Linessa side effects can be mild or severe, temporary or permanent.

The Linessa side effects listed below are not experienced by everyone who takes Linessa. If you are concerned about side effects, discuss the risks and benefits of Linessa with your doctor.

Common Linessa side effects

The following side effects have been reported by at least 1% of people taking Linessa. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

The most common side effects from Linessa are abdominal cramping or bloating, Acne (usually less common after 3 months of treatment, and may improve if acne already exists), back pain, breast pain, tenderness, or swelling

Some other common side effects from Linessa include:

  • diarrhea
  • dizziness
  • general feeling of being unwell
  • Headaches
  • heartburn
  • nausea
  • painful menstrual cramps
  • unusual tiredness or weakness
  • vomiting
  • weight gain or loss

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Rare Linessa side effects

Check with your doctor as soon as possible if any of the following side effects occur:

  • breast lumps (for women with a history of breast disease)
  • changes in the uterine bleeding pattern during or between menstrual periods, such as:
    • breakthrough bleeding or spotting between periods
    • complete stop of menstrual bleeding for several months in a row, or stop of menstrual bleeding that only occurs sometimes
    • decreased bleeding during periods
    • prolonged bleeding during periods
  • Depression
  • flu-like symptoms (sudden lack of energy, Fever, cough, sore throat)
  • headaches or migraines (for many users, headaches may lessen but for others, they may increase frequency or severity)
  • increased blood pressure
  • signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of  liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • swelling, pain, or tenderness in upper abdominal area
  • symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
  • symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain)
  • unusual swelling of the extremities
  • vaginal infection with vaginal itching or irritation, or thick, white, or curd-like discharge
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Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worse when breathing in, coughing, coughing up blood, sweating, or passing out)
  • signs of a heart attack (e.g., chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating)
  • signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Linessa.

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