or in several different forms. Any specific brand name of Epclusa may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Epclusa may not be used for all of the conditions discussed here.

Your doctor may have suggested Epclusa for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Epclusa, speak to your doctor. Do not stop taking Epclusa without consulting your doctor.

Do not give Epclusa to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Epclusa if their doctor has not prescribed it.

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Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.

Epclusa Dosage

The recommended dose of Epclusa for adults and children aged 12 years and older who weigh 30 kg or more is 1 tablet taken by mouth, once daily. It is generally taken for 12 weeks.

Sofosbuvir - velpatasvir can be taken with food or on an empty stomach.

If you vomit within 3 hours of taking the medication, take another dose of the medication. If it is longer than 3 hours since you have taken the medication, do not take another tablet. Continue with your normal dose schedule.

Finish all Epclusa, even if you have started to feel better.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Epclusa exactly as prescribed by your doctor. If you miss a dose, and it is within 18 hours of the missed dose, take it as soon as possible and continue with your regular schedule. If it is more than 18 hours since the missed dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Epclusa in the original packaging, at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Epclusa Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Epclusa. If you are concerned about side effects, discuss the risks and benefits of Epclusa with your doctor.

The following side effects have been reported by at least 1% of people taking Epclusa. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • headache
  • tiredness
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • muscle aches
  • rash
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of a slow heartbeat (e.g., dizziness, fainting, fatigue, shortness of breath, chest pain)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Epclusa.

Discreet Packaging

Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.

Epclusa Available Form

Each pink, diamond-shaped, film-coated tablet debossed with "GSI" on one side and "7916" on the other contains 400 mg of sofosbuvir and 100 mg of velpatasvir. Nonmedicinal ingredients: copovidone, croscarmellose sodium, magnesium stearate, and microcrystalline cellulose; film coating: iron oxide red, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.

Epclusa Contraindications

Do not take Epclusa if you are allergic to sofosbuvir, velpatasvir, or any ingredients of the medication.

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Our pharmacists are happy to answer your questions. Get in touch by text, live chat, phone or email. We're standing by 7 days a week.

Epclusa Precautions

There may be an interaction between sofosbuvir - velpatasvir and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Epclusa. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Epclusa Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Epclusa.

Hepatitis B co-infection: Talk to your doctor before taking Epclusa if you have or have had hepatitis B. People with hepatitis B infection that is dormant may experience a recurrence of the hepatitis B while they are taking sofosbuvir – velpatasvir or after they stop taking Epclusa. This can result in severe liver damage and possibly life-threatening liver failure. If you experience symptoms of worsening liver function, such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Human immunodeficiency virus (HIV) co-infection: Sofosbuvir - velpatasvir has been found to be a safe and effective treatment for hepatitis C, for people who also have HIV infection. Some of the medications used to treat HIV infection may affect sofosbuvir or velpatasvir and change how these medications work in the body. If you have HIV infection, discuss with your doctor how Epclusa may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Epclusa, and whether any special monitoring is needed.

Liver transplant: The safety and effectiveness of using sofosbuvir - velpatasvir after having a liver transplant have not been determined. Epclusa is not recommended for anyone who has had a liver transplant.

Pregnancy and contraception: The use of Epclusa is not recommended for pregnant women or women who may become pregnant, as it is not known if sofosbuvir - velpatasvir will harm an unborn child. If you become pregnant while taking Epclusa, contact your doctor immediately.

If you are using ribavirin along with sofosbuvir - velpatasvir, you must use 2 forms of effective birth control (one for each partner) during treatment and for 6 months after stopping the medication. During this time, women will have monthly pregnancy tests to ensure they are not pregnant. Tell your doctor immediately if you become pregnant while using Epclusa.

Breast-feeding: It is not known if sofosbuvir or velpatasvir pass into breast milk. If you are breast-feeding and are taking Epclusa, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Epclusa have not been established for children less than 12 years of age or who weigh less than 30kg. Epclusa has not been studied for children with moderate or severe liver impairment.

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All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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