Januvia (Sitagliptin) belongs to the group of Diabetes medications called DPP-4 inhibitors. It works by increasing the amount of incretin released by the intestine. Incretin is a hormone that raises insulin levels when blood sugar is high and decreases the amount of sugar made by the body. Januvia (Sitagliptin) is used alone or in combination with other medications to impr...More on Januvia indication

Glyburide is an antidiabetes medication that belongs to the family of medications known as sulfonylureas. It is used to treat high blood sugar (hyperglycemia) in people with Type 2 Diabetes. Antidiabetes medications such as glyburide are used when diet, exercise, and weight reduction have not been found to lower blood sugar well enough on their own. Glyburide increases the release of insulin (a ho...More on Glyburide indication

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Januvia (Sitagliptin). If you are concerned about side effects, discuss the risks and benefits of Januvia (Sitagliptin) with your...More on Januvia side effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Glyburide. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor....More on Glyburide side effects

Januvia (Sitagliptin) should not be taken by anyone who is allergic to Januvia (Sitagliptin) or to any of the ingredients of the medication....More on Januvia contraindications

Do not take glyburide if you: are allergic to glyburide or any ingredients of the medication are allergic to sulfonylurea or sulphonamide medications are breast-feeding or pregnant are in a diabetic coma or pre-coma (a result of hypoglycemia – symptoms include speech and visual disturbances, flushing, trembling, headache, nausea, vomiting) are taking the medication Bosentan are...More on Glyburide contraindications

There may be an interaction between Januvia (Sitagliptin) and any of the following: acetazolamide alcohol alpha-lipoic acids angiotensin converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril) antimalarial medications (e.g., hydroxychloroquine, quinine) antipsychotics (e.g., aripiprazole, clozapine, quetiapine, risperidone) beta-blockers (e.g., acebutolol, carvedilol, metoprol...More on Januvia precautions

There may be an interaction between glyburide and any of the following: Abiraterone acetylsalicylic acid (Asa) Acetazolamide alcohol Amiodarone androgens (e.g., methyltestosterone, nandrolone, testosterone) angiotensin-converting enzyme inhibitors (ACEIs; Captopril, Ramipril) angiotensin receptor blockers (ARBs; e.g., candasartan, Irbesartan, Losartan) Aprepitant atypical...More on Glyburide precautions